CAS: 6779-09-5; Ethylphosphonic Acid

该化合物是一种有机磷磷化合物,其特征是存在磷酸功能组,它看起来无色可粉黄,在水中可溶解,在各种应用中有用.分子式为C2H7O3P,表明它含有碳,氢,氧和磷,乙酰磷酸因其作为发泡剂的能力而闻名,并经常用于磷酸和磷酸衍生物合成中度酸,典型的磷酸,可参与各种化学反应,包括酯化和恐吓.此外,它作为植物生长调节器和阻燃剂生产中也有应用.安全考虑包括谨慎处理,因为它可能刺激皮肤和眼睛.

结构式图片

欧盟法规

ECHA物质ECHA物质C&L通报REACH预注册

上下游产品

ethyl bromide ethyl phosphine ethylphosphinic acid ethylphosphonic acid diethyl esterEthylphosphonic dichloride ethane ethene β-Hydroxyethanphosphonsaeure

合成工艺路线路线简述

    乙基膦置于硝酸体系中,化学反应生成 乙基磷酸
    参考文献:Hofmann,A.W.,Chemische Berichte,1872,Vol. 5,P. 105
    标题:Hofmann,A.W.,Chemische Berichte,1872,Vol. 5,P. 105

    海关参考信息

    专利信息


    专利号:US-6133409-A
    优先权日:1996-12-19
    标 题:Process for the solid phase synthesis of aldehyde, ketone, oxime, amine, hydroxamic acid and αβ-unsaturated carboxylic acid and aldehyde compounds
    发明人:SALVINO JOSEPH M; MORTON GEORGE C; MASON HELEN J; LABAUDINIERE RICHARD F
    权利人:AVENTIS PHARM PROD INC
    摘要:This invention is directed to a process for the solid phase synthesis of aldehyde, ketone, oxime, amine, hydroxamic acid and alpha , beta -unsaturated carboxylic acid and aldehyde compounds and to polymeric hydroxylamine resin compounds useful therefor.

    专利号:US-10464958-B2
    优先权日:2012-07-17
    标题 :Method for the synthesis of alpha-aminoalkylenephosphonic acid
    发明人:NOTTE PATRICK; COGELS SAMUEL; BURCK SEBASTIAN
    权利人:MONSANTO TECHNOLOGY LLC
    摘要:The present invention is related to a new method for the synthesis of alpha-aminoalkylenephosphonic acid or its phosphonate esters comprising the steps of forming a reaction mixture by mixing a P—O—P anhydride moiety comprising compound, having one P-atom at the oxidation state (+III) and the other P-atom at the oxidation state (+III) or (+V), an aminoalkanecarboxylic acid and an acid catalyst, wherein said reaction mixture comprises an equivalent ratio of alpha-aminoalkylene carboxylic acid to P—O—P anhydride moieties of at least 0.2, and recovering the resulting alpha-aminoalkylene phosphonic acid compound or an ester thereof from the reaction mixture.

    专利号:US-4092316-A
    优先权日:1975-02-03
    标题:Synthesis of C-alkyl-triethylenediamines
    发明人:NIEH EDWARD C Y
    权利人:TEXACO DEVELOPMENT CORP
    摘要:A liquid phase synthesis of C-alkyl-triethylenediamines involves heating to elevated temperatures of from about 200° C to 300° C a suitable N-(2-hydroxyalkyl) piperazine feedstock in the presence of a catalytic amount of a pentavalent acidic phosphorus compound and then recovering the C-alkyl-triethylenediamine product from the resulting reaction product mixture.

    专利号:WO-2008150031-A1
    优先权日:2007-06-08
    标题:Inhibitor of biosynthesis of plant hormone auxin, chemical plant regulator comprising the inhibitor as active ingredient, herbicidal agent, and use thereof
    发明人:SHIMADA YUKIHISA; GODA HIDEKI; TACHIKAWA TOMOE; ISHII TAKAHIRO; SOENO KAZUO; FUJIOKA SHOZO; ASAMI TADAO
    权利人:RIKEN; SHIMADA YUKIHISA; GODA HIDEKI; TACHIKAWA TOMOE; ISHII TAKAHIRO; SOENO KAZUO; FUJIOKA SHOZO; ASAMI TADAO
    摘要:The first object is to provide an inhibitor of the synthesis of endogenous auxin. The second object is to provide a plant growth inhibitor or a herbicidal agent utilizing the auxin biosynthesis inhibitor. Thus, disclosed are: a method for screening a candidate for an auxin biosynthesis inhibitor capable of inhibiting the expression of an auxin-inducible gene, by adding each of candidate compounds for the auxin inhibitor to a plant; a method for selecting a compound capable of actually inhibiting the auxin synthesis in a plant, by adding each of candidate compounds to the plant, disrupting the plant and then measuring the amount of endogenous auxin; and a method for selecting a compound capable of inhibiting the production of indolpyruvic acid in the presence of a tryptophan deaminase and tryptophan which are prepared in advance. More specifically disclosed are: an auxin biosynthesis inhibitor comprising AVG, AOA, AOIBA, L-AOPP or an analogue thereof; and a plant growth regulator or a herbicidal agent comprising the compound as an active ingredient.

    专利号:US-9416113-B2
    优先权日:2011-02-10
    标 题:Formation of N-protected bis-3,6-(4-aminoalkyl)-2,5,diketopiperazine
    发明人:FREEMAN JOHN J; STAMPER ADRIENNE; HEITMANN MELISSA
    权利人:MANNKIND CORP; MANNKIND CORP
    摘要:The disclosed embodiments detail improved methods for the synthesis of diketopiperazines from amino acids. In particular improved methods for the cyclocondensation and purification of N-protected 3,6-(aminoalkyl)-2,5-diketopiperazines from N-protected amino acids. Disclosed embodiments describe methods for the synthesis of 3,6-bis-[N-protected aminoalkyl]-2,5-diketopiperazine comprising heating a mixture of an amino acid in the presence of a catalyst in an organic solvent. The catalyst is selected from the group comprising sulfuric acid, phosphoric acid, p-toluenesulfonic acid, 1-propylphosphonic acid cyclic anhydride, tributyl phosphate, phenyl phosphonic acid and phosphorous pentoxide among others. The solvent is selected from the group comprising: dimethylacetamide, N-methyl-2-pyrrolidone, diglyme, ethyl glyme, proglyme, ethyldiglyme, m-cresol, p-cresol, o-cresol, xylenes, ethylene glycol and phenol among others.

    专利号:US-2015099864-A1
    优先权日:2013-10-08
    标题:Preparation of organophosphate peptide adducts
    发明人:BREWER BOBBY N; LUCAS ERIC A; BURKITT NATHAN T
    权利人:BATTELLE MEMORIAL INSTITUTE
    摘要:Disclosed are methods for the synthesis of organophosphorus-adducted peptides. Such peptides may be useful as biomarkers of organophosphate exposure, or for the synthesis of antibodies. Also disclosed are peptide adducts including peptide adducts of tabun, and aged adducts.
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    合成参考文献


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    参考文献:10.1023/a:1014409929875
    摘要:Kononova SV, Nesmeyanova MA. Phosphonates and their degradation by microorganisms. Biochemistry (Mosc). 2002 Feb;67(2):184–95. doi: 10.1023/a:1014409929875.
    参考文献:10.1021/ac035072y
    摘要:Zhou Y, Yu B, Shiu E, Levon K. Potentiometric sensing of chemical warfare agents: surface imprinted polymer integrated with an indium tin oxide electrode. Anal Chem. 2004 May 15;76(10):2689–93. doi: 10.1021/ac035072y.
    参考文献:10.1007/s007750050336
    摘要:Da Costa CP, Sigel H. Stabilities of complexes formed between lead(II) and simple phosphonate or phosphate monoester ligands including some pyrimidine-nucleoside 5′-monophosphates (CMP2–, UMP2–, dTMP2–). JBIC Journal of Biological Inorganic Chemistry. 1999 Aug;4(4):508–14. doi: 10.1007/s007750050336.
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