CAS: 694-85-9; 1-Methylpyridin-2(1H)-One

该化合物是一种有机化合物,其特点是带有一个甲基组和碳基组的环结构;在室温下,它是一种无色的黄色的黄色液体,具有一种独特的芳香味;这种化合物在水和有机溶剂中溶解,使其具有多种用途;其分子式为C6H7NO,其分子重量约为111.13g/mol.1-Meg-2,2(H)-pyridina,其作用是溶剂和药物和农用化学品合成的中间体.此外,它可以参与各种化学反应,包括核糖分泌替代和凝聚反应,因为有氮原子在环中存在,因此这种化合物的特性,如沸点和密度,可以因环境条件和纯度而变化.安全数据表明,应该谨慎地处理,因为接触时可能会引起皮肤或皮肤刺激.

结构式图片

相似化合物

1753-62-4 889865-47-8 214342-63-9

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上下游产品

CAS号142-08-5 2-羟基吡啶 | CAS号74-88-4 碘甲烷 | CAS号2044-27-1 2(1H)-Pyridinet... | CAS号96-54-8 N-甲基吡咯 | CAS号7440-44-0 活性炭 | CAS号110-94-1 戊二酸 | CAS号1719-57-9 氯甲基二甲基氯硅烷 | CAS号1628-89-3 2-甲氧基吡啶 | CAS号61985-23-7 甲基1H-咪唑-1-羧酸甲酯 | CAS号23353-96-0 2(1H)-pyridone | CAS号32896-90-5 1-甲基-5-硝基-2(1H)-吡啶酮 | CAS号14150-94-8 1-甲基-3,5-二硝基-1H... | CAS号4930-98-7 2-肼吡啶 | CAS号51173-06-9 5-氟-N-甲基-2-吡啶酮 | CAS号19848-72-7 N-(propan-2-yli... | CAS号19848-64-7 N-(1-phenylethy... | CAS号21382-30-9 5-(methylamino)... | CAS号26148-42-5 Phenol,2-(2-pyr... | CAS号81971-39-3 1-甲基-5-溴吡啶-2(1H)-酮 | CAS号81971-38-2 3-溴-1-甲基-2-吡啶酮

合成工艺路线路线简述

    1-甲基吡啶-2-硫酮置于sodium Hydroxide,Copper(L) Chloride体系中,用 水,乙腈 作为反应溶剂,化学反应 0.33H,以96%的收率获得产物1-甲基-2-吡啶酮
    参考文献:使用cucl和naoh将硫代羰基转化为羰基
    标题:使用cucl和naoh将硫代羰基转化为羰基
    摘要:描述了一种简单有效的方法,用于将硫代羰基迅速温和地转化为羰基.
    DOI:10.1016/s0040-4039(00)83914-3

    海关参考信息

    专利信息


    专利号:US-9469614-B2
    优先权日:2011-10-27
    标 题:Synthesis of triazolopyrimidine compounds
    发明人:ZUPANCIC BORUT; MARAS NENAD; STERK DAMJAN
    权利人:LEK PHARMACEUTICALS
    摘要:The present invention relates to the field of organic synthesis and describes the synthesis of specific triazolopyrimidine compounds and intermediates thereof as well as related derivatives.

    专利号:EP-2586773-A1
    优先权日:2011-10-27
    标题 :Synthesis of Triazolopyrimidine Compounds
    权利人:LEK PHARMACEUTICALS
    摘要:The present invention relates to the field of organic synthesis and describes the synthesis of specific triazolopyrimidine compounds and intermediates thereof as well as related derivatives.

    专利号:US-7605290-B2
    优先权日:2006-07-26
    标题 :Processes for the synthesis of O-desmethylvenlafaxine
    发明人:NIDDAM-HILDESHEIM VALERIE; SHENKAR NATALIA; SHACHAN-TOV SHARONA
    权利人:TEVA PHARMA
    摘要:The present invention describes processes for the preparation of O-desmethylvenlafaxine and tridesmethylvenlafaxine, which may be used as an intermediate in preparing O-desmethylvenlafaxine.

    专利号:US-2009069601-A1
    优先权日:2006-07-26
    标题:Processes for the synthesis of O-desmethylvenlafaxine
    发明人:NIDDAM-HILDESHEIM VALERIE; NIDAM TAMAR; DOLITZKY BEN-ZION
    权利人:NIDDAM-HILDESHEIM VALERIE; NIDAM TAMAR; DOLITZKY BEN-ZION
    摘要:The present invention describes processes for the preparation of O-desmethylvenlafaxine and tridesmethylvenlafaxine, which may be used as an intermediate in preparing O-desmethylvenlafaxine.

    专利号:US-5215997-A
    优先权日:1985-09-11
    标题:Synthesis of beta-lactam compounds
    发明人:HUNGERBUEHLER ERNST; KALVODA JAROSLAV
    权利人:CIBA GEIGY CORP
    摘要:The invention relates to an improved process for the preparation of compounds of formula ##STR1## or salts thereof, starting from compounds of formulae ##STR2## via compounds of formulae ##STR3## in which compounds R 1 is hydrogen or lower alkyl, R 2 is an organic radical which may carry a functional group which may be protected by a customary protective group R 2 o , R 3 is hydrogen or a customary carboxyl protective group R 3 o , W is a group which can be replaced by a thiocarboxylic acid radical of formula III, and Z is oxygen or sulfur.

    专利号:US-2008221356-A1
    优先权日:2006-07-26
    标题:Processes for the synthesis of O-desmethylvenlafaxine
    发明人:NIDDAM-HILDESHEIM VALERIE; NIDAM TAMAR; DOLITZKY BEN-ZION
    权利人:NIDDAM-HILDESHEIM VALERIE; NIDAM TAMAR; DOLITZKY BEN-ZION
    摘要:The present invention describes processes for the preparation of O-desmethylvenlafaxine and tridesmethylvenlafaxine, which may be used as an intermediate in preparing O-desmethylvenlafaxine.
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    主要参考文献

    [参考文献]: Maryam Goudarzi, Et Al. The Effect Of Low Dose Rate On Metabolomic Response To Radiation In Mice. Radiat Environ Biophys. 2014 Nov;53(4):645-57.

    合成参考文献


    摘要:Spitzner, D., Science of Synthesis Knowledge Updates, (2016) 1, 285.
    摘要:Nakao, Y., Science of Synthesis: Catalytic Transformations via CH Activation, (2015) 1, 343.
    摘要:Nakao, Y., Science of Synthesis: Catalytic Transformations via CH Activation, (2015) 1, 397.
    摘要:Nakao, Y., Science of Synthesis: Special Topics, (2022) 1, 566.
    摘要:Journal of Reproduction and Fertility., 48(371), 1976 []
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