CAS: 931-50-0; Cyclohexylmagnesium Bromide

• 英文名称Cyclohexylmagnesium Bromide
• 中文名称环己基溴化镁
• 其它别名Cyclohexylmagnesiumbromide (6CI); Bromo(cyclohexyl)magnesium
• CAS编号931-50-0
• MFCD编号:MFCD01321152
• 分子式:C6H11BrMg
• 分子量:187.36
• 产品CID: 1970128
• 产品分类有机原料 → 有机金属类化合物 → 有机镁

• 相似结构搜索
• InChIKey: GFTXWCQFWLOXAT-UHFFFAOYSA-M
• SJUKXVKSGSJVTJ-UHFFFAOYSA-M…
• 计算化学: 氢键受体数*氢键供体数0.0可旋转键数1.0

物理性质

• 闪点-17 °C (THF)
• LogP:3.1339
• 外观形态液体
• 储存条件存放于惰性气体之中;避免空气,湿气(分解)

MSDS等安全信息

• GHS符号GHS02,GHS05,GHS07,GHS08
• 警示词Danger
• 危险描述H225-H302-H314-H335-H371-H372
• 防范说明P210-P233-P240-P241+P242+P243-P260-P264-P270-P271-P280-P301+P330+P331+P310-P303+P361+P353+P310+P363-P304+P340+P310-P305+P351+P338+P310-P308+P311-P403+P233-P405-P501
• 危险等级3/8
• UN编号1993
• 危险品标志Xi
• 包装等级II
• 安全声明16-29-33
• 危险类别码11-19-36/37/38-36/37-14

上下游产品

合成工艺路线路线简述

• 108-85-0 = 931-50-0
  反应条件:1.1 Reagents: Magnesium Solvents: Tetrahydrofuran; Reflux
  标题:Probing The Delicate Balance Between Pauli Repulsion And London Dispersion With Triphenylmethyl Derivatives
  作者:Roesel,Soeren; Becker,Jonathan; Allen,Wesley D.; Schreiner,Peter R.
  参考文献:Journal Of The American Chemical Society 日期:2018 卷标:140(43) 页码:14421-14432]
  
  108-85-0 = 931-50-0
  反应条件:1.1 Reagents: Magnesium Solvents: Tetrahydrofuran; Rt
  标题:Mechanochemistry-Amended Barbier Reaction As An Expedient Alternative To Grignard Synthesis
  作者:Varma Nallaparaju,Jagadeesh; Nikonovich,Tatsiana; Jarg,Tatsiana; Merzhyievskyi,Danylo; Aav,Riina; Et Al
  参考文献:Angewandte Chemie 日期:2023 卷标:62(39)]
  
  108-85-0 = 931-50-0
  反应条件:1.1 Reagents: Magnesium Solvents: Diethyl Ether,Tetrahydrofuran; Rt; Rt -> 50 °C
  标题:Enantioselective Synthesis Of Chiral Cyclic Hydrazines By Ni-Catalyzed Asymmetric Hydrogenation
  作者:Wang,Siwei; Xie,Chaochao; Zhu,Yu; Zi,Guofu; Zhang,Zhanbin; Et Al
  参考文献:Organic Letters 日期:2023 卷标:25(20) 页码:3644-3648]
  
  108-85-0 = 931-50-0
  反应条件:1.1 Reagents: Magnesium Solvents: Diethyl Ether; Rt -> Reflux; 30 Min,Reflux; 1 H,Reflux
  标题:Rhodium-Catalyzed Intramolecular Cyclopropanation Of Trifluoromethyl- And Pentafluorosulfanyl-Substituted Allylic Cyanodiazoacetates
  作者:Peyrical,Lauriane C.; Berger,Marie-Rose Ouellet-Du; Boucher,Maxim; Birepinte,Melodie; Paquin,Jean-Francois; Et Al
  参考文献:Organic Letters 日期:2023 卷标:25(14) 页码:2487-2491]
  
  108-85-0 = 931-50-0
  反应条件:1.1 Reagents: 1,2-Dibromoethane,Magnesium Solvents: Tetrahydrofuran; Heated1.2 Solvents: Tetrahydrofuran; Heated; 1 H,Rt
  标题:A Sulfoxide Reagent For One-Pot,Three-Component Syntheses Of Sulfoxides And Sulfinamides
  作者:Saito,Fumito
  参考文献:Angewandte Chemie 日期:2022 卷标:61(52)]
  
  108-85-0 = 931-50-0
  反应条件:1.1 Reagents: Magnesium Catalysts: Iodine Solvents: Tetrahydrofuran; Rt; 20 Min,Reflux; 6 H,Reflux
  标题:Enantioselective Construction Of Sila-Bicyclo[3.2.1] Scaffolds Bearing Both Carbon- And Silicon-Stereocenters
  作者:Yin,Kai-Lin; Zhao,Shuang; Qin,Ying; Chen,Shu-Han; Li,Bo; Et Al
  参考文献:Acs Catalysis 日期:2022 卷标:12(22) 页码:13999-14005]
  
  108-85-0 = 931-50-0
  反应条件:1.1 Reagents: Magnesium Catalysts: 1,2-Dibromoethane Solvents: Tetrahydrofuran; Heated; 1 H,Rt
  标题:A Sulfoxide Reagent For One-Pot,Three-Component Syntheses Of Sulfoxides And Sulfinamides
  作者:Saito,Fumito
  参考文献:Chemrxiv 日期:2022 卷标:1 页码:1-11]
  
  108-85-0 = 931-50-0
  反应条件:1.1 Reagents: Magnesium Catalysts: Iodine Solvents: Tetrahydrofuran; Rt; 1 Min,Rt1.2 Reagents: Water
  标题:Stereospecific Csp3 Suzuki-Miyaura Cross-Coupling That Evades β-Oxygen Elimination
  作者:Laporte,Antonio J.; Shi,Yao; Hein,Jason E.; Burke,Martin D.
  参考文献:Acs Catalysis 日期:2022 卷标:12(17) 页码:10905-10912]
  
  108-85-0 = 931-50-0
  反应条件:1.1 Reagents: Magnesium Catalysts: 1,2-Dibromoethane Solvents: Tetrahydrofuran; 1.5 H,Rt1.2 Solvents: Tetrahydrofuran; 1 H,Rt; 2 H,Rt
  标题:Synthesis Of 1- And 1,2-Substituted Cyclopropylamines From Ketone Homoenolates
  作者:West,Michael S.; Pia,Julia E.; Rousseaux,Sophie A. L.
  参考文献:Organic Letters 日期:2022 卷标:24(32) 页码:5869-5873]
  
  108-85-0 = 931-50-0
  反应条件:1.1 Reagents: Magnesium Solvents: Tetrahydrofuran; Rt; Rt -> 50 °C
  标题:Nickel-Catalyzed Asymmetric Hydrogenation Of γ-Keto Acids,Esters,And Amides To Chiral γ-Lactones And γ-Hydroxy Acid Derivatives
  作者:Xiao,Guiying; Xie,Chaochao; Guo,Qianling; Zi,Guofu; Hou,Guohua; Et Al
  参考文献:Organic Letters 日期:2022 卷标:24(14) 页码:2722-2727]
  
  108-85-0 = 931-50-0
  反应条件:1.1 Reagents: Magnesium Solvents: 1,2-Dibromoethane,Tetrahydrofuran; Rt; 1 H,40 °C
  标题:Asymmetric Synthesis Of Chiral Sulfimides Through The O-Alkylation Of Enantioenriched Sulfinamides And Addition Of Carbon Nucleophiles
  作者:Tsuzuki,Saori; Kano,Taichi
  参考文献:Angewandte Chemie 日期:2023 卷标:62(16)]
  
  108-85-0 = 931-50-0
  反应条件:1.1 Reagents: Magnesium Catalysts: Iodine Solvents: Tetrahydrofuran; Rt; 3 H,Rt
  标题:Synthesis Of Sulfur-Containing Oxindoles By Photoinduced Alkene Difunctionalization Via Sulfur 1,2-Relocation
  作者:Lu,Cong; Chen,Rui; Wang,Rui; Jing,Dong; Zheng,Ke
  参考文献:Organic Letters 日期:2023 卷标:25(5) 页码:750-755]
  
  108-85-0 = 931-50-0
  反应条件:1.1 Reagents: Magnesium Solvents: Tetrahydrofuran
  标题:The Comparison Of Self-Assembling Behaviour Of Phenyl Biphenylcarboxylate And Biphenyl Benzoate Compounds With The Different Length And Shape Of Chiral Terminal Chain
  作者:Strojwas,Katarzyna; Dabrowski,Roman; Drzewinski,Witold; Szarek,Michal; Bubnov,Alexej; Et Al
  参考文献:Journal Of Molecular Liquids 日期:2023 卷标:369]
  
  108-85-0 = 931-50-0
  反应条件:1.1 Reagents: Magnesium,Iodine Solvents: Tetrahydrofuran; Heated; 10 °C; Overnight,Rt
  标题:Iron-Catalyzed Cross-Coupling Of Thioesters And Organomanganese Reagents
  作者:Geiger,Valentin Jacob; Lefevre,Guillaume; Fleischer,Ivana
  参考文献:Chemistry - A European Journal 日期:2022 卷标:28(62)]
  
  108-85-0 = 931-50-0
  反应条件:1.1 Reagents: Magnesium
  标题:Visible Light-Induced N-Radical 5-Exo/6-Endo Cyclization Of Alkenyl Amides: Facile Access To Isoindolinones/isoquinolinones
  作者:Lei,Zhen-Yao; Hu,Kui; He,Yuan-Xiang; Geng,Shu; Chen,Li-Na; Et Al
  参考文献:Organic & Biomolecular Chemistry 日期:2022 卷标:20(12) 页码:2397-2401]
  
  108-85-0 = 931-50-0
  反应条件:1.1 Reagents: Magnesium,Iodine Solvents: Tetrahydrofuran; 70 °C; 2 H,70 °C
  标题:Method For Preparing Di(1-Adamantyl) Cycloalkylphosphine Ligand By Diborane Treatment
  参考文献:China]
  
  108-85-0 = 931-50-0
  反应条件:1.1 Reagents: Magnesium
  标题:Clarification On The Reactivity Of Diaryl Diselenides Toward Hexacyclohexyldilead Under Light
  作者:Hung,Vu Thai; Tran,Cong Chi; Yamamoto,Yuki; Kodama,Shintaro; Nomoto,Akihiro; Et Al
  参考文献:Molecules 日期:2021 卷标:26(20)]
  
  108-85-0 = 931-50-0
  反应条件:1.1 Reagents: Magnesium
  标题:Benzylamine Derivatives Prepared For Skin Lightening
  参考文献:World Intellectual Property Organization]
  
  108-85-0 = 931-50-0
  反应条件:1.1 Reagents: Magnesium Catalysts: Iodine Solvents: Tetrahydrofuran; Heated; 1 - 2 H,Heated
  标题:A Facile And Practical Preparation Of P-Chiral Phosphine Oxides
  作者:Xu,Ronghua; Gao,Zhenhua; Yu,Yiteng; Tang,Yehua; Tian,Duanshuai; Et Al
  参考文献:Chemical Communications (Cambridge 日期:2021 卷标:57(27) 页码:3335-3338]
  
  108-85-0 = 931-50-0
  反应条件:1.1 Reagents: Magnesium,Iodine Solvents: Diethyl Ether; Rt; Rt -> Reflux; 30 H,Reflux
  标题:Degradable Photoresist Resin Monomer From Trimethylbicyclo[2.2.2]Octanedione And Synthesis Method Thereof
  参考文献:China

专利信息

其他信息查阅

• ➥ 象形图和危险代码
• ➥ 防范代码详解
• ➥ 危险代码说明
• ➥ Globally Harmonized System
• ➥ REACH监管