CAS: 1458-01-1; Methyl 3,5-Diamino-6-Chloropyrazine-2-Carboxylate

相似化合物

4878-36-8 1458-03-3 1458-18-0

上下游产品

methanol amilorideN-Cyclohexylamino-3,5-diamino-6-chloropyrazine-2-carboxamide 3,5-diamino-6-chloro-pyrazinecarboxylic acid 2-methylhydrazide 3,5-diamino-6-chloro-pyrazine-2-carboxylic acid 3,5-diamino-6-chloro-pyrazine-2-carboxylic acid phenethylcarbamimidoyl-amide

甲醇,脒氯嗪 以 氯仿 用作溶剂,化学反应 17.0H,以60%的收率获得3,5-二氨基-6-氯吡嗪-2-羧酸甲酯
参考文献:Abbauprodukte Von Amiloridhydrochlorid
标题:Abbauprodukte Von Amiloridhydrochlorid
摘要:在ph4.6的醋酸盐缓冲液中加热氯化阿米洛利(1•hcl)会产生阿米洛利醋酸盐(1•acoh),吡嗪二胺6和酰基脲7.在dmf中回流加热1•hcl可以得到pteridinon 3.
Doi:10.3797/scipharm.Aut-04-10

专利信息

专利号:WO-2011156355-A1
优先权日:2010-06-09
标题 :Production method of phenyl guanidine salts and their intermediates
发明人：JOHNSON MICHAEL ROSS; KANG MYUNG-CHOL; BRAY BRIAN L; SCHNEIDER STEPHEN
权利人:KAINOS MEDICINE INC; JOHNSON MICHAEL ROSS; KANG MYUNG-CHOL; BRAY BRIAN L; SCHNEIDER STEPHEN
摘要:This invention relates to methods for producing phenyl guanidine salts having pharmacological activity, as well as to the identification and synthesis of compounds useful as intermediates for producing phenyl guanidine salts having pharmacological activity.

专利号:US-3948895-A
优先权日:1971-09-28
标题 :Synthesis of 3,5-diaminopyrazinoic acid from 3,5-diamino-2,6-dicyanopyrazine and intermediates
发明人：DONALD DENNIS S
权利人:DU PONT
摘要:An improved method for the preparation of 3,5-diaminopyrazinoic acid (which is useful for the manufacture of diuretics) is described. New compounds obtained in the process include 3,5-diamino-2,6-dicarbamoylpyrazine; 3.5-diamino-6-carbamoylpyrazinoic acid and 3,5-diamino-6-carbamoylpyrazine. The latter compounds are also useful as curing agents for epoxy resins.