CAS: 88474-31-1; 4-Chloro-6-Methoxy-2-Methylpyrimidin-5-Amine
该化合物是六人组成的热循环环环状结构,含有1号阵地和3号阵地的两个氮原子. 该化合物具有4号位置的替代成分,6号位置的甲基氧基(OCH3),以及2号位置的甲基(-CH3),这些替代成分有助于其化学反应和潜在的生物活动.氨基生物组(-NH2)在5号位置的存在表明,它可以参与各种化学反应,包括核球类代用和组合反应.该化合物可能具有诸如极地溶剂溶解性等特性,其结构表明在制药或农用化学化学品中的潜在用途,特别是在研制抗微生物或草药性化合物方面.与许多亚米丁衍生物的特性,其具体相互作用和影响取决于其使用环境和其他功能组的存在.
- 英文名称4-Chloro-6-Methoxy-2-Methylpyrimidin-5-Amine
- 中文名称4-氯-6-甲氧基-2-甲基嘧啶-5-胺
- IUPAC名称4-chloro-6-methoxy-2-methylpyrimidin-5-amine
- 其它别名4-氯-6-甲氧基-2-甲基嘧啶-5-胺; 2-甲基-4-甲氧基-5-氨基-6-氯嘧啶; 5-Amino-4-Chloro-6-Methoxy-2-Methylpyrimidine
- CAS编号88474-31-1
- MFCD编号:MFCD01837887
- 分子式:C6H8ClN3O分子量:173.6
- 产品CID: 1895590
- 产品分类有机原料→分子砌块→芳杂环类化合物→嘧啶类化合物
相似化合物
60331-15-9 15846-19-2 53135-45-8物理性质
MSDS等安全信息
上下游产品
CAS号39906-04-2 2-甲基-4,6-二氯-5-氨基嘧啶 | CAS号124-41-4 甲醇钠 | CAS号67-56-1 甲醇 | CAS号13162-43-1 2-甲基-4,6-二氯-5-硝基嘧啶 | CAS号60331-15-9 2-甲基-4-甲氧基-5-硝基... | CAS号88474-33-3 5-氯-1H-[1,2,3]三... | CAS号53135-45-8 4-甲氧基-2-甲基嘧啶-5-胺合成工艺路线路线简述
- 13162-43-1 = 88474-31-1
反应条件:1.1 Catalysts: Acetic Acid2.1 -
标题:Synthesis Of 4-Chloro-1,2,3-Triazole Derivatives By The Diazotization Of 6-Substituted 5-Amino-4-Chloropyrimidines
作者:Nemeryuk,M. P.; Et Al
参考文献:Khimiya Geterotsiklicheskikh Soedinenii 日期:1983 卷标:(10) 页码:1398-400]
39906-04-2 = 88474-31-1 [标题:Reaction Conditions
标题:Synthesis Of 4-Chloro-1,2,3-Triazole Derivatives By The Diazotization Of 6-Substituted 5-Amino-4-Chloropyrimidines
作者:Nemeryuk,M. P.; Et Al
参考文献:Khimiya Geterotsiklicheskikh Soedinenii 日期:1983 卷标:(10) 页码:1398-400
📜2-甲基-4,6-二氯-5-硝基嘧啶置于水,锌体系中,化学反应生成 4-氯-6-甲氧基-2-甲基嘧啶-5-胺
参考文献:合成氨基5-嘧啶及磺胺类化合物的对应物
标题:合成氨基5-嘧啶及磺胺类化合物的对应物
摘要:通过各种方法合成被烷基和烷氧基取代的5-氨基嘧啶.由它们制得的一些磺酰苯胺具有强烈而持久的化学治疗作用.
DOI:10.1002/hlca.19580410635
海关参考信息
- 2905110000-甲醇
2909199090-其他醚及其衍生物 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:US-9469614-B2
优先权日:2011-10-27
标 题:Synthesis of triazolopyrimidine compounds
发明人：ZUPANCIC BORUT; MARAS NENAD; STERK DAMJAN
权利人:LEK PHARMACEUTICALS
摘要:The present invention relates to the field of organic synthesis and describes the synthesis of specific triazolopyrimidine compounds and intermediates thereof as well as related derivatives.
专利号:WO-2015011010-A1
优先权日:2013-07-26
标 题:Synthesis of substituted aminopyrimidines
发明人：ACQUASALIENTE MAURIZIO; LAGERWEIJ GERT; DESHPANDE MAHENDRA; SHAH RAJENDRA
权利人:ABBOTT HEALTHCARE PRODUCTS BV; ABBOTT LAB
摘要:The present invention relates to a novel process for the manufacture of certain substituted aminopyrimidines having Formula (I) or a tautomer or salt thereof, wherein R 1 is selected from hydrogen, halogen, C 1-4 alkoxy, C 1-4 alklthio, C 1-4 alkyl, C 3-5 cycloalkyl, for example R1 is halogen such as chloro; R2 is C 1-4 alkyl, for example methyl, ethyl, i-propyl, n-propyl or butyl (any isomer), such as methyl; and R3 is selected from hydrogen, C 1-4 alkoxy, C 1-4 alkylthio, C 1-4 alkyl, C 3-5 cycloalkyl, for example C 1-4 alkyl such as methyl, ethyl, i-propyl, n-propyl or butyl (any isomer), for example methyl; crystalline forms thereof as well as chemical intermediates suitable for use in performing the process.
专利号:US-2014256747-A1
优先权日:2011-10-27
标 题 :Synthesis of Triazolopyrimidine Compounds
专利号:EP-2829540-A1
优先权日:2013-07-26
标 题 :Synthesis of substituted aminopyridines
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
合成参考文献
参考文献:10.1007/bf00505769
摘要:Nemeryuk MP, Sedov AL, Křepelka I, Beneš Y, Safonova TS. Synthesis of 4-chloro-1,2,3-triazole derivatives by diazotization of 6-substituted 5-amino-4-chloropyrimidines. Chemistry of Heterocyclic Compounds. 1983 Oct;19(10):1113–5. doi: 10.1007/bf00505769.
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