CAS: 5663-96-7; Oct-2-Ynoic Acid

相似化合物

111-12-6 10519-20-7 20739-58-6

上下游产品

1-chloro-hept-1-ene chloroformic acid ethyl ester sodioheptyne methylammonium carbonate methyl 2-°Ctynoate ethyl 2-°Ctynoate (Z)-°Ct-2-enoic acid 1-Heptyne

📜(1-Chloro-oct-2-Ynylsulfanyl)-Benzene置于jones Reagent,Sodium Carbonate体系中,用 丙酮 作为反应溶剂,化学反应 25.0H,反应生成 2-辛炔酸
参考文献:从 2-乙酰苯硫醚合成 2-乙酰羧酸,1-亚磺酰基和 1-磺酰基-2-酮
标题:从 2-乙酰苯硫醚合成 2-乙酰羧酸,1-亚磺酰基和 1-磺酰基-2-酮
摘要:摘要 用磺酰氯在 1-位单氯化,然后甲醇分解将 2-炔基苯硫醚转化为 1-甲氧基-2-炔基苯硫醚.用铬酸氧化得到2-炔羧酸.用 Oxone® 和过氧化氢在乙酸中氧化 2-炔属苯硫醚,分别得到相应的亚砜和砜.二乙胺加成到三键产生烯胺,用盐酸水溶液将其水解成相应的 1-亚磺酰基和 1-磺酰基-2-酮.
DOI:10.1080/00397919708005006

专利信息

专利号:US-8153839-B2
优先权日:2005-09-14
标题:Method for synthesis of keto acids or amino acids by hydration of acetylene compound
发明人：OGO SEIJI; FUKUZUMI SHUN-ICHI
权利人:OGO SEIJI; FUKUZUMI SHUN-ICHI; JAPAN SCIENCE & TECH AGENCY
摘要:An object of the present invention is to provide a method for synthesis of keto acids by hydration of an acetylene compound (acetylene-carboxylic acids) under mild conditions free from harmful mercury catalysts and a method for synthesis of amino acids from acetylene-carboxylic acids in a single container (one-pot or tandem synthesis). In one embodiment of the method according to the present invention for synthesis of keto acids, acetylene-carboxylic acids is hydrated in the presence of a metal salt represented by General Formula (1), n nwhere M 1 represents an element in Group VIII, IX, or X of the periodic table, and X 1 , X 2 , or X 3 ligand represents halogen, H 2 O, or a solvent molecule, and k represents a valence of a cation species, and Y represents an anion species, and L represents a valence of the anion species, and each of K and L independently represents 1 or 2, and k×m=L×n.

专利号:US-6333441-B1
优先权日:1992-03-09
标题:Preparation of cis—olefins
发明人：SATO FUMIE; MIYAJI KATSUAKI; AMANO TAKEHIRO
权利人:NISSAN CHEMICAL IND LTD; SATO FUMIE
摘要:A cis-olefin of the formula: R 1 —CHâ•?CH—R 2 is prepared by reducing an alkyne of the formula: R 1 —C≡C—R 2 with formic acid in the presence of a palladium catalyst. R 1 and R 2 are independently selected from the group consisting of a hydrogen atom, ester group, substituted silyl group, carboxyl group, cyano group, aliphatic C1-C20 hydrocarbon group, and phenyl group. The cis-olefin which is a useful intermediate for the synthesis of fine chemicals is selectively produced in high yields.

专利号:US-8440608-B2
优先权日:2004-08-06
标题:Beta-substituted tetrandropyrana (on) s and method for the synthesis and the use thereof
发明人：MANE JEAN; CHANOT JEAN-JACQUES; SCHROEDER MARTIN
权利人:MANE JEAN; CHANOT JEAN-JACQUES; SCHROEDER MARTIN; MANE FILS V
摘要:The invention relates, in particular to a tetrahydropyran(on) compound which is substituted in position beta with respect to a cycle oxygen of formula (I), wherein a substituent R is a linear alkyl radical in C2:C10 including, (CH 3 ) 2 CH— or C 6 H 5 —(CH 2 ) m —, with m=0 or 1, or formula (II), wherein A is —CH 2 — or —CO—, in the form of an odorant and to a method for the synthesis thereof by reducing oxo-ester. The use of the inventive compound in composition such as perfumery compositions in the ordinary sense of the term i.e. topic, in particular cosmetic compositions and care products.

专利号:US-6531470-B1
优先权日:1998-01-23
标题:Oxazolidinone combinatorial libraries, compositions and methods of preparation
发明人：GORDEEV MIKHAIL F; LUEHR GARY W; PATEL DINESH V; NI ZHI-JIE; GORDON ERIC
权利人:UPJOHN CO
摘要:Oxazolidinones and methods for their synthesis are provided. Also provided are combinatorial libraries comprising oxazolidinones, and methods to prepare the libraries. Further provided are methods of making biologically active oxazolidinones as well as pharmaceutically acceptable compositions comprising the oxazolidinones. The methods of library preparation include the attachment of oxazolidinones to a solid support. The methods of compound preparation in one embodiment involve the reaction of an iminophosphorane with a carbonyl containing polymeric support.

专利号:US-6562844-B2
优先权日:1998-01-23
标 题:Oxazolidinone combinatorial libraries, compositions and methods of preparation
发明人：GORDEEV MIKHAIL F; LUEHR GARY W; PATEL DINESH V; NI ZHI-JIE; GORDON ERIC
权利人:UPJOHN CO
摘要:Oxazolidinones and methods for their synthesis are provided. Also provided are combinatorial libraries comprising oxazolidinones, and methods to prepare the libraries. Further provided are methods of making biologically active oxazolidinones as well as pharmaceutically acceptable compositions comprising the oxazolidinones. The methods of library preparation include the attachment of oxazolidinones to a solid support. The methods of compound preparation in one embodiment involve the reaction of an iminophosphorane with a carbonyl containing polymeric support.

专利号:US-6583315-B2
优先权日:2000-12-23
标 题:Process for preparing ethanebis(alkylphosphinic) acids
发明人：SICKEN MARTIN; WEFERLING NORBERT; SCHMITZ HANS-PETER
权利人:CLARIANT GMBH
摘要:The invention relates to a process for preparing ethanebis(alkylphosphinic) acids by n a) reacting elemental yellow phosphorus with alkyl halides in the presence of alkali metal hydroxide or of alkaline earth metal hydroxide to give a mixture whose main constituents are the alkali metal salts and/or alkaline earth metal salts of alkylphosphonous, phosphorous, and hypophosphorous acid, n b) liberating alkylphosphonous, phosphorous, and hypophosphorous acid by adding mineral acids, and also at the same time precipitating the alkali metal ions and, respectively, alkaline earth metal ions in the form of their salt of the mineral acids, and then n c) esterifying the alkylphosphonous acid from the mixture of the alkylphosphonous, phosphorous, and hypophosphorous acid, n d) isolating the ester of alkylphosphonous acid from the mixture and hydrolyzing the same to give alkylphosphonous acid, and n e) preparing, from the alkylphosphonous acid, the corresponding ethanebis(alkylphosphinic) acid of the general formula (I) where R 1 and R 2 may be identical or different and are hydrogen, a carboxy group, a carboxylic acid derivative, an unsubstituted or substituted alkyl group having from 1 to 10 carbon atoms, phenyl, benzyl, or alkyl-substituted aromatics, and R 3 and R 4 are identical or different and are an unsubstituted or substituted alkyl group having from 2 to 20 carbon atoms, by free-radical-initiated reaction with alkynes, and also to the use of the ethanebis(alkylphosphinic) acids prepared by this process as starting material for preparing flame retardants and precursors for the synthesis of other phosphorus-containing compounds.