CAS: 620-02-0; 5-Methyl-2-Furaldehyde

相似化合物

1917-15-3 2527-96-0 3857-25-8

上下游产品

2-methylfuran hydrogen cyanide N,N-dimethyl-formamide N-methyl-N-phenylformamide 5-methyl-2-propionylfuran 2-hydroxymethyl-5-methylfuran 5-(5-methyl-furan-2-ylmethylene)-pyrimidine-2,4,6-trione 2-(5-methyl-2-furyl)-1-nitroethylene

D-甘露糖置于甲酸,Sodium Iodide体系中,用 水,甲苯 作为反应溶剂,以30.5%的收率获得产物5-甲基呋喃醛
参考文献:碘化物介导的转移氢化从 D-果糖直接合成 5-甲基糠醛
标题:碘化物介导的转移氢化从 D-果糖直接合成 5-甲基糠醛
摘要:转移氢化:5-甲基糠醛 (5-Mf) 是一种很有前途的 C 6平台分子,通过碘化物介导的转移氢化直接从生物质衍生的碳水化合物中生产.在优化条件下,30-50% 的 5-Mf 来自低成本糖和淀粉,5-Mf 生产率高达 103 Mmol G Cat-1 H-1.该催化系统简单,坚固,可回收,优于其他生产 5-Mf 的方法.
DOI:10.1002/cssc.202102021

专利信息

专利号:US-11427596-B2
优先权日:2019-07-19
标 题:Metal-free solvent-free synthesis of fused-pyrido heterocycles and biomedical applications
发明人：CHELVAM VENKATESH; DUDHE PREMANSH; KRISHNAN MENA ASHA; SONAWANE AVINASH
权利人:INDIAN INSTITUTE OF TECH INDORE
摘要:Embodiments herein provide fused-pyrido heterocycles such as azaindoles, carboline derivatives, furo[b]pyridines or furo[b]pyridine-isatin hybrids of Formula I.Embodiments also relate to a process for a synthesis of variety of complex pyrido-heterocycles The pyrido-heterocycles can be used for treating cancer (cervix, kidney, lung, breast and epidermal skin) and multi-drug resistant tuberculosis. These heterocycles can also be used as anti-biofilm agents against pathogenic strains, which will minimize the risk of secondary infections.

专利号:US-10266565-B2
优先权日:2011-04-12
标 题 :Peptide mimetic ligands of polo-like kinase 1 polo box domain and methods of use
发明人：BURKE JR TERRENCE R; LIU FA; LEE KYUNG S; PARK JUNG-EUN
权利人:BURKE JR TERRENCE R; LIU FA; LEE KYUNG S; PARK JUNG EUN; THE US SECRETARY DEPARTMENT OF HEALTH & HUMAN SERVICES
摘要:Novel compounds are provided that bind to polo-like kinases through the polo-box domain. In certain embodiments, the novel compounds are PEGylated peptides. The PEGylated peptides in accordance with the invention demonstrate high PBD-binding affinity. In certain embodiments, the PEGylated peptides have also achieved activities in whole cell systems. The invention also provides compounds that bind polo-like kinases through the polo-box domain and possess reduced anionic charge. Further provided are methods of design and/or synthesis of the PEGylated peptides and methods of use thereof. The invention provides methods of use of the compounds and methods of synthesis of the compounds.

专利号:US-2016052902-A1
优先权日:2013-04-25
标 题:Catalytic synthesis of reduced furan derivatives
发明人：SANBORN ALEXANDRA; BINDER THOMAS P
权利人:ARCHER DANIELS MIDLAND CO
摘要:The present invention relates to catalytic synthesis of furan derivatives from alkoxymethylfurfural ethers or acyloxymethylfurfural esters. More particularly, the invention pertains to furan derivatives obtained by use of a multifunctional catalyst system to carry out both hydrogenation of furan starting material and hydrolysis of the reduced furan derivative in a single reaction. The process allows recovering and recycling of alcohol or acid from the reaction product.

专利号:US-9783517-B2
优先权日:2010-08-19
标题 :Method for synthesis of an output including diesters of 5-methyl-2-furoic acid
发明人：CAHANA AVIAD; MARTIN TIM
权利人:CAHANA AVIAD; MARTIN TIM; XF TECH INC
摘要:The present invention describes methods and apparatuses for the synthesis of 5-(chloromethyl)-2-furaldehyde (CMF) from saccharides in pure or crude form, the method comprising: (a) continuously contacting saccharides in pure or crude form, hydrochloric acid, and an organic solvent, by way of a continuous, biphasic-flow reactor assembly at a temperature from about 60 degrees C. to about 200 degrees C. and pressures from about 1 atmosphere to about 20 atmospheres, such that CMF is produced; (b) separating 5-(chloromethyl)-2-furaldehyde by liquid/liquid and solid/liquid phase separation; (c) producing at least five kilograms per day with at least 50% yield. Embodiments of the present invention can produce CMF in a continuous fashion, with high yield and without degradation of CMF to such side products as 5-(hydroxymethyl)furfural (HMF), 2-(2-hydroxyacetyl)furan (HAF) and levulinic acid (LA).

专利号:US-9975866-B2
优先权日:2013-11-21
标 题:Process for synthesis of furan derivative using an acid catalyst and preparation thereof
发明人：LALI ARVIND MALLINATH; PAWAR HITESH SURESH
权利人:DEPARTMENT OF BIOTECH MINISTRY OF SCIENCE AND TECH GOVERNMENT OF INDIA; INSTITUTE OF CHEMICAL TECH; DEPARTMENT OF BIOTECH MINISTRY OF SCIENCE AND TECH GOVERNMENT OF INDIA
摘要:In accordance with the present subject matter, there is provided a process for preparing a furan derivative, the process comprising the steps of contacting a sugar with a monophasic organic solvent to obtain a reaction mixture; and subjecting the reaction mixture to a temperature in the range from 100° C. to 180° C., in presence of an acid catalyst, for a time period in the range of 0.5 min to 4.0 h to obtain at least 70% conversion of the sugar to a single furan derivative, wherein the acid catalyst is selected from the group consisting of homogenous acid catalyst, heterogenous solid acid catalyst, and combinations thereof. There is also provided a process for preparation of a heterogenous solid acid catalyst.

专利号:US-2022356139-A1
优先权日:2019-09-03
标 题:Synthesis of deuterated aldehydes
发明人：WANG WEI
权利人:ARIZONA BOARD OF REGENTS ON BEHALF OF ATHE UNIV OF ARIZONA
摘要:Described are methods for preparing a deuterated aldehyde using N-heterocyclic carbene catalysts in a solvent comprising D 2 O. The methods may be used to convert a wide variety of aldehydes (e.g., aryl, alkyl, or alkenyl aldehydes) to C-1 deuterated aldehydes under mild reaction conditions without functionality manipulation.