专利号:WO-2005121154-A1 优先权日:2004-06-08 标 题:Process for the preparation of cefdinir 发明人:KUMAR RAAJ 权利人:TEVA PHARMA; TEVA PHARMA; KUMAR RAAJ 摘要:Provided are intermediates for use in synthesis of Cefdinir and processes for preparing cefdinir with such intermediates.
专利号:US-9296709-B2 优先权日:2012-07-03 标 题 :Manufacture of 2-(5-bromo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-ylthio)acetic acid 发明人:GUNIC ESMIR; GALVIN GABRIEL 权利人:ARDEA BIOSCIENCES INC 摘要:Described herein are certain processes for the synthesis of compounds of Formula (I):
专利号:US-5436368-A 优先权日:1990-10-31 标题:Intermediates in the preparation of 4,5-difluoroanthranillic acid 发明人:BRAISH TAMIM F 权利人:PFIZER 摘要:Compounds of the formula ##STR1## which are intermediates in the preparation of 4,5-difluoroanthranilic acid, an intermediate itself in the synthesis of quinolone antibacterials, and methods of preparing these intermediates.
专利号:WO-2006097348-A1 优先权日:2005-03-15 标 题:Use of agents such as nonpolymeric nitric oxide donors for making the lips full again and/or colouring the lips 发明人:CALS-GRIERSON MARIE-MADELEINE 权利人:OREAL; CALS-GRIERSON MARIE-MADELEINE 摘要:The invention relates in particular to the cosmetic use (i) of at least one agent for promoting the production of NO in and/or on the lips, chosen from nitric oxide NO donors or precursors; nonpolymeric NO releasers; and NO synthase synthesis and/or activity stimulators; or (ii) of other agents for promoting microcirculation in the skin, chosen from potassium channel openers; calcium channel blockers; phosphodiesterase inhibitors; flavonoids; vasodilator peptides that are not NO donors; temperature modulators; agents for promoting the stimulation and/or maintenance of angiogenesis; agents for promoting the stimulation of endothelial cell proliferation; agents for promoting endothelial cell migration; and mixtures thereof, in a makeup and/or care composition for the lips, as an agent for naturally making the lips full again and/or naturally coloring the lips. It also relates to specific care and/or makeup compositions for the lips containing said agent, and also to a cosmetic process aimed at making the lips naturally full and/or colored, using said compositions .
专利号:WO-9008142-A1 优先权日:1989-01-23 标题 :SYNTHESIS AND APPLICATION OF 1,3,6,8- AND 2,4,6,8-SUBSTITUTED DIBENZOFURANS AND DIBENZO-p-DIOXINS AS ANTITUMORIGENIC AGENTS 发明人:SAFE STEPHEN H 权利人:TEXAS A & M UNIV SYS 摘要:Novel 2,4,6,8- and 1,3,6,8-substituted dibenzofurans and dibenzo-p-dioxins, the preparation thereof and the use thereof as antiestrogens in the treatment of estrogen dependent tumors.
专利号:US-5516790-A 优先权日:1989-01-23 标题:Synthesis and application of alkyl-substituted dibenzofurans as antitumorigenic agents 发明人:SAFE STEPHEN H 权利人:TEXAS A & M UNIV SYS 摘要:Provided is a method of inhibiting estrogen activity by administering a biologically active amount of a substituted dibenzofuran or substituted dibenzodioxin.
摘要:Farmaco, Edizione Scientifica., 11(855), 1956 参考文献:10.1007/bf01616318|10.1007/s005479900180|10.1055/s-0031-1276200 摘要:Davies RR, Coady MA, Hammond GL, Elefteriades JA, Gusberg RJ. Low molecular weight heparin: An evaluation of current and potential clinical utility in surgery. International Journal of Angiology. 1999 Sep;8(4):203–15. doi: 10.1007/bf01616318.