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485841-52-9 623586-02-7 170033-47-3欧盟法规
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3,4-dimethyl-piperazine-1-carboxylic acid ethyl ester 3-methylpiperazin-2-one 3-methylpiperazine-1-carboxylic acid ethyl ester 4-benzyl-3-methyl-piperazine-1-carboxylic acid ethyl ester ethyl 4-(3,4-dimethylpiperazin-1-yl)benzoate N-[5-[2-(3,5-dimethoxyphenyl)ethyl]-2H-pyrazol-3-yl]-5-(3,4-dimethylpiperazin-1-yl)pyrazine-2-carboxamide N-[5-[(3,5-dimethoxyphenyl)methoxy]-2H-pyrazol-3-yl]-5-(3,4-dimethylpiperazin-1-yl)pyrazine-2-carboxamide 8-(4-((3,4-dimethylpiperazin-1-yl)methyl)phenyl)-9-(4-fluorophenyl)-8,9-dihydro-2H-pyrido[4,3,2-de]phthalazin-3(7H)-one合成工艺路线路线简述
- 合成目标产物 1,2-Dimethyl-Piperazine 主要起始原料 4-N-Boc-2-Methyl-Piperazine
- (文献来源)合成步骤主要原料 4-N-Boc-2-Methyl-Piperazine
专利信息
专利号:EP-1575929-B1
优先权日:2002-12-19
标 题 :The method for production of semi-finished products useful in synthesis of paclitaxel
发明人:KOLESINSKA BEATA; KAMINSKI J ZBIGNIEW; KAMINSKA E JANINA
权利人:AGROPHARM S A
摘要:The method for production of the semi-finished products useful in synthesis of Paclitaxel with the generalized formula (2), characterized in that phenyl isoserine derivatives, or mixtures of their epimerides with various configurations on the carbon 2' or their salts, are treated with triazine type condensing agent, possible in the presence of tertiary amine, in medium of anhydrous organic solvent, and the triazine esters produced are treated with Baccatin III, in medium of anhydrous organic solvent, possible in the presence of a catalyst.
专利号:EP-0909792-B1
优先权日:1997-10-15
标 题:Storage-stable composition for the synthesis of polyurethanes
发明人:BAUMANN EDWIN; HAEBERLE KARL DR; HORN PETER DR; TREULING ULRICH DR; SCHWAEBISCH HANS
权利人:BASF AG
摘要:Polyurethane synthesis composition using a polymeric emulsifier having a backbone consisting of a copolymer of 4-12C unsaturated dicarboxylic acid or anhydrides and 2-40C olefins, with polyoxyalkylene side chains derived from 2-20C oxiranes. A polyurethane (PU) synthesis composition containing, as emulsifier, a polymer (T) with (at least) a copolymer backbone (TR) derived from 4-12 carbon(C) unsaturated dicarboxylic acid(s) and/or their anhydrides (TR1) and 2-40 C olefin(s) (TR2), and having polyalkylene oxide side chain (TP) derived from 2-20 C oxirane(s) (TP1), together with at least two compounds (a) comprising at least two reactive hydrogen atoms, at least one of which is insoluble. Independent claims are also included for: (a) a process for the production of synthesis composition by contacting the components in presence of a polymer; (b) a PU synthesis composition obtained; (c) a polyurethane obtained by bringing the synthesis composition into contact with a polyisocyanate; and (d) moldings, fibers, coatings, paint, sheets and a foam made from the PU compositions.
专利号:WO-2018229798-A1
优先权日:2017-06-13
标题 :Process for the preparation of bictegravir and intermediate thereof
发明人:PHULL MANJINDER SINGH; RAO DHARMARAJ RAMACHANDRA; BIRARI DILIP RAMDAS
权利人:CIPLA LTD
摘要:The present invention provides processes and intermediates for the synthesis of bictegravir and its pharmaceutical salt.
专利号:US-2017341036-A1
优先权日:2014-11-04
标题 :Improved method for synthesis of polyamide composite membranes
发明人:MARIËN Hanne; VANKELECOM IVO; HERMANS SANNE
权利人:UNIV LEUVEN KATH
摘要:The present invention provides a method for the preparation of thin film composite (TFC) membranes, preferably solvent resistant TFC membranes, by interracial polymerization (IFP), more in particular solvent resistant TFC membranes wherein a thin PA-layer is deposited on a porous support membrane. Said method comprises the replacement of the aqueous and/or the organic solvent in the IFP method by an ionic liquid (IL) as solvent for the monomers which form said TFC membranes, to alter the top layer morphology, thickness and crosslinking degree.
专利号:WO-2024104923-A1
优先权日:2022-11-16
标 题 :Manganese- and iron-containing catalysts comprising an imine ligand for the synthesis of polyurethanes
发明人:SCHAUB THOMAS; JOOST MAXIMILIAN; SALA OLIVER; RUDDIGKEIT MIRIAM; POELTL JOERG; BOKERN STEFAN; KAMM MARINA; HASHMI A STEPHEN K; OCANSEY EDWARD
权利人:BASF SE
摘要:The present invention relates to a process for the production of a polyurethane comprising the application of a manganese- and iron-containing catalysts wherein the catalyst comprises at least on imine ligand, which is defined by the general formula (I). The catalysts comprise a salicylaldehyde based imine according to the general formula (II) as an imine ligand. The present invention is further directed to a polyol component comprising a catalyst according to the invention, and a polyurethane produced according to such a process.
专利号:US-8334386-B2
优先权日:2007-07-03
标题:Aqueous synthesis of perylene pigments
发明人:LOEBEL JOHANNES; STOHR ANDREAS
权利人:LOEBEL JOHANNES; STOHR ANDREAS; BASF SE
摘要:A process for preparing perylene pigments of the general formula (Ia) or (Ib) n nor mixtures thereof, by reacting perylenetetracarboxylic acids or functional derivatives thereof with aromatic diamines, where R 1 , R 2 may be the same or different and may each independently be phenylene, naphthylene or pyridylene, where R 1 , R 2 may each be mono- or polysubstituted by C 1 -C 22 -alkyl, C 3 -C 22 -alkenyl, C 1 -C 22 -alkoxy, hydroxyl and/or halogen, X 1 , X 2 , X 3 , X 4 , X 5 , X 6 , X 7 , X 8 may be the same or different and may each independently be hydrogen or halogen, wherein the reaction is performed in the presence of a secondary or tertiary amine in an aqueous reaction medium.