CAS: 66332-96-5; Flutolanil

该化合物是一种化学化合物,主要用作农业应用中的杀真菌剂,属于类类,其特点是能够抑制真菌生长,使其有效防治各种植物病原体,该化合物通常用于作物,以保护作物免受疾病影响,从而提高产量和质量;氟虫菌对人类和非目标生物的毒性特征相对较低,因此在综合虫害管理战略中是一种首选;其行动方式涉及干扰真菌细胞基本成分的合成,导致菌类发育受抑制;该物质在正常环境条件下一般稳定,但其持久性取决于土壤类型和微生物活动等因素;此外,氟虫素需接受监管评估,以确保其在农业实践中的安全使用,使用者必须遵守应用准则,以尽量减少环境影响.

结构式图片

MSDS等安全信息

欧盟法规

[欧盟农药活性物质

上下游产品

CAS号41406-00-2 3-异丙氧基苯胺 | CAS号312-94-7 2-三氟甲基苯甲酰氯 | CAS号360-64-5 2-(三氟甲基)苯甲酰胺 | CAS号134314-54-8 N-ethoxycarbony... | CAS号433-97-6 邻三氟甲基苯甲酸 | CAS号69392-32-1 N-(3-hydroxyphe... | CAS号134314-55-9 2'-amino-4'-iso...

合成工艺路线路线简述

  • 合成目标产物 Flutolanil 主要起始原料 3-Isopropoxyaniline And 2-(Trifluoromethyl)Benzoyl Chloride
  • (文献来源)合成步骤主要原料 3-Isopropoxyaniline 和 2-(Trifluoromethyl)Benzoyl Chloride
📜3-氨基苯异丙醚,2-三氟甲基苯甲酰氯置于三乙胺盐酸盐,三乙胺体系中,用 四氢呋喃,(2S)-N-Methyl-1-Phenylpropan-2-Amine Hydrate 作为反应溶剂,以91%的收率获得产物氟酰胺
参考文献:Novel Benzoic Anilide Derivative And Fungicide Containing Same
标题:Novel Benzoic Anilide Derivative And Fungicide Containing Same
摘要:由o-三氟甲基苯甲酸和m-异丙氧基苯胺反应形成的o-三氟甲基苯甲酰m'-异丙氧基苯胺,在控制农业和园艺植物病害方面非常有效.

海关参考信息

专利信息


专利号:US-2008287649-A1
优先权日:2006-12-29
标 题 :Methods for the synthesis of cyclic peptides
发明人:CHEN LIN; HAN YEUN-KWEI; ROBERTS CHRISTOPHER R
权利人:CHEN LIN; HAN YEUN-KWEI; ROBERTS CHRISTOPHER R
摘要:Methods for the synthesis of cyclic peptides are provided, as well as novel dipeptide compounds. The methods include the solid phase synthesis of a dipeptide, which is the coupled to a second peptide in a solid phase reaction. The peptide is then cyclized following the coupling reaction. The methods and dipeptides are particularly useful for the synthesis of MC-4 receptor agonist peptides.

专利号:US-2006264608-A1
优先权日:2001-08-03
标题 :Bi-directional synthesis of oligoguanidine transport agents
发明人:WENDER PAUL A; VANDEUSEN CHRISTOPHER L; PATTABIRAMAN KANAKA; PELKEY ERIN T; JESSOP THEODORE C
权利人:WENDER PAUL A; VANDEUSEN CHRISTOPHER L; PATTABIRAMAN KANAKA; PELKEY ERIN T; JESSOP THEODORE C
摘要:Synthesis routes that can be adapted to large scale synthesis of oligoguanidine compounds such as oligoarginine compounds are described which use a perguanidinylation step to convert a group of ω-amino groups to the corresponding guanidinyl groups. These compounds find utility as transport agents. Modified oligoguanidine compounds are also described.

专利号:US-7067698-B2
优先权日:2001-08-03
标 题 :Bi-directional synthesis of oligoguanidine transport agents
发明人:WENDER PAUL A; VANDEUSEN CHRISTOPHER L; PATTABIRAMAN KANAKA; PELKEY ERIN T; JESSOP THEODORE C
权利人:UNIV LELAND STANFORD JUNIOR
摘要:Synthesis routes that can be adapted to large scale synthesis of oligoguanidine compounds such as oligoarginine compounds are described which use a perguanidinylation step to convert a group of ω-amino groups to the corresponding guanidinyl groups. These compounds find utility as transport agents. Modified oligoguanidine compounds are also described.

专利号:US-2015018579-A1
优先权日:2012-02-22
标题:Synthesis of high purity dmt-c3-disulfide phosphoramidite
发明人:SRIVASTAVA SURESH C; THATIKONDA SANTHOSH K; SHUKLA PRAVEEN; SRIVASTAV SANT KUMAR
权利人:SRIVASTAVA SURESH C; THATIKONDA SANTHOSH K; SHUKLA PRAVEEN; SRIVASTAV SANT KUMAR
摘要:The 5′ and 3′-thiol modified oligonucleotides are attractive tools with a vast number of potential applications in the field of nucleic acid chemistry. There is a strong interest in developing new disulfide compounds or to optimize synthesis of existing disulfide modifiers, which are efficient in generating the 3′- or 5′-end reactive thiol group. Various synthetic protocols have been employed to synthesize pure 3-((3-(bis(4-dimethoxytrityl)propyl)di-sulfanyl)propyl 2-cyanoethyl diisopropylphosphoramidite (compound 2) starting from 3-(dimethoxytrityl)propyl)disulfanyl)pro-pan-1-ol, (compound 1). Herein, we describe an efficient, reproducible synthetic and purification protocol for target compound 2 from the compound 1. It is noteworthy that our reaction conditions were reproducible even at multi-gram scale (27 g) with a purity level as achieved in a small scale.

专利号:US-2005069928-A1
优先权日:2003-08-04
标 题 :Methods for synthesis of defined polynucleotides
发明人:NELSON JEFFREY S; MULLIGAN JOHN T; TABONE JOHN C
权利人:BLUE HERON BIOTECHNOLOGY INC
摘要:Disclosed is a significantly improved synthetic method of producing a set of mutagenized progeny polynucleotides which contain at least one substituted codon encoding for each of the 20 naturally encoded amino acids or any selected subset thereof. This in turn, similarly provides a method for producing from a parental template polypeptide, a set of mutagenized progeny polypeptides in which all 20 naturally encoded amino acids is represented at each original amino acid position or any selected subset thereof. The methods described herein enable the synthesis of defined, complex mixtures of oligonucleotides, in instances where the incorporation of degenerate bases is impractical. These oligonucleotide mixtures are useful for a variety of applications such as recombination methods, site-saturation mutagenesis, or the like.

专利号:US-9879043-B1
优先权日:2013-06-06
标 题:Synthesis of non-natural cofactor analogs of S-adenosyl-L-methionine using methionine adenosyltransferase
发明人:THORSON JON; HUBER TYLER; ZHANG JIANJUN; Singh Shanteri
权利人:UNIV KENTUCKY RES FOUND
摘要:The present disclosure relates to the synthesis of non-natural analogs of S-adenosyl-L-methionine (SAM) and/or of Se-adenosyl-L-methionine (SeAM) by reacting a methionine analog and adenosine triphosphate (ATP) in the presence of at least one methionine adenosyltransferase (MAT), and to use thereof with downstream SAM and/or SeAM utilizing enzymes. The non-natural analogs of SAM and/or SeAM have the general formula: n nwhere X is S or Se, and R 1 is an alkyl group.

供应商参考报价(招募中)

品牌试剂参考报价(招募中)

📌 第三方产品分析报告

✅ COA系统入驻 | 共享模式

主要参考文献


1: Guarda PM, Pontes AMS, Domiciano RS, Gualberto LDS, Mendes DB, Guarda EA, da Silva JEC. Assessment of Ecological Risk and Environmental Behavior of Pesticides in Environmental Compartments of the Formoso River in Tocantins, Brazil. Arch Environ Contam Toxicol. 2020 Nov;79(4):524-536. doi: 10.1007/s00244-020-00770-7. Epub 2020 Nov 4.
238:118444. doi: 10.1016/j.saa.2020.118444. Epub 2020 May 6.
266:110565. doi: 10.1016/j.jenvman.2020.110565. Epub 2020 Apr 17.

合成参考文献


摘要:Nippon Noyaku Gakkaishi. Journal of the Pesticide Science Society of Japan., 13(153), 1988
摘要:Krieger R, ed; Handbook of Pesticide Toxicology. Volume 2, 2nd ed. San Diego, CA: Academic Press, p. 1197 (2001)
摘要:Sigma-Aldrich; Safety Data Sheet for Flutolanil. Product Number: N12004, Version 5.0 (Revision Date 06/09/2014). Available from, as of February 13, 2017:
摘要:Muller F et al; Fungicides, Agricultural, 2. Individual Fungicides. Ullmann's Encyclopedia of Industrial Chemistry. 7th ed. (1999-2017). New York, NY: John Wiley & Sons. Online Posting Date: 14 Oct 2011
摘要:WHO/FAO; Joint Meeting on Pesticide Residues; Pesticide Residues in Food - 2002, Toxicological Evaluations p.94 (2002). Available from, as of February 15, 2017: https://apps.who.int/pesticide-residues-jmpr-database
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