CAS: 16234-14-3; 2,4-Dichlorothieno[3,2-D]Pyrimidine

上下游产品

CAS号16233-51-5 2,4-二羟基噻吩并[3,2-D]嘧啶 | CAS号22288-78-4 3-氨基-2-噻吩甲酸甲酯 | CAS号57-13-6 尿素 | CAS号885618-31-5 2-氯-4-吗啉代噻吩并[3,... | CAS号957054-30-7 2-(1H-吲唑-4-基)-6... | CAS号1119280-68-0 2-氯噻吩并[3,2-D]嘧啶 | CAS号16234-15-4 2-氯-4-(4-吗啉基)噻吩... | CAS号1245811-20-4 2-氯噻吩并[3,2-d]嘧啶... | CAS号1152475-42-7 7-溴-2-氯噻吩并[3,2-d]嘧啶 | CAS号885675-66-1 2-氯-6-(4-甲烷磺酰基-... | CAS号885698-97-5 2-氯-4-(4-吗啉)噻吩并... | CAS号885698-98-6 4-(6-(溴甲基)-2-氯噻...

Methyl 3-[(Aminocarbonyl)Amino]Thiophene-2-Carboxylate置于n-甲基吡咯烷酮,Sodium Hydroxide,三氯氧磷体系中,用 甲苯 用作溶剂,化学反应 4.0H,反应生成2,4-二氯噻吩并[3,2-D]嘧啶
参考文献:Synthesis And Antibacterial Activity Of Novel 4-{4-(Methylamino)Thieno[3,2-D]Pyrimidin-2-Yl}-Benzohydrazide Derivatives
标题:Synthesis And Antibacterial Activity Of Novel 4-{4-(Methylamino)Thieno[3,2-D]Pyrimidin-2-Yl}-Benzohydrazide Derivatives
摘要:A Series Of Novel 4-{4-(Methylamino)Thieno[3,2-D]Pyrimidin-2-Yl}Benzohydrazide Derivatives Were Synthesized And Evaluated For Their Antibacterial Activity. Most Of The Compounds Demonstrated High Activity Towards Escherichia Coli,Pseudomonas,Staphylococcus Aureus,And Bacillus. Structures Of All Synthesized Compounds Were Confirmed By Spectral Analysis.
Doi:10.1134/s1070363217060238

专利信息

专利号:US-2023399302-A1
优先权日:2020-10-29
标题:Process for the preparation of heteroaryl-substituted sulfur(vi) compounds
发明人：LOPCHUK JUSTIN M; SHULTZ ZACHARY P; SCATTOLIN THOMAS
权利人:H LEE MOFFITT CANCER CT & RES
摘要:The present disclosure provides processes for the synthesis of organic compounds, in particular processes for the synthesis of heteroaryl-substituted sulfur(VI) compounds by nucleophilic aromatic substitution.

专利号:US-9895374-B2
优先权日:2015-03-02
标 题:Thieno- and pyrrolopyrimidine analogues as anticancer agents and methods of use thereof
发明人：RADTKE KATHERINE L; TEMBURNIKAR KARTIK
权利人:UNIV MARYLAND
摘要:The present invention provides for the design and synthesis of halogenated thieno- and pyrrolopyrimidine compounds that exhibit cancer proliferation inhibitory activity and the use thereof for cancer treatment.

专利号:US-10646490-B2
优先权日:2015-03-02
标 题 :Thieno- and pyrrolopyrimidine analogues and prodrugs thereof as anticancer agents and methods of use thereof
发明人：RADTKE KATHERINE L
权利人:UNIV MARYLAND
摘要:The present invention provides for the design and synthesis of halogenated thieno- and pyrrolopyrimidine compounds and prodrugs thereof that exhibit cancer proliferation inhibitory activity and the use thereof for cancer treatment.

专利号:US-7648986-B2
优先权日:2002-01-10
标题:Substituted thieno[3,2-D]pyrimidines as Rho kinase inhibitors
发明人：NAGARATHNAM DHANAPALAN; KHIRE UDAY; ASGARI DAVOUD; SHAO JIANXING; LIU XIAO-GAO; WANG CHUNGUANG; HART BARRY; WEBER OLAF; LYNCH MARK; ZHANG LEI; WANG LEI
权利人:BAYER HEALTHCARE LLC
摘要:Disclosed are compounds and derivatives thereof their synthesis, and their use as Rho-kinase inhibitors. These compounds of the present invention are useful for inhibiting tumor growth, treating erectile dysfunction, and treating other indications mediated by Rho-kinase, e.g., coronary heart disease.

专利号:CN-106866327-A
优先权日:2017-03-13
标题 :A kind of methyl aryl sulfide compound and its synthesis method and application