CAS: 1215011-08-7; 2,6-Dichloro-N-(3-Isobutyl-1,5-Dimethyl-1H-Pyrazol-4-yl)-4-(2-(Piperazin-1-yl)Pyridin-4-yl)Benzenesulfonamide
- 英文名称2,6-Dichloro-N-(3-Isobutyl-1,5-Dimethyl-1H-Pyrazol-4-yl)-4-(2-(Piperazin-1-yl)Pyridin-4-yl)Benzenesulfonamide
- 中文名称2,6-二氯-N-(3-异丁基-1,5-二甲基-1H-吡唑-4-基)-4-(2-(哌嗪-1-基)吡啶-4-基)苯磺酰胺
- IUPAC名称2,6-dichloro-N-(3-isobutyl-1,5-dimethyl-1H-pyrazol-4-yl)-4-(2-(piperazin-1-yl)pyridin-4-yl)benzenesulfonamide
- 其它别名Benzenesulfonamide, 2,6-Dichloro-N-[1,5-Dimethyl-3-(2-Methylpropyl)-1H-Pyrazol-4-Yl]-4-[2-(1-Piperazinyl)-4-Pyridinyl]-; 2,6-Dichloro-N-(3-Isobutyl-1,5-Dimethyl-1H-Pyrazol-4-yl)-4-(2-(Piperazin-1-yl)Pyridin-4-yl)Benzenesulfonamide; 2,6-Dichloro-4-(2-Piperazin-1-Ylpyridin-4-yl)-N- (1,5-Dimethyl,3-Isobutyl-1H-Pyrazol-4-yl)Benzenesulfonamide
- CAS编号1215011-08-7
- FDA UNII编号:5HY8BYC3Q6
- 分子式:C24H30Cl2N6O2S分子量:537.52
- 产品CID: 295944
- 同类组份化合物CAS1215011-08-7 (free base)DDD86481 Tosylate
- 产品分类Chemistry → Heterocyclic Building Blocks → Aromatic Heterocycles | Pyrazoles | Piperazines
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- 2903919090-氯苯
2921211000-乙二胺
2933310010-吡啶
2939800000-其他生物碱 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
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主要参考文献
1: Liu N, Tu J, Dong G, Wang Y, Sheng C. Emerging New Targets for the Treatment of Resistant Fungal Infections. J Med Chem. 2018 Jan 16. doi: 10.1021/acs.jmedchem.7b01413. [Epub ahead of print] A.; Raimi, O. G.; Blair, D. E.; Harrison, J. R.; Lockhart, D. E.; Torrie, L. S.; Ruda, G. F.; Wyatt, P. G.; Gilbert, I. H.; van Aalten, D. M. N-myristoyltransferase is a cell wall target in aspergillus fumigatus. ACS Chem. Biol. 2015, 10, 1425−1434.
合成参考文献
参考文献:10.1021/acs.jmedchem.6b01817
摘要:Buuh ZY, Lyu Z, Wang RE. Interrogating the Roles of Post-Translational Modifications of Non-Histone Proteins. J Med Chem. 2018 Apr 26;61(8):3239–52. doi: 10.1021/acs.jmedchem.6b01817.
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