CAS: 3061-91-4; (S)-2-((S)-2-Amino-3-Methylbutanamido)-3-(4-Hydroxyphenyl)Propanoic Acid

相似化合物

3061-88-9 3918-92-1 4306-24-5

上下游产品

CAS号3496-11-5 N-苄氧羰基-L-缬氨酸琥珀酰亚胺酯 | CAS号16652-64-5 O-苄基-L-酪氨酸 | CAS号13734-41-3 B°C-L-缬氨酸 | CAS号60-18-4 L-酪氨酸 | CAS号24601-74-9 (S)-4-异丙基恶唑-2,5-二酮 | CAS号862-26-0 Z-Val-Tyr-OH | CAS号75957-53-8 ENALAPRIL | CAS号53587-11-4 L-酪氨酸苄酯对甲苯磺酸盐 | CAS号15149-72-1 Cbz-val-try甲酯

📜苄氧羰基-缬氨酰-酪氨酸置于甲醇,Palladium On Activated Charcoal体系中,化学反应生成 L-缬氨酰基-L-酪氨酸
参考文献:合成具有val 5高血压素i(l-天冬酰胺基-L-精氨酰基-L-戊基-L-酪氨酰基-L-戊基-L-组氨酸-L-脯氨酰基-L-苯丙氨酰基-L-组氨酸-L-亮氨酸和l-天冬酰胺基-L-精氨酸-L-戊基-L-酪氨酰基-L-戊基-L-组氨酸-L-脯氨酰基-L-苯丙氨酰基-L-组氨酸-L-亮氨酸)
标题:合成具有val 5高血压素i(l-天冬酰胺基-L-精氨酰基-L-戊基-L-酪氨酰基-L-戊基-L-组氨酸-L-脯氨酰基-L-苯丙氨酰基-L-组氨酸-L-亮氨酸和l-天冬酰胺基-L-精氨酸-L-戊基-L-酪氨酰基-L-戊基-L-组氨酸-L-脯氨酰基-L-苯丙氨酰基-L-组氨酸-L-亮氨酸)
摘要:先前公开的具有val 5-高血压蛋白i氨基酸序列的十肽合成(4)已重复了几次.产物显示出高血压活性,与相应的八肽[val 5-高血压蛋白ii和val 5-高血压蛋白ii-Asp-β-酰胺(12)]相当.本文描述了产生最纯净的中间体和产物的合成方法.合成的val 5-高血压蛋白i和val 5的化学纯度很高通过逆流分布,纸色谱,元素分析和水解后的氨基酸测定来确定β-高血压蛋白i-Asp-β-酰胺.游离的结晶肽h•val-Tyr•oh(l-L),H•val-His•oh(l-L),H•val-Tyr-Val•oh(l 3),H•val-Tyr-Val-His .oh(l 4)和h.pro-Phe.oh(l-L)由合成中间体制备.
DOI:10.1002/hlca.19580410512

专利信息

专利号:US-5801047-A
优先权日:1992-11-25
标题:Method for making stable extracellular tyrosinase and synthesis of polyphenolic polymers therefrom
发明人：DELLA-CIOPPA GUY RICHARD; GARGER JR STEPHEN JOHN; HOLTZ RICHARD BARRY; MCCULLOCH MICHAEL JAY; SVERLOW GENADIE GLEB
权利人:BIOSOURCE TECH INC
摘要:A process for the in vitro production of chemically modified polyphenolic polymer (PPP). First, stable, highly active extracellular tyrosinase is produced from genetically transformed microorganism such as Streptomyces antibioticus. The tyrosinase is then incubated with a reaction substrate such as 1-tyrosine, hydrolyzed protein, or an oligopeptide in combination with 1-tyrosine. The ratio of the oligopeptide/tyrosine combination as well as variation in the concentration of tyrosinase can be used to modify the color, the molecular size, and the spectral absorbance properties of the PPP produced. Alternatively, or additionally, oxidants such as hydrogen peroxide or hypochlorite can be used to modify the color of the PPP, regardless of the method used to produce the PPP, and the PPP can subsequently be fractionated using molecular weight cut-off ultrafiltration. Organic solvents can also be used in the method of making PPP to produce PPPs having variable but reproducible physical properties.

专利号:US-11946086-B2
优先权日:2017-01-05
标题 :Gene involved in synthesis of cyclic peptide compound, method for producing cyclic peptide compound using the same, and transformant comprising the same
发明人：KUBO TAKASHI; MACHIDA MASAYUKI; UMEMURA MAIKO; ABE KEIETSU; YOSHIMI AKIRA; FUJIOKA TOMONORI; YAMAGUCHI Shigenari; KAWAI KIYOSHI
权利人:AIST; UNIV TOHOKU; KUMIAI CHEMICAL INDUSTRY CO
摘要:This invention is intended to identify a gene cluster involved in biosynthesis of a cyclic peptide compound produced by a filamentous fungus of the Curvularia species and to establish a system for synthesizing such cyclic peptide compound. The gene is composed of a first module to a tenth module and encodes a protein having activity of synthesizing a nonribosomal peptide constituting a basic peptide backbone of a cyclic peptide compound produced by a filamentous fungus of the Curvularia species.

专利号:US-6664282-B2
优先权日:1999-09-17
标 题:Synthesis of [3,5,7]-1H-imidazo [1,5-a]imidazol-2 (3H)- one compounds
发明人：ELABDELLAOUI HASSAN M; OSTRESH JOHN M; HOUGHTEN RICHARD A
权利人:TORREY PINES INST
摘要:Individual substituted [3,5,7]-1H-imidazo[1,5-a]imidazol-2(3H)-one compounds and their pharmaceutically-acceptable salts are disclosed, as are libraries of such compounds. Methods of preparing and using the libraries of compounds as well as individual compounds of the libraries are also disclosed.

专利号:CN-115626867-A
优先权日:2022-10-08
标 题:Preparation of a non-classical solid-phase synthesis carrier and its application in the synthesis of thymopentin

专利号:WO-9812201-A1
优先权日:1996-09-23
标题 :Phosphorylating reagents
发明人：GANI DAVID; HILLIER MARK; HORMOZDIARI PANTEA
权利人:UNIV ST ANDREWS; GANI DAVID; HILLIER MARK; HORMOZDIARI PANTEA
摘要:There is provided a phosphorylating reagent for phosphrylation of amino acids or compounds formed therefrom. The phosphorylating reagent is of utility in solution or solid-phase chemistry, and particularly for the solid-phase synthesis of phosphorylated peptides and combinational libraries of phosphorylated organic compounds. Also provided for is a method of phosphorylating oxygen, nitrogen and sulphur nucleophides, for example amino acid and peptides.

专利号:US-2022259634-A1
优先权日:2017-01-05
标题:Gene involved in synthesis of cyclic peptide compound, method for producing cyclic peptide compound using the same, and transformant comprising the same