CAS: 3163-27-7; 1-(Bromomethyl)Naphthalene

相似化合物

58791-49-4 939-26-4 4542-77-2

上下游产品

CAS号4780-79-4 1-萘甲醇 | CAS号90-12-0 1-甲基萘 | CAS号66-77-3 1-萘甲醛 | CAS号33250-32-7 1-(二甲氧基甲基)萘 | CAS号50-00-0 甲醛 | CAS号91-20-3 萘 | CAS号558-13-4 四溴化碳 | CAS号86-55-5 1-萘甲酸 | CAS号774197-63-6 3-(1-naphthylme... | CAS号13057-17-5 溴甲基甲基醚 | CAS号3243-42-3 3-(1-萘基)丙酸 | CAS号55447-00-2 B°C-3-(1-萘基)-L-丙氨酸 | CAS号151409-77-7 ASISCHEM R38215 | CAS号1466-24-6 1-(dimethoxypho... | CAS号15374-45-5 1,2-二(1-萘基)乙烷 | CAS号4780-79-4 1-萘甲醇 | CAS号66-77-3 1-萘甲醛 | CAS号20109-33-5 Ethanol,2,2'-[(... | CAS号86-55-5 1-萘甲酸 | CAS号5903-23-1 抑芽醚

1-萘甲醇置于1-氯-N,N,2-三甲基丙烯胺,Lithium Bromide体系中,用 氘代乙腈 用作溶剂,化学反应生成1-溴甲基萘
参考文献:一种用卤素取代羟基的温和方法:2.统一的程序和立体化学研究
标题:一种用卤素取代羟基的温和方法:2.统一的程序和立体化学研究
摘要:N,N-二甲基-和n,N-二异丙基-1-卤代-2-甲基-1-丙烯胺是容易获得的用于醇和羟基酸的轻度脱氧卤代的试剂.在这项研究中,我们表明可以通过改变试剂上烷基的大小来调节试剂的反应性:用异丙基取代甲基可以显着提高反应性.然后,我们使用容易获得的α描述了所有脱氧卤化反应的统一程序-氯亚胺作为试剂,带有(溴化,碘化)或不带有(氯化)碱性溴化物或碘化物.最后,我们表明仲醇的脱氧卤化反应具有高度的立体定向性,通常发生构型反转.
Doi:10.1016/j.Tet.2020.131441

专利信息

专利号:US-2025026768-A1
优先权日:2023-06-30
标题:Method for the synthesis of axially chiral organoboron compounds
发明人：PING YIFAN; CHE CHI-MING
权利人:LABORATORY FOR SYNTHETIC CHEMISTRY AND CHEMICAL BIOLOGY LTD
摘要:A highly efficient and atroposelective Rh-catalyzed [2+2+2] cycloaddition for the synthesis of axially chiral aryboron compounds is developed. The reactions of diynes and alkynylborons smoothly occur in an atom-economical manner, affording a variety of C—B atropisomers in excellent yields and enantioselectivities. The protocol features mild conditions, broad substrate scope, and good functional tolerance. The obtained C—B atropisomers show powerful synthetic applications in terms of producing novel chiral phosphine ligands.

专利号:US-5502126-A
优先权日:1993-06-17
标 题 :Process for the synthesis of isoprene butadiene rubber
发明人：BELL ANTHONY J; MATRANA BARRY A; HALASA ADEL F
权利人:GOODYEAR TIRE & RUBBER
摘要:The subject invention relates to a technique for synthesizing rubbery non-tapered, random, copolymers of 1,3-butadiene and isoprene. These rubbery copolymers exhibit an excellent combination of properties for utilization in tire sidewall rubber compounds for truck tires. By utilizing these isoprene-butadiene rubbers in tire sidewalls, tires having improved cut growth resistance can be built without sacrificing rolling resistance. Such rubbers can also be employed in tire tread compounds to improve tread wear characteristics and decrease rolling resistance without sacrificing traction characteristics. This invention more specifically discloses a process for the synthesis of isoprene-butadiene rubbers which comprises copolymerizing isoprene monomer and 1,3-butadiene monomer in an organic solvent in the presence of a catalyst system which is made by the sequential steps of (1) mixing (a) an organoaluminum hydride, (b) a member selected from the group consisting of aliphatic alcohols, cycloaliphatic alcohols, aliphatic thiols, cycloaliphatic thiols, trialkyl silanols, and triaryl silanols, and (c) optionally, 1,3-butadiene in an organic solvent to produce a modified organoaluminum catalyst component; (2) adding an organometallic compound which contains a metal from Group III-B of the Periodic System to the modified organoaluminum catalyst component to produce a Group III-B metal containing catalyst component; and (3) adding a compound which contains at least one labile halogen atom to the Group III-B metal containing catalyst component.

专利号:US-5554788-A
优先权日:1992-10-01
标 题 :Process for the stereoselective synthesis of 3-substituted 2-thiomethylpropionic acids
发明人：HOLLA WOLFGANG; KAMMERMEIER BERNHARD; BECK GERHARD
权利人:HOECHST AG
摘要:PCT No. PCT/EP93/02673 Sec. 371 Date May 15, 1995 Sec. 102(e) Date May 15, 1995 PCT Filed Sep. 30, 1993 PCT Pub. No. WO94/00789 PCT Pub. Date Apr. 14, 1994Process for the stereoselective synthesis of 3-substituted 2-thiomethylpropionic acids Compounds of the formula I I in which R1 and R2 are as defined can be prepared stereoselectively by reaction of acrylic acid or derivatives thereof or propionic acid or derivatives thereof with a chiral auxiliary, reaction with a mercaptan, stereoselective alkylation and subsequent hydrolysis and oxidation.

专利号:US-6495710-B2
优先权日:2000-01-14
标题:Synthesis and use of dimethyl 1,5-naphthalenedicarboxlyates and intermediates therefrom
发明人：MACEK JOHN A; ROSEN BRUCE I; HOLZHAUER JUERGEN K; BRAMLET JOHN S; LILLWITZ LARRY D; SCHNEIDER DAVID J; LANG LAWRENCE L; PASCHKE EDWARD E; WEIS JOHN M; VISWANATH YENAMANDRA; SAKELLARIDES STEFANOS L
权利人:BP CORP NORTH AMERICA INC
摘要:The synthesis of dimethyl-1,5-naphthalenedicarboxylate and polymers and articles formed therefrom is disclosed, as well as applications for dimethyl-1,5-naphthalenedicarboxylate, its corresponding acid 1,5-NDA, and various synthesis intermediates.

专利号:US-12133887-B2
优先权日:2018-12-18
标题 :Chemical synthesis of oligosaccharides of Pseudomonas aeruginosa serotype O11 O-antigen
发明人：YIN JIAN; HU JING; LIU ZHONGHUA; QIN CHUNJUN
权利人:UNIV JIANGNAN
摘要:The disclosure discloses a chemical synthesis method of oligosaccharides of a Pseudomonas aeruginosa serotype O11 O-antigen, and belongs to the field of chemistry. The disclosure includes constructing an O-antigen trisaccharide by using a D-glucose building block, an L-fucosamine building block and a D-fucosamine building block; wherein the D-glucose building block or the L-fucosamine building block is linked with the D-fucosamine building block through a 1,2-α-cis-glycosidic bond, the D-glucose building block is linked with the L-fucosamine building block through a 1,2-β-trans-glycosidic bond, and the construction of the 1,2-α-cis-glycosidic bond is conducted in a mixed solvent; and the mixed solvent includes two or more of dichloromethane, diethyl ether and thiophene. According to the method of the disclosure, D-mannose is taken as a raw material, D-fucose is obtained simply, conveniently and efficiently, depending on suitable mixed solvents, the uniform construction of a cis-glycosidic bond of the D-fucose is achieved, the stereoselectivity can be up to 100%, and a very good application prospect in the aspects of the development of novel medicines and vaccines against Pseudomonas aeruginosa and the like is achieved.

专利号:EP-0492350-B1
优先权日:1990-12-17
标 题 :Process for the production of (S)-vinyl and (S) allenyl gaba
发明人：EVANS JONATHAN C
权利人:MERRELL PHARMA INC
摘要:The present invention is directed to a stereospecific synthesis of (S)-vinyl-GABA, (S)-allenyl-GABA, (S)-5-allenylpyrrolidinone, and (S)-5-vinyl-pyrrolidinone. Another aspect is directed to a class of 1,5-disubstituted-pyrrolidinone intermediates as well as a new class of chiral lactic acid derivatives. t