CAS: 6236-10-8; (R)-2-Hydroxy-2-Methylsuccinic Acid

上下游产品

CAS号597-44-4 2-hydroxy-2-met... | CAS号93206-60-1 (S)-(-)-3-羟基-3-... | CAS号498-23-7 柠康酸 | CAS号66261-38-9 3-ethoxycarbony... | CAS号65527-85-7 (E)-4-羟基-3-甲基丁-... | CAS号79-41-4 甲基丙烯酸 | CAS号80320-89-4 (4R)-4-[2-(benz... | CAS号81426-68-8 dimethyl (2R)-2...

📜(-)-Isotetradehydrofurospongin-1置于臭氧,Jones Reagent体系中,用 二氯甲烷 作为反应溶剂,以25%的收率获得产物(R)-(-)-柠苹酸
参考文献:海洋c21双呋喃并萜的结构修订和绝对立体化学的分配.
标题:海洋c21双呋喃并萜的结构修订和绝对立体化学的分配.
摘要:C21双呋喃萜(-)-异四氢呋喃核糖核酸-1(6)先前从西澳大利亚海绵状海绵中分离出来,已从在大澳大利亚海域进行科学拖网作业时收集的螺旋藻螺旋藻标本中分离出来.对6的2D NMR分析提示已公开结构5的重新分配,而降解和手性HPLC分析则允许确定绝对立体化学.
DOI:10.1021/np000477O

专利信息

专利号:US-11046978-B2
优先权日:2016-03-16
标 题:Synthesis of isoprenoids and derivatives
发明人：GONZALEZ RAMON; CLOMBURG JAMES M; CHEONG SEOKJUNG
权利人:UNIV RICE WILLIAM M
摘要:This disclosure generally relates to the use of enzyme combinations or recombinant microbes comprising same to make isoprenoid precursors, isoprenoids and derivatives thereof including prenylated aromatic compounds. Novel metabolic pathways exploiting Claisen, aldol, and acyioin condensations are used instead of the natural mevalonate (MVA) pathway or 1-deoxy-d-xylulose 5-phosphate (DXP) pathways for generating isoprenoid precursors such as isopentenyl pyrophosphate (IPP), dimethylallyl pyrophosphate (DMAPP), and geranyl pyrophosphate (GPP). These pathways have the potential for better carbon and or energy efficiency than native pathways. Both decarboxylative and non-carboxylative condensations are utilized, enabling product synthesis from a number of different starting compounds. These condensation reactions serve as a platform for the synthesis of isoprenoid precursors when utilized in combination with a variety of metabolic pathways and enzymes for carbon rearrangement and the addition/removal of functional groups. Isoprenoid alcohols are key intermediary products for the production of isoprenoid precursors in these novel synthetic metabolic pathways.

专利号:US-2004110228-A1
优先权日:2002-04-01
标 题:Combinatorial organic synthesis of unique biologically active compounds
发明人：MCALPINE SHELLI R; TAYLOR RACHEL E; BOLLA MEGAN L; SEGALL ANCA M
摘要:The invention provides a method for making a combinatorial library of cyclic compounds, such as Holliday junction-trapping compounds, comprising the steps of (a) obtaining a plurality of trimers according to the generic structure X 1- X 2- X 3 , wherein X 1 , X 2 and X 3 can be independently any naturally or nonnaturally occurring amino acids or peptidomimetics thereof; (b) optionally coupling a spacer S to the trimer at either end; (c) cyclizing two trimers or trimer-spacer conjugates in a head-to-tail orientation; thereby obtaining a combinatorial library of compounds, wherein the library does not include an unmodifed or naturally occurring Holliday Junction-trapping compounds. The invention additionally provides methods macrocyclic compounds that are synergimycin derivatives.

专利号:US-9481898-B2
优先权日:2010-01-15
标题 :Electro-autotrophic synthesis of higher alcohols
发明人：LIAO JAMES C; CHO KWANG MYUNG
权利人:UNIV CALIFORNIA
摘要:The disclosure provides a process that converts CO 2 to higher alcohols (e.g. isobutanol) using electricity as the energy source. This process stores electricity (e.g. from solar energy, nuclear energy, and the like) in liquid fuels that can be used as high octane number gasoline substitutes. Instead of deriving reducing power from photosynthesis, this process derives reducing power from electrically generated mediators, either H 2 or formate. H 2 can be derived from electrolysis of water. Formate can be generated by electrochemical reduction of CO 2 . After delivering the reducing power in the cell, formate becomes CO 2 and recycles back. Therefore, the biological CO 2 fixation process can occur in the dark.

专利号:US-11225655-B2
优先权日:2010-04-16
标题:Bi-functional complexes and methods for making and using such complexes
发明人：GOULIAEV ALEX HAAHR; FRANCH THOMAS; GODSKESEN MICHAEL ANDERS; JENSEN KIM BIRKEBAEK
权利人:GOULIAEV ALEX HAAHR; FRANCH THOMAS; GODSKESEN MICHAEL ANDERS; JENSEN KIM BIRKEBAEK; NUEVOLUTION AS
摘要:The present invention is directed to a method for the synthesis of a bi-functional complex comprising a molecule part and an identifier oligonucleotide part identifying the molecule part. A part of the synthesis method according to the present invention is preferably conducted in one or more organic solvents when a nascent bi-functional complex comprising an optionally protected tag or oligonucleotide identifier is linked to a solid support, and another part of the synthesis method is preferably conducted under conditions suitable for enzymatic addition of an oligonucleotide tag to a nascent bi-functional complex in solution.

专利号:WO-2017161041-A1
优先权日:2016-03-16
标 题 :Microbial synthesis of isoprenoid precursors, isoprenoids and derivatives including prenylated aromatics compounds

专利号:US-2016024533-A1
优先权日:2010-01-15
标 题 :Electro-autotrophic synthesis of higher alcohols