CAS: 112522-64-2; 4-Acetamido-N-(2-Aminophenyl)Benzamide

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CAS号556-08-1 4-乙酰氨基苯甲酸 | CAS号95-54-5 邻苯二胺(OPD) | CAS号1353653-79-8 4-acetamido-N-(... | CAS号146651-75-4 N-B°C-1,2-亚苯基二胺 | CAS号88-74-4 2-硝基苯胺 | CAS号54614-93-6 2-硝基苯基氨基甲酸叔丁酯 | CAS号1075719-58-2 6-[2-(4-acetyla... | CAS号1075719-57-1 6-{4-[(2-(4-ace...

📜4-Acetamido-N-(2-Aminophenyl)Benzamide Trifluoroacetate Salt置于碳酸氢钠体系中,用 乙醇,水 用作溶剂,化学反应 1.5H,以92%的收率获得4-乙酰氨基-N-(2'-氨基苯基)-苯甲酰胺
参考文献: Novel Solid Forms Of Tacedinaline[fr] Nouvelles Formes Solides De Tacédinaline
标题: Novel Solid Forms Of Tacedinaline[fr] Nouvelles Formes Solides De Tacédinaline
摘要:揭示了tacedinaline(4-(乙酰氨基)-N-(2-氨基苯基)苯甲酰胺)的新型固体形式,包括结晶tacedinaline A,B和d形式,一种新型结晶tacedinaline Tfa盐,以及非晶态tacedinaline.还揭示了包含结晶tacedinaline A,B和d形式,新型结晶tacedinaline Tfa盐和/或非晶态tacedinaline的药物组合物,以及通过给予这些新型固体形式来治疗各种疾病的方法.

专利信息

专利号:US-8734846-B2
优先权日:2008-06-16
标 题 :Methods for the preparation of targeting agent functionalized diblock copolymers for use in fabrication of therapeutic targeted nanoparticles
发明人：ALI MIR M; HRKACH JEFF; ZALE STEPHEN E; ALVAREZ DE CIENFUEGOS LUIS
权利人:BIND BIOSCIENCES INC
摘要:This application provides nanoparticles and methods of making nanoparticles using pre-functionalized poly(ethylene glycol)(also referred to as PEG) as a macroinitiator for the synthesis of diblock copolymers. Ring opening polymerization yields the desired poly(ester)-poly (ethylene glycol)-targeting agent polymer that is used to impart targeting capability to therapeutic nanoparticles. This “polymerization fromâ€? approach typically employs precursors of the targeting agent wherein the reactivity of functional groups of the targeting agent is masked using protecting groups. Also described is a “coupling toâ€? that utilized the poly(ethylene glycol)-targeting agent conjugate where the targeting agent remains in its native un-protected form. This method uses “orthogonalâ€? chemistry that exhibit no cross reactivity towards functional groups typically found within targeting agents of interest.

专利号:US-2013035307-A1
优先权日:2010-01-26
标 题:Methods for treating or preventing the spread of cancer using semi-synthetic glycosaminoglycosan ethers
发明人：PRESTWICH GLENN D; KENNEDY THOMAS P
权利人:UNIV UTAH RES FOUND; PRESTWICH GLENN D; KENNEDY THOMAS P
摘要:Described herein are methods for the treatment and prevention of tumor metastasis using alkylated and fluoroalkylated semi-synthetic glycosaminoglycan ethers (“SAGEsâ€?). The synthesis of sulfated alkylated and fluoroalkylated SAGEs is also described.

专利号:US-2008214827-A1
优先权日:2004-02-03
标 题:Synthesis of Cyanoimino-Benzoimidazoles
发明人：GOEHRING R RICHARD; WHITEHEAD JOHN; SHAO BIN
权利人:EURO CELTIQUE SA
摘要:Disclosed in certain embodiments is a process for synthesizing a compound of formula (V) and salts thereof.

专利号:US-2019054057-A1
优先权日:2016-03-08
标题 :Immune boosting dietary compounds for disease control and prevention
发明人：ZHANG GUOLONG
权利人:THE BOARD OF REGENTS FOR OKLAHOMA STATE UNIV OFFICE OF INTELLECTUAL PROPERTY MANAGEMENT
摘要:Provided herein are small-molecule compounds and combinations thereof that enhance the synthesis of animal endogenous genus host defense peptides, which display potent antimicrobial and immunomodulatory activities. They thus represent alternatives to antibiotics for disease control and prevention for use in animals and humans. Examples of the small molecule compounds include histone deacetylase inhibitors, mono- and disaccharide sugars, cyclic adenosine monophosphate (cAMP) signaling agonists, and cyclooxygenase -2 (COX-2) inhibitors. Synergistic combinations include short-chain fatty acids, their chemical analogs or histone deacetylase inhibitors with other fatty acids, sugars, cAMP signaling agonists, and/or COX-2 inhibitors.

专利号:US-2015374859-A1
优先权日:2014-06-25
标 题 :Imaging compounds for tracking histone deacetylase inhibitor and synthesis method thereof
发明人：LI MING-HSIN
权利人:LI MING-HSIN
摘要:A synthesis method of labeling histone deacetylase inhibitor (HDAC inhibitors) SC027 with Gallium-67 or Gallium-68 radionuclide, wherein a labeled precursor DOTA-SC027 which comprises DOTA-NHS-ester (1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid-N-hydroxysuccinimide-ester) and HDACi-SC027 is prepared for the synthesis to label HDACi-SC027 with Gallium-67 or Gallium-68 radionuclide for producing imaging tracers for tracking the HDACi.

专利号:US-2024382626-A1
优先权日:2023-05-16
标题 :Irradiation amenable liposomal dye aggregates and methods of synthesis and use thereof
发明人：PORTER TYRONE; STERN NOAH; TUNNELL JAMES; SHRESTHA BINITA
权利人:UNIV TEXAS
摘要:The present invention provides lipid nanoparticles that are amenable to an irradiation at a wavelength at or above 850 nm, have an absorption peak from about 850 to 1100 nm wavelength, and comprise a high transition temperature lipid and a dye (e.g., a J-aggregate of a dye). In some embodiments, the dye (e.g., J-aggregate of the dye) is encapsulated in the lipid nanoparticle. In various embodiments, the present invention also relates to compositions comprising said lipid nanoparticles and methods of generating said lipid nanoparticles and compositions thereof. The present invention further relates to methods relating to the said lipid nanoparticles for imaging, detection, and treatment of diseases or disorders (e.g., phototherapy) in a subject.