CAS: 1137-41-3; (4-Aminophenyl)(Phenyl)Methanone

相似化合物

611-98-3 2835-78-1 611-79-0

上下游产品

N-phenylphthalimide benzoyl chloride benzophenone 4-nitrobenzophenone ethyl (4-benzoylphenyl)carbamate N-(4-benzoylphenyl)acetamide 1-(4-Aminophenyl)-1-phenylethanol 3-nitro-4,4''-imino-di-benzophenone

N-苯甲酰替苯胺置于甲烷磺酸,四磷十氧化物,Sodium Hydroxide体系中,用 水 用作溶剂,以46%的收率获得4-氨基二苯甲酮
参考文献:甲磺酸中五氧化二磷存在下苯胺的 Fries 重排
标题:甲磺酸中五氧化二磷存在下苯胺的 Fries 重排
摘要:通过与各种路易斯酸(如 Zncl2,Sncl4,Ticl4,Thcl4 和 Bicl3)的光解或热解(高于 200-350oc).乙酰苯胺在沸石催化剂上的 Fries 重排也有报道,在 280oc 下转化率为 50%.19 最近报道了使用强碱通过阴离子重排进行的苯胺 Fries 型重排.20 甲磺酸是一种布朗斯台德酸用作缩合或重排反应的催化剂和溶剂.21-23 它在酚酸酯的 Fries 重排中用作催化剂是已知的.24-26 添加 P2O5 增加了有机化合物在已广泛使用的甲磺酸中的溶解度27 作为我们探索有机转化方法的努力的一部分,28-45 我们描述了在甲磺酸中 Pocl3 存在下合成酰芳基甲磺酸酯的酚酯 Fries 重排的新方法. 46 在此,我们报告了在 P2O5 混合物存在下苯胺的 Fries 重排甲磺酸 (1:7) 作为选择性合成对氨基芳基酮的有效试剂.苯甲酰苯胺 (1A) 的 Fries
Doi:10.1080/00304940902956093

专利信息

专利号:US-12251674-B2
优先权日:2012-11-14
标 题:Substrates, systems, and methods for array synthesis and biomolecular analysis
发明人：RAJASEKARAN JOHN J; JAYARAMAN VASANTH; WANG TIANHAO; BEI KANG; KRISHNAMURTHY HARI KRISHNAN; VEDANTHAM PUNITHA
权利人:VIBRANT HOLDINGS LLC
摘要:Disclosed herein are formulations, substrates, and arrays. In certain embodiments, substrates and arrays comprise a porous layer for synthesis and attachment of polymers or biomolecules. Also disclosed herein are methods for manufacturing and using the formulations, substrates, and arrays, including porous arrays. Also disclosed herein are formulations and methods for one-step coupling, e.g., for synthesis of peptides in an N→C orientation. In some embodiments, disclosed herein are formulations and methods for high efficiency coupling of biomolecules to a substrate.

专利号:US-7514465-B2
优先权日:2004-11-16
标题 :Synthesis of N2-(substituted arylmethyl)-3-(substituted phenyl)indazoles as novel anti-angiogenic agents
发明人：KUO SHENG-CHU; HUANG LI-JIAU; LEE FANG-YU; TENG CHE-MING; SHIH MEI-LING; CHEN HUA-SIN
权利人:YUNG SHIN PHARM IND CO LTD
摘要:Novel compounds of 2-(substituted arylmethyl)-3-(substituted phenyl)-2H-indazoles and 1-(substituted arylmethyl)-3-(substituted phenyl)-1H-indazoles are synthesized, and useful as anti-angiogenic agents.

专利号:US-3872218-A
优先权日:1972-03-06
标题 :Synthesis of alkali metal tetracarbonylferrates
发明人：COLLMAN JAMES P; WINTER STANLEY R
权利人:UNIV LELAND STANFORD JUNIOR
摘要:Production of alkali metal tetracarbonylferrate by reaction of alkali metal with an iron carbonyl, preferably iron pentacarbonyl (Fe(CO)5), in a suitable solvent and in the presence of an electron carrier. Alkali metal may be in solid phase or liquid phase.

专利号:US-6849650-B2
优先权日:1998-02-27
标 题:Heterocyclic compounds, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds
发明人：THORSETT EUGENE D; PORTER WARREN J; NISSEN JEFFREY S; LATIMER LEE H; AUDIA JAMES E; DROSTE JAMES
权利人:ATHENA NEUROSCIENCES INC; LILLY CO ELI
摘要:Disclosed are compounds which inhibit β-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions comprising a compound which inhibits β-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.

专利号:US-6399628-B1
优先权日:1996-11-22
标 题 :N-(aryl/heteroaryl) amino acid esters, pharmaceutical compositions comprising same, and methods for inhibiting alpha- amyloid peptide release and/or its synthesis by use of such compounds
发明人：AUDIA JAMES E; FOLMER BEVERLY K; JOHN VARGHESE; LATIMER LEE H; NISSEN JEFFREY S; REEL JON K; THORSETT EUGENE D; WHITESITT CELIA A
权利人:ATHENA NEUROSCIENCES INC; LILLY CO ELI
摘要:Disclosed are compounds which inhibit β-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions comprising a compound which inhibits β-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.

专利号:EP-0951466-B1
优先权日:1996-12-23
标题:Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting beta-amyloid peptide release and/or its synthesis by use of such compounds
发明人：WU JING; TUNG JAY S; THORSETT EUGENE D; PLEISS MICHAEL A; NISSEN JEFFREY S; NEITZ JEFFREY; LATIMER LEE H; JOHN VARGHESE; FREEDMAN STEPHEN; BRITTON THOMAS C; AUDIA JAMES E; REEL JON K; MABRY THOMAS E; DRESSMAN BRUCE A; CWI CYNTHIA L; DROSTE JAMES J; HENRY STEVEN S; MCDANIEL STACEY L; SCOTT WILLIAM L; STUCKY RUSSELL D
权利人:ELAN PHARM INC; LILLY CO ELI
摘要:Disclosed are compounds for Formula (I) wherein the substituents are as defined in the claims which inhibit β-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions comprising a compound which inhibits β-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.