CAS: 462-47-5; 3-Aminopropanethiol

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CAS号5554-48-3 1,3-噻嗪-2-硫酮 | CAS号77-09-8 酚酞 | CAS号6276-54-6 3-氯丙胺盐酸盐 | CAS号1002-09-1 S-(3-amino-3-ox... | CAS号10017-11-5 烯丙基胺盐酸盐 | CAS号107-11-9 丙烯胺 | CAS号14753-26-5 3-氯丙胺 | CAS号119174-33-3 S-(2-氰乙基)乙硫代酸酯 | CAS号5460-29-7 N-(3-溴丙基)邻苯二甲酰亚胺 | CAS号180-92-7 1-thia-5-azaspi... | CAS号25478-53-9 4H-1,3-Thiazine... | CAS号3592-66-3 2H-1,3-Thiazine... | CAS号3592-68-5 2H-1,3-Thiazine... | CAS号7211-54-3 高半胱胺盐酸盐 | CAS号6638-35-3 2-phenyl-5,6-di... | CAS号92333-46-5 N,N-bis(2-chlor... | CAS号463-22-9 hom°Cystamine | CAS号543-71-5 1,3-thiazinane

📜3-氯丙胺盐酸盐置于sodium Hydroxide,硫化氢体系中,化学反应生成 3-巯基-1-丙胺
参考文献:Addition Of Hydrogen Sulfide To Unsaturated Amines
标题:Addition Of Hydrogen Sulfide To Unsaturated Amines
摘要:
DOI:10.1021/jo01055A030

专利信息

专利号:WO-9517903-A1
优先权日:1993-12-28
标 题:Modular design and synthesis of oxazolone-derived molecules
发明人：HOGAN JOSEPH C JR; CASEBIER DAVID; FURTH PAUL; TU CHENG
权利人:ARQULE PARTNERS L P; HOGAN JOSEPH C JR; CASEBIER DAVID; FURTH PAUL; TU CHENG
摘要:The design and synthesis of novel oxazolone-derived molecular modules and the use of the modules in the construction of new molecules and fabricated materials is disclosed. The new molecules and fabricated materials are molecular recognition agents useful in the design and synthesis of drugs, and have applications in separations and materials science.

专利号:US-5545568-A
优先权日:1992-09-14
标题:Solid phase and combinatorial synthesis of compounds on a solid support
发明人：ELLMAN JONATHAN A
权利人:UNIV CALIFORNIA
摘要:Methods, compositions, and devices for synthesizing combinatorial libraries of various useful compounds, such as benzodiazepines, prostaglandins, β-turn mimetics and glycerol-derived drugs is described. In order to expediently synthesize such combinatorial libraries of derivatives based upon these core structures, a general methodology for the solid phase synthesis of these derivatives is also provided. This disclosure thus also describes an important extension of solid phase synthesis methods to nonpolymeric organic compounds.

专利号:US-9772338-B2
优先权日:2015-10-20
标题 :Materials and methods for the detection of trace amounts of substances in biological and environmental samples
发明人：KABIR ABUZAR; FURTON KENNETH G
权利人:KABIR ABUZAR; FURTON KENNETH G; UNIV FLORIDA INT
摘要:The subject invention provides chemical compositions and synthesis strategies to create molecularly imprinted polymers (MIPs) via sol-gel processes. In a specific embodiment, the subject invention utilizes a(n) organic, inorganic, or metallic template analyte to create a hybrid organic-inorganic or inorganic three-dimensional network possessing cavities complementary to the shape, size, and functional orientation of the template molecule or ions. The subject invention further pertains to the use of the novel MIPs as selective solid phase extraction (SPE) sorbents for pre-concentration and clean-up of trace substances in biological and environmental samples. Synthesis of other molecularly imprinted polymers with environmental, pharmaceutical, chemical, clinical, toxicological, and national security implications can be conducted in accordance with the teachings of the subject invention.

专利号:US-8188113-B2
优先权日:2006-09-14
标 题 :Dihydropyridopyrimidinyl, dihydronaphthyidinyl and related compounds useful as kinase inhibitors for the treatment of proliferative diseases
发明人：FLYNN DANIEL L; PETILLO PETER A; KAUFMAN MICHAEL D; PATT WILLIAM C
权利人:FLYNN DANIEL L; PETILLO PETER A; KAUFMAN MICHAEL D; PATT WILLIAM C; DECIPHERA PHARMACEUTICALS INC
摘要:The present invention relates to novel dihydropyridopyrimidinyl, dihydronaphthyridinyl, and related compounds which are kinase inhibitors and modulator useful for the treatment of various diseases. More particularly, the invention is concerned with such compounds, kinase/compound adducts, methods of treating diseases, and methods of synthesis of the compounds. Preferably, the compounds are useful for the modulation of kinase activity of Raf kinases and disease polymorphs thereof. Compounds of the present invention find utility in the treatment of mammalian cancers and especially human cancers including but not limited to malignant melanoma, colorectal cancer, ovarian cancer, papillary thyroid carcinoma, non small cell lung cancer, and mesothelioma. Compounds of the present invention also find utility in the treatment of rheumatoid arthritis and retinopathies including diabetic retinal neuropathy and macular degeneration.

专利号:US-4532322-A
优先权日:1983-05-23
标题:Preparation of thiazine derivatives
发明人：JACKSON ARTHUR; HEYES GRAHAM
权利人:FINE ORGANICS LTD
摘要:A method for the preparation of a thiazine derivative of the formula ##STR1## where each R is independently selected from hydrogen or a lower alkyl having 1 to 4 carbon atoms, the method comprising reacting together a sulphur donor which is selected from sulfur, ammonium or alkali metal sulfides, ammonium or alkali metal hydrosulfides, or hydrogen sulfide, 1,1-bis(methylthio)-2-nitroethene and a compound of the formula n n H.sub.2 NCR.sub.2 CR.sub.2 CR.sub.2 OSO.sub.3 H n n where each R is as defined above. n A preferred method is for the preparation of tetra-2-(nitromethylene)-2H-1,3-thiazine which possesses broad spectrum insecticidal activity, and is also useful as an intermediate in the synthesis of other insecticides.

专利号:US-4348536-A
优先权日:1975-05-28
标 题 :Odorless catalysts for the synthesis of polyurethanes
发明人：BLAHAK JOHANNES; HUEBNER HANS; KOSTER JOHANNES; MEINERS HANS J; THOMAS HEINZ
权利人:BAYER AG
摘要:The instant invention is directed to novel compounds and the use thereof in producing polyurethane resins. The compounds generally correspond to the following formula: wherein n is an integer of from 1 to 5, R is a C1-C5 alkyl group Y is a C1-C5 alkyl group or a and Z is a where n=0 or 1, X is -O- or and R' is an aliphatic group having from 1 to 15 carbon atoms and may contain ester, ether, or amide groups or tertiary nitrogen and, when m=0, R' may be a hydrogen atom.