📜乙腈置于三氟甲磺酸酐体系中,用 二氯甲烷 作为反应溶剂,化学反应 12.0H,以89%的收率获得产物2,4,6-三甲基-1,3,5-三嗪 参考文献:A Practical And Easy Synthesis Of 2,4,6-Trisubstituted-S-Triazines 标题:A Practical And Easy Synthesis Of 2,4,6-Trisubstituted-S-Triazines 摘要:研究发现,在温和的条件下,三氟酸酐能有效地使二烷基氰酰胺发生环三聚反应.同样的反应也可用于芳基腈和硫氰酸盐. DOI:10.1055/s-2004-815927
专利信息
专利号:US-9738647-B2 优先权日:2009-12-24 标题:Methods for the synthesis of polycyclic guanidine compounds 发明人:GRIDNEV ALEXEI 权利人:NOVOMER INC; SAUDI ARAMCO TECH CO 摘要:The present invention provides methods for the synthesis of polycyclic guanidine compounds. In certain embodiments, provided methods include the step of contacting a described reagent with a triamine compound to provide a polycyclic guanidine compound.
专利号:US-2016168138-A1 优先权日:2013-07-15 标题:Process for the preparation of suvorexant and intermediates useful in the synthesis of suvorexant 发明人:IQBAL JAVED; DAHANUKAR VILAS HARESHWAR; ORUGANTI SRINIVAS; KANDAGATLA BHASKAR 权利人:REDDY S LAB LIMTED DR 摘要:A novel processes for the preparation of suvorexant (formula I), its related compounds and its intermediates that are simple, economical and commercially viable. (I)
专利号:US-6069277-A 优先权日:1995-05-12 标 题 :Amination of electrophilic aromatic compounds by vicarious nucleophilic substitution 发明人:MITCHELL ALEXANDER R; PAGORIA PHILIP F; SCHMIDT ROBERT D 权利人:UNIV CALIFORNIA 摘要:The present invention relates to a process to aminate electrophilic aromatic compounds by vicarious nucleophilic substitution of hydrogen using quaternary hydrazinium salts. The use of trialkylhydrazinium halide, e.g., trimethylhydrazinium iodide, as well as hydroxylamine, alkoxylamines, and 4-amino-1,2,4-triazole to produce aminated aromatic structures, such as 1,3-diamino-2,4,6-trinitrobenzene (DATB), 1,3,5-triamino-2,4,6-trinitrobenzene (TATB) and 3,5-diamino-2,4,6-trinitrotoluene (DATNT), is described. DATB and TATB are useful insensitive high explosives. TATB is also used for the preparation of benzenehexamine, a starting material for the synthesis of novel materials (optical imaging devices, liquid crystals, ferromagnetic compounds).
专利号:US-2007098676-A1 优先权日:2005-08-10 标 题 :Functionally diverse macromolecules and their synthesis 发明人:SIMANEK ERIC E; HOLLINK EMILY 权利人:SIMANEK ERIC E; HOLLINK EMILY 摘要:Functionally diverse macromolecules and synthetic routes for obtaining the same are disclosed. In certain embodiments, the synthesis proceeds in a divergent manner. In other embodiments, the routes rely on the differential reactivity of monomeric electrophilic triazine building blocks that display protected or unprotected groups. This diversity permits the facile introduction of a variety of diversity groups at multiple positions of these macromolecules, thereby setting the stage for further generational growth of the macromolecule and/or incorporation of other diversity groups such as biocompatible targeting groups.
专利号:US-2007041933-A1 优先权日:2005-08-10 标题:Functionally Diverse Macromolecules and Their Synthesis 发明人:SIMANEK ERIC E; HOLLINK EMILY 权利人:SIMANEK ERIC E; HOLLINK EMILY 摘要:Functionally diverse macromolecules and synthetic routes for obtaining the same are disclosed. In certain embodiments, the synthesis proceeds in a divergent manner. In other embodiments, the routes rely on the differential reactivity of monomeric electrophilic triazine building blocks that display protected or unprotected groups. This diversity permits the facile introduction of a variety of diversity groups at multiple positions of these macromolecules, thereby setting the stage for further generational growth of the macromolecule and/or incorporation of other diversity groups such as biocompatible targeting groups.
专利号:US-11685852-B2 优先权日:2020-09-03 标 题 :Reservoir drilling fluids consist of cationic heterocyclic polymers, synthesis, formulation, and applications 发明人:PATEL HASMUKH A; THAEMLITZ CARL 权利人:ARAMCO SERVICES CO 摘要:A wellbore fluid may include a base fluid and at least one cationic heterocyclic polymer in an amount effective to increase a viscosity of the base fluid, the cationic heterocyclic polymer includes at least two distinct cyclic monomers, at least one of which has at least two heteroatoms in the cyclic structure. A method of drilling a wellbore may introduce such wellbore fluid into the wellbore. A method of producing a cationic heterocyclic polymer may include reacting, in a solvent selected from the group that includes tetrahydrofuran, dioxane, dichloromethane, alcoholic solvents, chlorinated solvents, aromatic hydrocarbon solvents, or mixture thereof, at least two distinct cyclic monomers, at least one of which has at least two heteroatoms in the cyclic structure.