CAS: 26501-54-2; Tetrabutylammonium Nitrite

该化合物是四丁基铵盐,其特点是四丁基聚氨酸和亚硝酸阴离子,一般是白色到浅黄色晶状固体,可溶于极有机溶剂,如甲醇和丙硝酸盐,但在水中溶解性有限.该化合物以其作为分阶段转移催化剂的作用而著称,它促进有机物质和无机物质在不同阶段的反应.四丁基硝酸也可以作为有机合成的试剂,特别是在硝酸化合物的制备过程中.必须谨慎地处理该物质,因为硝酸盐可能有毒和潜在危险.此外,TBA-NO2在一定条件下可以分解,释放氮氧化物,这就需要适当的储存和处理程序来确保安全.

结构式图片

欧盟法规

ECHA物质ECHA物质C&L通报REACH预注册

上下游产品

tetrabutylammomium bromide tetrabutyl ammonium fluoridetetrabutylammonium nitrate naphthalene-1-carboxylic acid butyl ester nitrogen(II) oxide

合成工艺路线路线简述

    📜四丁基溴化铵置于potassium Nitrite体系中,用 水 用作溶剂,化学反应生成四丁基亚硝酸铵
    参考文献:部分[n+4444]基离子液体的离子交换合成及热特性
    标题:部分[n+4444]基离子液体的离子交换合成及热特性
    摘要:摘要 使用四丁基铵阳离子 [n + 4444 ] 和无机阴离子如 Bf 4-,No 3-,No 2-,Scn-,Bro 3-,Io 3-,Pf 6-和 Hco 3-合成了八种盐.离子交换法.使用热重法,差示扫描量热法和红外光谱法对这些离子液体 (Il) 进行了表征.热物理性质,如密度,体积膨胀,熔化热,固-固转变热,比热容和热能储存能力被确定.在某些情况下,在熔点以下观测到的固-固转变的总热量超过了熔化热.在固相和液相中测定样品的热导率.
    Doi:10.1016/j.Tca.2013.01.003

    海关参考信息

    专利信息


    专利号:US-10851130-B2
    优先权日:2018-01-29
    标题:Chemical synthesis method of Plesiomonas shigelloides serotype O51 O-antigen oligosaccharide
    发明人:YIN JIAN; HU JING; SEEBERGER PETER; QIN CHUNJUN
    权利人:UNIV JIANGNAN; MAX PLANCK INST OF COLLOIDS AND INTERFACES
    摘要:The present disclosure discloses the chemical synthesis method of the Plesiomonas shigelloides serotype O51 O-antigen oligosaccharide, belonging to the field of chemistry. Source-abundant D-glucose, L-fucose, D-glucosamine and the like are used as raw materials to prepare three glycosylation building blocks, the synthetic route composed of 11 reaction modules is designed, and through the optimization of protecting group and the optimization of the time of introducing functional group, the preparation of the target oligosaccharide chain is successfully achieved. The oligosaccharide chain prepared in the present disclosure has the advantages of cheap and easy-to-get raw materials, and simple and easy-to-repeat preparation method. The present disclosure will have good application prospects in the aspects of development of new drugs and vaccines of Plesiomonas shigelloides , and the like.

    专利号:US-8697862-B2
    优先权日:2008-05-16
    标题 :Synthesis of galactoside inhibitors
    发明人:NILSSON ULF
    权利人:NILSSON ULF; GALECTO BIOTECH AB
    摘要:Novel synthesis routes for preparation of thiodigalactosides and intermediates are presented. The method includes the use of a 3-azido-galactosyl thiouronium salt derivative, which is activated to the corresponding thiol in situ, which in turn is directly reacted with a 3-azido-galactosyl bromide resulting in the 3,3′-di-azido-thio-di-galactoside before the thiol has a chance to reduce the azido 10 group. Hence, in situ formation of the 3-azido-galactosyl thiol from the thiouronium salt is essential in the synthesis procedure, because any other method that generate the thiol separately results in extensive unwanted azide reduction.

    专利号:US-2024409571-A1
    优先权日:2023-06-08
    标 题:Chemoenzymatic synthesis of n-acetylated gangliosides and glycosphingosines
    发明人:CHEN XI; YU HAI; MISHRA BIJOYANANDA; ZHENG ZIMIN; AGRAHARI ANAND KUMAR; GUCCHAIT ARIN
    权利人:UNIV CALIFORNIA
    摘要:Described herein are novel stable 9-N-, 8-N-, and 7-N-acetyl analogues of instable 9-O-acetyl, 8-O-acetyl, and 7-O-acetyl b-series gangliosides and glycosphingosines, including GD3, GD2, GD1b, GT1b, GQ1b, and their glycosphingosines. Chemoenzymatic methods for the production of the stable 9-N-, 8-N-, and 7-N-acetyl analogues are also described herein.

    专利号:WO-2009139719-A9
    优先权日:2008-05-16
    标 题 :Novel synthesis of galactoside inhibitors

    专利号:CA-2724064-C
    优先权日:2008-05-16
    标题 :Synthesis of galactoside inhibitors

    专利号:WO-2018002957-A2
    优先权日:2016-06-29
    标题 :A method for synthesis of 6-deoxy-l-hexoses from l-rhamnose

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    主要参考文献

    参考标题:Copper-Catalyzed Synthesis Of Esters From Ketones. Alkyl Group As A Leaving Group
    作者:Yuji Nakatani,Yuichiro Koizumi,Ryu Yamasaki,Shinichi Saito |发布日期:2008.5.1
    摘要:The Conversion Of Ketones To Esters Has Been Achieved Through The Use Of Cu Catalyst And Tetrabutylammonium Nitrite. This Reaction Involves The Activation Of The Less Activated C-C Bond, And The Alkyl Group Is Removed As A Leaving Group. Various Isopropyl Ketones Are Found To Be Good Substrates For This Reaction.

    合成参考文献


    摘要:Chand, K.; Umesh; Dorairaj, D. P.; Hsu, S. C. N., Science of Synthesis Knowledge Updates, (2021) 2, 271.
    📝 需求与反馈
    尽可能描述清楚需求与问题信息
    ×

    通知