CAS: 5159-41-1; 2-Iodobenzyl Alcohol

上下游产品

CAS号88-67-5 邻碘苯甲酸 | CAS号26260-02-6 2-碘苯甲醛 | CAS号100-51-6 苯甲醇 | CAS号609-67-6 2-碘苯甲酰氯 | CAS号62300-07-6 2-(2-iodophenyl... | CAS号18698-96-9 2-碘苯乙酸 | CAS号66370-75-0 2-(2-碘苯基)乙酸甲酯 | CAS号118-92-3 邻氨基苯甲酸 | CAS号106824-45-7 2-己-1-炔基-苯甲醛 | CAS号10602-08-1 2-乙炔苯甲醇 | CAS号110349-15-0 1-iodo-2-pentyl... | CAS号39959-51-8 2-碘苄胺 | CAS号40400-15-5 2-碘苯基乙腈 | CAS号40400-13-3 邻碘溴苄 | CAS号1801-42-9 2.3-二苯基-1-二氢茚酮 | CAS号104-51-8 丁基苯 | CAS号87-41-2 苯酞 | CAS号26059-40-5 2-(2-碘苯基)-1-乙醇

邻碘苯甲酰氯置于sodium Tetrahydroborate体系中,用 1,4-二氧六环 作为反应溶剂,化学反应 1.0H,以98%的收率获得产物2-碘苄醇
参考文献:Acheson,R. Morrin; Lee,Gary C. M.,Journal Of The Chemical Society. Perkin Transactions I,1987,P. 2321-2332
标题:Acheson,R. Morrin; Lee,Gary C. M.,Journal Of The Chemical Society. Perkin Transactions I,1987,P. 2321-2332

专利信息

专利号:US-7102023-B2
优先权日:1999-11-24
标 题:Protecting groups useful in the synthesis of polysaccharides, natural products, and combinatorial libraries
发明人：BUCHWALD STEPHEN L; PLANTE OBADIAH J; SEEBERGER PETER H
权利人:MASSACHUSETTS INST TECHNOLOGY
摘要:One aspect of the present invention relates to optionally substituted halogenated benzyl halides and the like. These compounds are useful as halogenated benzyl ether-based protecting groups for a variety of functional groups. Another aspect of the present invention relates to use of said protecting groups in an orthogonal protecting group strategy for the synthesis of complex molecules that comprise a number of suitable functional groups. Another aspect of the present invention relates to saccharides bearing various arrays of protecting groups of the present invention. Another aspect of the present invention relates to a method of synthesizing an oligosaccharide or glycoconjugate, comprising the steps of: using a saccharide bearing at least one protecting group of the present invention to glycosylate a second molecule to give a product comprising said saccharide; and removing a protecting group of the present invention from said product.

专利号:US-7109377-B2
优先权日:1996-10-16
标 题:Synthesis of combinatorial libraries of compounds reminiscent of natural products
发明人：SCHREIBER STUART L; SHAIR MATTHEW D; TAN DEREK S; FOLEY MICHAEL A; STOCKWELL BRENT R
权利人:HARVARD COLLEGE
摘要:The present invention provides complex compounds reminiscent of natural products and libraries thereof, as well as methods for their production. The inventive compounds and libraries of compounds are reminiscent of natural products in that they contain one or more stereocenters, and a high density and diversity of functionality. In general, the inventive libraries are synthesized from diversifiable scaffold structures, which are synthesized from readily available or easily synthesizable template structures. In certain embodiments, the inventive compounds and libraries are generated from diversifiable scaffolds synthesized from a shikimic acid based epoxyol template. In other embodiments, the inventive compounds and libraries are generated from diversifiable scaffolds synthesized from the pyridine-based template isonicotinamide. The present invention also provides a novel ortho-nitrobenzyl photolinker and a method for its synthesis. Furthermore, the present invention provides methods and kits for determining one or more biological activities of members of the inventive libraries. Additionally, the present invention provides pharmaceutical compositions containing one or more library members.

专利号:US-8859817-B2
优先权日:2011-01-13
标 题:Process for preparation of phenyl carbamate derivatives
发明人：CHOI YONG MOON
权利人:CHOI YONG MOON; BIO PHARM SOLUTIONS CO LTD
摘要:Provided are a process for the preparation of phenyl carbamate derivatives, useful in the treatment of CNS (central nervous system) disorders, an intermediate in the synthesis of the phenyl carbamate derivatives, and a process for preparation of the intermediate.

专利号:WO-2021083438-A1
优先权日:2019-10-30
标 题:Inhibitors of purine nucleoside phosphorylase - synthesis and use thereof for treatment of t-cell acute lymphoblastic leukemia and lymphoma
发明人：SKACEL JAN; JANEBA ZLATKO; MERTLIKOVA KAISEROVA HELENA
权利人:USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR V V I
摘要:The present invention relates to new compounds of general formula I, their synthesis, their pharmaceutically acceptable salts, and their use in treatment of T-cell acute lymphoblastic leukemia and lymphoma.

专利号:US-2003181690-A1
优先权日:1999-11-24
标 题 :Protecting groups useful in the synthesis of polysaccharides, natural products, and combinatorial libraries

专利号:WO-0006525-A9
优先权日:1998-07-25
标题:Synthesis of combinatorial libraries of compounds reminiscent of natural products