CAS: 2845-62-7; Benzenesulfonylisocyanate

该化合物是一种活性有机化合物,通常用作化学合成中的磺酰胺剂,其主要优点包括:对核素的高度反应性,能够有效地将苯并硫磺酰胺组引入目标分子;该化合物对于编制全氟辛烷磺酸,磺酰胺和其他含有药物和农用化学用途的衍生物特别有价值;在受控制条件下保持稳定,能够准确处理合成工作流程;异氰酸盐组的电益性有利于对氨,酒精和其他功能组进行选择性反应,使其成为有机化学和药用化学的多用途中间体;在水性条件下适当储存对保持其再活动至关重要.

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合成工艺路线路线简述

    📜Benzolsulfonyl-Oxamoylchlorid置于邻二氯苯体系中,化学反应生成异氰酸苯磺酰酯
    参考文献:The Reactions Of Sulfonamides With Oxalyl Chloride
    标题:The Reactions Of Sulfonamides With Oxalyl Chloride
    摘要:
    Doi:10.1021/jo01032A025

    海关参考信息

    专利信息


    专利号:US-2004028702-A1
    优先权日:2002-07-26
    标 题:Muramic acid derivative compounds
    发明人:MALETIC MILANA M; LEEMAN AARON H; SANTORELLI GINA M; WADDELL SHERMAN T
    摘要:The present invention pertains to the combinatorial synthesis of antibacterial agents that inhibit the Mur-pathway enzymes involved in bacterial cell wall assembly. The method uses p-alkoxybenzylidene as the linker for the attachment of a derivatized muramic acid to the polymeric resin support. This intermediate becomes the starting point for the combinatorial synthesis, which in conjunction with split-pooling techniques allows rapid synthesis of diverse analogues for high-throughput screening (HTS). The invention is further directed to the libraries of these finished compounds that vary at the peptide, N-acyl and anomeric UDP positions.

    专利号:WO-2013105118-A1
    优先权日:2012-01-10
    标题 :A process for synthesis of syn azido epoxide and its use as intermediate the synthesis of amprenavir & saquinavir

    专利号:CN-115515998-A
    优先权日:2020-05-06
    标题 :Synthesis of Polyurethanes by Chain Growth Copolymerization

    专利号:CN-115784938-A
    优先权日:2021-09-10
    标题:One-pot synthesis of urea (meth)acrylate

    专利号:US-5521179-A
    优先权日:1991-04-18
    标题 :Heterocyclic amides
    发明人:BERNSTEIN PETER R; SHAW ANDREW; THOMAS ROYSTON M; WARNER PETER; WOLANIN DONALD J
    权利人:ZENECA LTD
    摘要:The present invention relates to certain novel heterocyclic amides which are 1-pyridylacetamide compounds of formula I, set out herein, which are inhibitors of human leukocyte elastase (HLE), also known as human neutrophil elastase (HNE), making them useful whenever such inhibition is desired, such as for research tools in pharmacological, diagnostic and related studies and in the treatment of diseases in mammals in which HLE is implicated. The invention also includes intermediates useful in the synthesis of these heterocyclic amides, processes for preparing the heterocyclic amides, pharmaceutical compositions containing such heterocyclic amides and methods for their use.

    专利号:WO-2006043121-A1
    优先权日:2004-10-20
    标 题:Oxazolidinone derivatives as antimicrobials
    发明人:MEHTA ANITA; DAS BISWAJIT; RUDRA SONALI; YADAV AJAY SINGH; KUMARI SANGITA; SALMAN MOHAMMAD; RATTAN ASHOK
    权利人:RANBAXY LAB LTD; MEHTA ANITA; DAS BISWAJIT; RUDRA SONALI; YADAV AJAY SINGH; KUMARI SANGITA; SALMAN MOHAMMAD; RATTAN ASHOK
    摘要:The present invention relates to certain substituted phenyl oxazolidinones and to processes for the synthesis of the same. This invention also relates to pharmaceutical compositions containing the compounds of the present invention as antimicrobials. The compounds are useful antimicrobial agents, effective against a number of human and veterinary pathogens, including gram-positive aerobic bacteria such as multiple-resistant staphylococci, streptococci and enterococci as well as anaerobic organisms such as Bacterioides spp. and Clostridia spp. species, and acid fast organisms such as Mycobacterium tuberculosis, Mycobacterium avium and Mycobacterium spp.

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    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    合成参考文献


    摘要:Shaabani, A.; Sarvary, A.; Shaabani, S., Science of Synthesis: Multicomponent Reactions, (2013) 2, 132.
    摘要:Shaabani, A.; Sarvary, A.; Shaabani, S., Science of Synthesis: Multicomponent Reactions, (2013) 2, 164.
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