CAS: 2360-45-4; 2-Propionylbenzoic Acid

上下游产品

phthalic anhydride diethylcadmium propionic acid anhydride (2-propionyl-phenyl)-glyoxylic acid4-ethyl-1(2H)-phthalazinone 3-ethyl-3-benzoyloxy-phthalide 1-(1-hydroxypropyl)-2-hydroxymethylbenzene 2-pivaloylbenzoic acid

📜3-Ethylidenephthalide置于potassium Hydroxide体系中,用 乙醇,水 用作溶剂,化学反应生成2-丙酰苯甲酸
参考文献:水转移加氢条件下2-酰基芳基羧酸酯的高效还原环化催化手性邻苯二甲酸酯的对映选择性合成
标题:水转移加氢条件下2-酰基芳基羧酸酯的高效还原环化催化手性邻苯二甲酸酯的对映选择性合成
摘要:发现了一种新的用于不对称转移氢化(ath)的二胺配体.发现2-酰基芳基羧酸盐的还原环化通过新的ru络合物催化的ath以及随后在水性条件下的原位内酯化而高度立体选择性地进行.它可以有效地获得对映体纯净形式的各种3-取代的邻苯二甲酸酯.
Doi:10.1021/ol901674K

专利信息

专利号:US-2004110228-A1
优先权日:2002-04-01
标 题:Combinatorial organic synthesis of unique biologically active compounds
发明人：MCALPINE SHELLI R; TAYLOR RACHEL E; BOLLA MEGAN L; SEGALL ANCA M
摘要:The invention provides a method for making a combinatorial library of cyclic compounds, such as Holliday junction-trapping compounds, comprising the steps of (a) obtaining a plurality of trimers according to the generic structure X 1- X 2- X 3 , wherein X 1 , X 2 and X 3 can be independently any naturally or nonnaturally occurring amino acids or peptidomimetics thereof; (b) optionally coupling a spacer S to the trimer at either end; (c) cyclizing two trimers or trimer-spacer conjugates in a head-to-tail orientation; thereby obtaining a combinatorial library of compounds, wherein the library does not include an unmodifed or naturally occurring Holliday Junction-trapping compounds. The invention additionally provides methods macrocyclic compounds that are synergimycin derivatives.