CAS: 34743-88-9; 2-(4-Bromophenoxy)Ethanol

该化合物是一种多用途有机化合物,其特点是溴苯氧化合物组,该化合物具有更大的稳定性和溶解性,适合化学工业的各种应用,其独特结构促进其在有机合成中的使用,作为生产药品和农用化学品的一个功能中间体.

结构式图片

欧盟法规

ECHA物质C&L通报REACH预注册

上下游产品

4-bromo-phenol 2-chloro-ethanol sodium 4-bromophenoxide 2-Phenoxyethanol 2,2-dichloro-propionic acid-[2-(4-bromo-phenoxy)-ethyl ester] 5-bromo-2,3-dihydrobenzo[b]furan trimethylsilyl 2-(4-bromophenoxy)ethyl ether 1-bromo-4-(2-chloroethoxy)benzene

合成工艺路线路线简述

    2-溴乙醇置于sodium Hydroxide体系中,用 乙醇 用作溶剂,化学反应 0.5H,以50%的收率获得2-(4-溴苯氧基)乙醇
    参考文献:Wo2006/79988
    标题:Wo2006/79988

    海关参考信息

    专利信息


    专利号:US-2004053999-A1
    优先权日:1997-09-17
    标题 :Novel compounds and methods for synthesis and therapy
    发明人:BISCHOFBERGER NORBERT W; DAHL TERRENCE C; HITCHCOCK MICHAEL J M; KIM CHOUNG U; LEW WILLARD; LIU HONGTAO; MILLS ROGER G; WILLIAMS MATTHEW A
    摘要:Novel compounds are described. The compounds generally comprise an acidic group, a basic group, a substituted amino or N-acyl and a group having an optionally hydroxylated alkane moiety. Pharmaceutical compositions comprising the inhibitors of the invention are also described. Methods of inhibiting neuraminidase in samples suspected of containing neuraminidase are also described. Antigenic materials, polymers, antibodies, conjugates of the compounds of the invention with labels, and assay methods for detecting neuraminidase activity are also described.

    专利号:US-6225341-B1
    优先权日:1995-02-27
    标 题:Compounds and methods for synthesis and therapy
    发明人:BISCHOFBERGER NORBERT W; KIM CHOUNG U; LEW WILLARD; LIU HONGTAO; WILLIAMS MATTHEW A
    权利人:GILEAD SCIENCES INC
    摘要:Novel compounds are described. The compounds generally comprise an acidic group, a basic group, a substituted amino or N-acyl and a group having an optionally hydroxylated alkane moiety. Pharmaceutical compositions comprising the inhibitors of the invention are also described. Methods of inhibiting neuraminidase in samples suspected of containing neuraminidase are also described. Antigenic materials, polymers, antibodies, conjugates of the compounds of the invention with labels, and assay methods for detecting neuraminidase activity are also described.

    专利号:US-4359424-A
    优先权日:1980-07-07
    标题:Substituted phenoxyethoxytetrahydropyran
    发明人:HENRICK CLIVE A; STAAL GERARDUS B
    权利人:ZOECON CORP
    摘要:The compound, cyclopropylmethyl 4-(2-cyclopropylcarbonyloxyethoxy)benzoate, novel intermediates therefor, synthesis thereof, and the use of said compound for the control of pests.

    专利号:US-4304924-A
    优先权日:1980-07-07
    标题:Cyclopropylmethyl benzoates
    发明人:HENRICK OLIVE A; STAAL GERARDUS B
    权利人:ZOECON CORP
    摘要:The compound, cyclopropylmethyl 4-(2-cyclopropylcarbonyloxyethoxy)benzoate, novel intermediates therefor, synthesis thereof, and the use of said compound for the control of pests.
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    合成参考文献


    参考文献:10.1055/s-0040-1706296
    摘要:El-Faham A, Albericio F, Manne SR, de la Torre BG. OxymaPure Coupling Reagents: Beyond Solid-Phase Peptide Synthesis. Synthesis. 2020 Sep 30;52(21):3189–210. doi: 10.1055/s-0040-1706296.
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