CAS: 28539-02-8; 1-(Hydroxymethyl)Benzotriazole

该化合物是有机化合物,其特点是苯三甲醇结构,由一个引信化苯和三氮环组成,该化合物一般是白色的,可溶于水和酒精等极地溶剂,具有各种用途,包括作为腐蚀抑制剂,特别是金属防护和聚合物配方中的稳定剂,具有一些特性;氢三甲醇组(CH2OH)的存在增强了其再活性和溶解性,使其能够与金属表面有效互动;此外,1H-苯三甲醇衍生物因其UV吸收能力而闻名,因此对保护材料不受光降解很有价值;该化合物的稳定性和低毒性特征进一步有助于其在工业应用中的用途;

结构式图片

欧盟法规

ECHA物质C&L通报

上下游产品

CAS号95-14-7 苯并三氮唑 | CAS号50-00-0 甲醛 | CAS号1073609-15-0 4-(1H-benzo[1,2... | CAS号100726-41-8 (Benzotriazol-1... | CAS号1352930-09-6 1H-benzo[d][1,2... | CAS号109-99-9 四氢呋喃 | CAS号60-29-7 乙醚 | CAS号111198-02-8 1-(苯氧基甲基)-1H-苯并三唑 | CAS号111184-75-9 N-(1H-苯并三唑-1-基甲... | CAS号2212-45-5 Naphthalene,1,1... | CAS号2388-43-4 Naphthalene,1,1... | CAS号26628-67-1 N-甲基-4,4′-甲撑二苯胺 | CAS号2567-01-3 3-hydroxy-2-met... | CAS号100-15-2 N-甲基-4-硝基苯胺 | CAS号20611-21-6 2-(苯基磺酰基)乙醇

合成工艺路线路线简述

  • 合成目标产物 1H-Benzotriazole-1-Methanol 主要起始原料 1H-Benzotriazole And Formaldehyde
  • (文献来源)合成步骤主要原料 1H-Benzotriazole 和 Formaldehyde
📜(Benzotriazol-1-yl)Methyl Benzoate置于四氢呋喃,Lithium Aluminium Tetrahydride体系中,化学反应生成1H-苯并三唑-1-甲醇
参考文献:Notes-Complex Metal Hydride Reactions. Ii. Reduction Of 1-Hydroxymethyl-And 1-Benzoyloxymethyl-1H-Benzotriazole
标题:Notes-Complex Metal Hydride Reactions. Ii. Reduction Of 1-Hydroxymethyl-And 1-Benzoyloxymethyl-1H-Benzotriazole
摘要:
Doi:10.1021/jo01104A619

海关参考信息

专利信息


专利号:US-2008312430-A1
优先权日:2004-10-20
标题:Method of Preparing or Synthesizing Polyazamacrocycle Derivatives
发明人:CIHELNIK SIMON; DROZ LADISLAV; SRAMEK MARTIN
权利人:THERAPHARM GMBH
摘要:The present invention relates to novel processes for the synthesis of polyazamacrocycle derivatives. Furthermore, the present invention relates to novel polyazamacrocycle derivatives as well as novel intermediates for the synthesis of said polyazamacrocycle derivatives.

专利号:US-10550087-B2
优先权日:2015-11-17
标 题:Process for the preparation of kinase inhibitors and intermediates thereof
发明人:STURDIVANT JILL MARIE; DELONG MITCHELL A; CHAMBOURNIER GILLES; PAMMENT MICHAEL G; FEDIJ VICTOR
权利人:AERIE PHARMACEUTICALS INC
摘要:Described are processes for the synthesis of certain compounds, useful for treating diseases, e.g. eye disease, such as glaucoma and ocular hypertension, in a subject.

专利号:US-9643927-B1
优先权日:2015-11-17
标题:Process for the preparation of kinase inhibitors and intermediates thereof
发明人:STURDIVANT JILL M; DELONG MITCHELL A; CHAMBOURNIER GILLES; PAMMENT MICHAEL G; FEDIJ VICTOR
权利人:AERIE PHARMACEUTICALS INC
摘要:Described are processes for the synthesis of certain compounds, useful for treating diseases, e.g. eye disease, such as glaucoma and ocular hypertension, in a subject.

专利号:CN-107445993-B
优先权日:2017-08-03
标题 :A kind of tire steel cord anti-oxidation tackifier and its synthesis method and application

专利号:CN-107382927-B
优先权日:2017-08-03
标 题:A kind of lubricating agent and its synthesis method and application

专利号:CN-107445993-A
优先权日:2017-08-03
标 题 :A kind of tire steel cord anti-oxidation tackifier and its synthesis method and application

供应商参考报价(招募中)

品牌试剂参考报价(招募中)

📌 第三方产品分析报告

✅ COA系统入驻 | 共享模式

合成参考文献


摘要:Joule, J. A., Science of Synthesis Knowledge Updates, (2010) 2, 377.
摘要:Harris, P. A., Science of Synthesis Knowledge Updates, (2021) 3, 38.
摘要:Kaposi, M.; Witt, J.; Cokoja, M.; Kühn, F. E., Science of Synthesis: C-1 Building Blocks in Organic Synthesis, (2013) 2, 293.
参考文献:10.1107/s1600536810046052
摘要:Zhu XW, Zhang YJ, Zhang CX, Li GS, Qian HY. 1-Chloro-methyl-1H-1,2,3-benzotriazole. Acta Crystallogr Sect E Struct Rep Online. 2010 Nov 13;66(Pt 12):o3173.
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