CAS: 115198-80-6; Tert-Butyl (Oxiran-2-Ylmethyl)Carbamate

相似化合物

161513-47-9 149057-20-5 14321-26-7

上下游产品

N-tert-butoxycarbonylprop-2-en-1-amine tert-butyl dicarbonatedi-tert-butyl dicarbonate tert-butyl N-(2,3-dihydroxypropyl)carbamate tert-butyl-3-chloro-2-hydroxypropylcarbamate5,14-dibenzyl-1,18-bis(tert-butoxycarbonyl)-3,16-dihydroxy-1,5,14,18-tetraaza°Ctadecane rac-1-(N-tert-Butoxycarbonylamino)-2-hydroxy-3-phenoxypropane -2,3-dihydroxypropane(S)-1-(tert-butoxycarbonyl)amino-2,3-dihydroxypropane -2,3-dihydroxypropane(R)-1-(tert-butoxycarbonyl)amino-2,3-dihydroxypropane

📜N-(2,3-二羟基丙基)氨基甲酸叔丁酯置于吡啶,甲基磺酰氯体系中,化学反应生成N-(2-环氧乙烷基甲基)氨基甲酸酯
参考文献:Macrocyclic Compound
标题:Macrocyclic Compound

专利信息

专利号:US-8877171-B2
优先权日:2010-02-03
标 题 :Polyanionic multivalent macromolecules for intracellular targeting of proliferation and protein synthesis
发明人：LICHA KAI; SCHIRNER MICHAEL; WELKER PIA; HAAG RAINER; WEINHART MARIE; PAULUS FLORIAN
权利人:LICHA KAI; SCHIRNER MICHAEL; WELKER PIA; HAAG RAINER; WEINHART MARIE; PAULUS FLORIAN; MIVENION GMBH
摘要:The present invention relates generally to methods and compositions for targeting of intracellular molecules involved in proliferation and protein synthesis of activated cells using polyanionic multivalent macromolecules. In particular aspect, multiple sulfate groups linked to polyol are specifically targeted to the cytoplasm and nucleus of proliferating and activated cells. The invention further comprises novel polyanionic macromolecular compounds and formulations.

专利号:WO-2013046211-A1
优先权日:2011-09-27
标 题 :Processes for the preparation of 5-chloro-n-({(5s)-2-oxo-3-[4-(3-oxo-4-morpholinyl) phenyl]-1,3-oxazolidin-5-yl}methyl)-2-thiophene-carboxamide and intermediates thereof
发明人：MOHAN RAO DODDA; KRISHNA REDDY PINGILI; VENKAT REDDY BUTHUKURI
权利人:SYMED LABS LTD; MOHAN RAO DODDA; KRISHNA REDDY PINGILI; VENKAT REDDY BUTHUKURI
摘要:TThe present invention provides processes for the preparation of 5-chloro-N-({(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-1,3-oxazolidin-5-yl}methyl)-2-thiophene-carboxamide (I) and intermediates thereof. Also provides novel intermediates and their use in the synthesis of oxazolidine derivatives.

专利号:US-8431714-B2
优先权日:2007-04-16
标题:Synthesis of drug conjugates via reaction with epoxide-containing linkers
发明人：MCKENNA CHARLES E; KASHEMIROV BORIS A; BALA JOY LYNN F
权利人:MCKENNA CHARLES E; KASHEMIROV BORIS A; BALA JOY LYNN F; UNIV SOUTHERN CALIFORNIA
摘要:The present invention relates to drug derivatives and linkers. The invention specifically relates to compounds and methods of phosphonates and linkers, that are useful as carriers for imaging agents and useful in the treatment of various bone diseases.

专利号:US-2008312440-A1
优先权日:2007-04-16
标 题:Synthesis of drug conjugates via reaction with epoxide-containing linkers

专利号:US-2005215801-A1
优先权日:2002-06-28
标 题 :Process for preparation of optically active 1-substituted amino-2,3-epoxypropanes, intermediates for synthesis thereof and process for preparation of the intermediates
发明人：KITAJIMA KUMI; NAGASHIMA NOBUO
权利人:KITAJIMA KUMI; NAGASHIMA NOBUO
摘要:The present invention provides an industrial process for effectively and advantageously preparing optically active 1-substituted amino-2,3-epoxypropanes useful as intermediates for preparing agricultural chemicals and medical products from optically active 1-substituted amino-2,3-propanediols used as raw materials. The present invention also provides useful intermediates. Specifically, an optically active 1-substituted amino-2,3-propanediol (1) is reacted with an orthoacid ester (2) or thionyl chloride (3) to produce a cyclic optically active compound (4), and then a compound (5) containing a halogen atom is prepared by reaction with a ring-opening reaction agent having an ability to introduce a halogen atom X. Finally, an optical active 1-substituted amino-2,3-epoxypropane is prepared by ring-closure reaction in the presence of a base.

专利号:US-2013203998-A1
优先权日:2007-04-16
标题:Synthesis of Drug Conjugates Via Reaction With Epoxide-Containing Linkers