CAS: 910-86-1; Isoxyl
该化合物是一种专门的有机化合物,由硫尿素功能组组成,以4-(3-甲基丁氧)苯基质替代.这种结构具有独特的反应性和溶性特性,在有机合成,协调化学和材料科学等应用中具有价值.3-甲基丁氧组的存在会增加脂性,改善与非极质基体的兼容性.它的硫尿核心能够产生强大的氢-苯相互作用,有助于分子识别或催化.该化合物在中度条件下的稳定性和量身定制的功能化潜力使它成为先进的化学工艺的多功能中间体.由于对湿度或氧化可能具有敏感性,因此建议谨慎处理.
- 英文名称Isoxyl
- 中文名称戊氧苯硫脲
- IUPAC名称1,3-bis(4-(isopentyloxy)phenyl)thiourea
- 其它别名N,N'-Bis[4-(3-Methylbutoxy)Phenyl]Thiourea; Amixyl; Disoxyl; Thiourea, N,N'-Bis(4-(3-Methylbutoxy)Phenyl)-; Isoxyl
- CAS编号910-86-1
- MFCD编号:MFCD00866807
- EINECS号:213-006-5
- FDA UNII编号:43M23X81Y2
- 分子式:C23H32N2O2S分子量:400.59
- 产品CID: 1945604
- 产品分类化学试剂 → 有机试剂 → 硫脲
物理性质
MSDS等安全信息
上下游产品
CAS号463-71-8 硫光气 | CAS号5198-05-0 对-氨基苯酚异-戊醚 | CAS号75-15-0 二硫化碳 | CAS号100-02-7 对硝基苯酚 | CAS号107-82-4 溴代异戊烷 | CAS号5198-05-0 对-氨基苯酚异-戊醚合成工艺路线路线简述
- 7244-79-3 = 910-86-1
反应条件:1.1 Reagents: Hydrogen Catalysts: Palladium Solvents: Ethanol; 3 H,Rt1.2 Catalysts: 4-(Dimethylamino)Pyridine; 18 H,Reflux
标题:Radical Anion Promoted Chemoselective Cleavage Of Csp2-S Bond Enables Formal Cross-Coupling Of Aryl Methyl Sulfones With Alcohols
作者:Bai,Jixiang; Wang,Tianxin; Dai,Botao; Liu,Qingchao; Yu,Peiyuan; Et Al
参考文献:Organic Letters 日期:2021 卷标:23(15) 页码:5761-5765]
5198-05-0 = 910-86-1
反应条件:1.1 Reagents: Triethylamine Solvents: Dichloromethane; 15 Min,Rt1.2 Solvents: Dichloromethane; Rt; Overnight,Rt
标题:The Structure-Activity Relationship Of Urea Derivatives As Anti-Tuberculosis Agents
作者:Brown,Joshua R.; North,Elton J.; Hurdle,Julian G.; Morisseau,Christophe; Scarborough,Jerrod S.; Et Al
参考文献:Bioorganic & Medicinal Chemistry 日期:2011 卷标:19(18) 页码:5585-5595]
5198-05-0 = 910-86-1
反应条件:1.1 Reagents: Potassium Ethylxanthate Solvents: Ethanol; 6 H,Rt
标题:Preparation And Properties Of New Antitubercular Thioureas And Thiosemicarbazides
作者:Hearn,Michael; Chen,Michaeline; Cynamon,Michael; Wang'Ondu,Ruth; Webster,Eleanor
参考文献:Journal Of Sulfur Chemistry 日期:2006 卷标:27(2) 页码:149-164]
103-90-2 = 910-86-1
反应条件:1.1 -1.2 Acidified,Reflux1.3 Catalysts: Sulfur Solvents: Ethanol
标题:Symmetrical And Unsymmetrical Analogues Of Isoxyl; Active Agents Against Mycobacterium Tuberculosis
作者:Bhowruth,Veemal; Brown,Alistair K.; Reynolds,Robert C.; Coxon,Geoffrey D.; Mackay,Simon P.; Et Al
参考文献:Bioorganic & Medicinal Chemistry Letters 日期:2006 卷标:16(18) 页码:4743-4747]
81928-78-1 = 910-86-1
反应条件:1.1 Reagents: Hydrochloric Acid Solvents: Water1.2 Catalysts: 4-(Dimethylamino)Pyridine
标题:Scalable And Phosphine-Free Conversion Of Alcohols To Carbon-Heteroatom Bonds Through Blue-Light Promoted Iodination Reaction
作者:Liu,Bin; Elder,W. Zachary; Miyake,Garret M.
参考文献:Journal Of Organic Chemistry 日期:2020 卷标:85(5) 页码:3717-3727
📜对-氨基苯酚异-戊醚置于五甲基二乙烯三胺,水,乙酸酐,Sulfur,三乙胺,三氯氧磷体系中,用 四氢呋喃 作为反应溶剂,化学反应 2.5H,反应生成 戊氧苯硫脲
参考文献:单质硫水溶液无需色谱法多组分合成硫脲
标题:单质硫水溶液无需色谱法多组分合成硫脲
摘要:异氰化物,胺和元素硫的新型三组分无色谱反应的开发使我们能够在水中直接合成硫脲.考虑到大量的有机和无机碱,我们首先优化了从元素硫制备多硫化物水溶液的方法.使用多硫化物溶液,我们能够省略原本必须进行的色谱法,并通过简单的过滤直接从反应混合物中分离结晶产物,将硫保留在溶液相中.以这种方式合成的各种硫脲证实了我们的方案的合理底物和官能团耐受性.
DOI:10.1002/open.202000250
海关参考信息
- 2905121000-正丙醇
2905130000-正丁醇
2908199090-其他酚的卤化衍生物
2908999090-其他酚的硝化衍生物 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:US-4432817-A
优先权日:1982-03-25
标题 :Propellant containing an azidonitrocarbamate plasticizer
发明人：FRANKEL MILTON B; WITUCKI EDWARD F
权利人:US AIR FORCE
摘要:This invention involves the synthesis of a novel family of azido nitrocarbamates and their utilization as energetic liquid plasticizers for advanced solid propellant compositions. The novel family of plasticizers is represented specifically by the novel compound, 1,3-diazido-2-propyl-N-nitro-N-trinitropropyl carbamate.
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
主要参考文献
1: Meyer A, Nadjar-Fossé G. L'association isoniazide-tiocarlide ou DAT dans le traitement de la tuberculose pulmonaire. Comparaison avec l'association isoniazide-PAS et plus particulièrement le BPAS [Isoniazide-tiocarlide combination or DAT in the treatment of pulmonary tuberculosis. Comparison with isoniazide-PAS combination and especially BPAS]. Rev Tuberc Pneumol (Paris). 1968 Apr-May;32(3):371-80. French. 23(6):729-38. French.
合成参考文献
摘要:Mlczoch F, Wildner F. [Critical remarks on a clinical test of an antitubercular agent. Experiences with thiocarlide during collective work]. Prax Pneumol. 1969 Jan;23(1):1–16.
摘要:Janowiec M. [Antitubercular properties of isoxyl (4,4-di-isoamyl-oxycarbanilid)]. Gruzlica. 1969 May;37(5):417–23.
参考文献:10.1016/j.bmcl.2008.03.033
摘要:Liav A, Angala SK, Brennan PJ, Jackson M. N-d-Aldopentofuranosyl-N′-[p-(isoamyloxy)phenyl]-thiourea derivatives: Potential anti-TB therapeutic agents. Bioorganic & Medicinal Chemistry Letters. 2008 Apr;18(8):2649–51. doi: 10.1016/j.bmcl.2008.03.033.
摘要:Lambelin G, Parmentier R. Study of the toxicity of isoxyl. Research on the pathological effects of isoxyl in the rat undergoing chronic experimentation. Arzneimittelforschung. 1966 Jul;16(7):881–6.
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