CAS: 479-81-2; Au21106

上下游产品

2-苯基-2-哌啶乙酸乙酯 Ethyl 2-Phenyl-2-(Piperidin-1-yl)Acetate 03/06/7550
2-苯基-2-(哌啶-1-基)乙酸甲酯 Methyl 2-Phenyl-2-(Piperidin-1-yl)Acetate 23535-28-6
2-苯基-2-(哌啶-1-基)乙酸 α-Phenyl-α-Piperidino-Essigsaeure 107416-49-9
2-苯基-2-哌啶基-1-乙酰胺 (R,S)-1-(1-Piperidino)Phenylacetamide 7253-67-0

📜2-苯基-2-哌啶乙腈置于盐酸,硫酸体系中,化学反应生成 苯哌乙胺酯
参考文献:Serventi; Marchesi,Bollettino Scientifico Della Facolta Di Chimica Industriale Di Bologna,1957,Vol. 15,P. 114
标题:Serventi; Marchesi,Bollettino Scientifico Della Facolta Di Chimica Industriale Di Bologna,1957,Vol. 15,P. 114

专利信息

专利号:US-4381301-A
优先权日:1980-05-07
标题 :Substituted tricyclic thieno compounds, their synthesis, their use, their compositions and their medicaments
发明人：RAINER GEORG
权利人:BYK GULDEN LOMBERG CHEM FAB
摘要:Substituted thienobenzodiazepinones of the general formula I (I) [wherein R1 denotes a hydrogen atom (-H) or an alkyl radical with 1 to 4 carbon atoms; R2 represents a halogen atom (halo) or has one of the meanings of R1; R3 denotes a halogen atom (halo) or the group -N(R4)R5; R4 denotes an alkyl radical with 1 to 4 carbon atoms or an alkenyl radical with 3 to 5 carbon atoms; R5 has one of the meanings of R4 or represents the group -(CH2)m-N(R6)R7; or R4 and R5, together with the nitrogen atom to which both are bonded, denote a morpholino group, a pyrrolidino group, a piperidino group, a hexahydroazepin-1-yl group, a piperazin-1-yl group (which is optionally substituted in the 4-position by a methyl, ethyl or benzyl group), a 2,4-dimethylpiperazin-1-yl group, or a hexahydro-1H-1,4-diazepin-1-yl group (which is substituted in the 4-position by a methyl or ethyl group); R6 denotes an alkyl group with 1 to 4 carbon atoms; R7 denotes an alkyl group with 1 to 4 carbon atoms; A denotes a straight-chain or branched alkylene group with 1 to 5 carbon atoms; and m denotes 2 or 3] and their acid-addition salts are new compounds. They either have a protective action on the stomach and intestine and are suitable for treating illnesses based on disorders of the stomach or intestine, or they are intermediates for preparing products having protective action. Processes for the preparation of the new pharmacologically-active compounds and of the intermediate products are presented.

专利号:US-7993390-B2
优先权日:2002-02-08
标 题:Implantable or insertable medical device resistant to microbial growth and biofilm formation
发明人：MILLER KATHLEEN M; BUCAY-COUTO WEENNA; LI JIANMIN
权利人:BOSTON SCIENT SCIMED INC
摘要:Disclosed are implantable or insertable medical devices that provide resistance to microbial growth on and in the environment of the device and resistance to microbial adhesion and biofilm formation on the device. In particular, the invention discloses implantable or insertable medical devices that comprise at least one biocompatible matrix polymer region, an antimicrobial agent for providing resistance to microbial growth and/or a microbial adhesion/biofilm synthesis inhibitor for inhibiting the attachment of microbes and the synthesis and accumulation of biofilm on the surface of the medical device. Also disclosed are methods of manufacturing such devices under conditions that substantially prevent preferential partitioning of any of said bioactive agents to a surface of the biocompatible matrix polymer and substantially prevent chemical modification of said bioactive agents.

专利号:US-4363816-A
优先权日:1981-02-02
标 题 :Tricyclic pyrroles, their compositions and their use
发明人：SENN-BILFINGER JOERG
权利人:BYK GULDEN LOMBERG CHEM FAB
摘要:1,4,9,10-tetrahydropyrrolo[3,2-b][1,5]benzodiazepin-10-ones have been found to provide excellent protection for the stomach and intestines of warm-blooded animals. They are useful for the treatment and prophylaxis of such maladies as gastritis, acute and chronic ulcus ventriculi and hyperacid gastric irritation. The compounds are administered enterally or parenterally, usually in a standard dosage form. The disclosure includes key intermediates, methods of synthesis, compositions and use.

专利号:US-4317823-A
优先权日:1979-08-03
标题 :Pyrazolobenzodiazepinones, their intermediates, their compositions and their use
发明人：RAINER GEORG
权利人:BYK GULDEN LOMBERG CHEM FAB
摘要:1-(Lower)alkyl-4-(substituted)aminoalkylcarbonyl-1,4,9,10-tetrahydropy razolo[4,3-b][1,5]benzodiazepin-10-ones are useful, e.g., to protect warm blooded animals against the formation of gastric ulcers. They are active ingredients in otherwise conventional medicament compositions administered enterally or parenterally in standard dosage forms. Their synthesis, their novel intermediates and their acid-addition salts are described.