CAS: 327-75-3; 1-Bromo-2,4-Bis(Trifluoromethyl)Benzene

上下游产品

CAS号577-05-9 1-Methoxy-2,4-b... | CAS号402-31-3 间二三氟甲苯 | CAS号109-65-9 正溴丁烷 | CAS号306936-81-2 ETHYL 2-(2,4-BI... | CAS号153254-09-2 2,4-双(三氟甲基)苯硼酸 | CAS号88444-80-8 2-[2,4-bis(trif...

间二三氟甲苯置于2,2,6,6-四甲基哌啶,正丁基锂,四溴化碳体系中,用 四氢呋喃,正己烷,二氯甲烷 用作溶剂,化学反应 2.0H,以92%的收率获得2,4-双(三氟甲基)溴苯
参考文献:New Strategies In The Synthesis Of Regioselectively Trifluoromethyl-And Trifluoromethoxy-Substituted Arenes As Building Blocks For Biologically Active Molecules
标题:New Strategies In The Synthesis Of Regioselectively Trifluoromethyl-And Trifluoromethoxy-Substituted Arenes As Building Blocks For Biologically Active Molecules
摘要:Regioisomerically Pure Trifluoromethyl-And Trifluoromethoxy-Substituted Aromatic And Heteroaromatic Aldehydes And Carboxylic Acids Are Valuable Building Blocks For The Synthesis Of Biologically Active Molecules. They Have Been Prepared By Employing Modem Organometallic Methods. On This Basis,A Novel Access To 2,3-Dihydro-5-(Trifluoromethoxy)Indole Was Developed Which Represents An Intriguing Example Of How Organometallic And Radical Chemistry Can Fecundate Each Other. (C) 2002 Elsevier Science B.V. All Rights Reserved.
Doi:10.1016/s0022-1139(02)00161-6

专利信息

专利号:US-6255545-B1
优先权日:1999-06-11
标 题 :Process for the synthesis of 3,5-bis(trifluoromethyl)-bromobenzene
发明人：CVETOVICH RAYMOND; TSAY FUH-RONG
权利人:MERCK & CO INC
摘要:The present invention is concerned with a novel process for the preparation of 3,5-bis(trifluoromethyl)bromobenzene (CAS 328-70-1). This compound is useful as an intermediate in the synthesis of compounds which possess pharmacological activity.

专利号:AU-5472500-A
优先权日:1999-06-11
标题 :Process for the synthesis of 3,5-bis(trifluoromethyl)-bromobenzene

专利号:CA-2374595-A1
优先权日:1999-06-11
标 题:Process for the synthesis of 3,5-bis(trifluoromethyl)-bromobenzene