CAS: 2420-16-8; 3-Chloro-4-Hydroxybenzaldehyde

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CAS号123-08-0 4-羟基苯甲醛; 对羟基苯甲醛 | CAS号6640-27-3 2-氯-4-甲酚 | CAS号105960-29-0 3-氯-4-羟基苄醇 | CAS号100-39-0 溴化苄 | CAS号67-66-3 氯仿 | CAS号95-57-8 邻氯苯酚 | CAS号3964-57-6 3-氯-4-羟基苯甲酸甲酯 | CAS号507-40-4 次氨酸叔丁基酯 | CAS号68243-92-5 2,2,2-trichloro... | CAS号141805-79-0 2-chloro-4-(chl... | CAS号105960-29-0 3-氯-4-羟基苄醇 | CAS号141805-79-0 2-chloro-4-(chl... | CAS号1849-76-9 3-溴-5-氯-4-羟基苯甲醛 | CAS号185527-66-6 methyl 3-(3-chl... | CAS号2315-81-3 3-氯-4-羟基苯甲腈 | CAS号1239610-72-0 5-[[3-Chloro-4-... | CAS号4903-09-7 3-氯-4-甲氧基苯甲醛 | CAS号161565-36-2 3-溴-5-氯-4-甲氧基苯(甲)醛 | CAS号16231-54-2 Ethyl (2-chloro... | CAS号117490-57-0 4-(苄氧基)-2-氯苯甲醛

3-氯-4-羟基苯甲酸置于氯化亚砜,2,3-二氯-5,6-二氰基-1,4-苯醌,Lithium Hexamethyldisilazane体系中,用 四氢呋喃,1,4-二氧六环,甲醇 用作溶剂,化学反应 6.0H,反应生成3-氯-4-羟基苯甲醛
参考文献:Prodrugs Of Fused-Bicyclic C5Ar Antagonists
标题:Prodrugs Of Fused-Bicyclic C5Ar Antagonists
摘要:本公开提供了化合物ia,Ib,Ic,Iia,Iib和iic的结构,或其在药学上可接受的盐,这些化合物是c5A受体的调节剂.还提供了包括治疗涉及c5A病理性激活的疾病或疾病的药物组合物和使用方法,以及非药物应用.

专利信息

专利号:US-5877296-A
优先权日:1994-06-03
标题:Process for preparing conjugates of methyltrithio antitumor agents
发明人：HAMANN PHILIP ROSS; HINMAN LOIS; HOLLANDER IRWIN
权利人:AMERICAN CYANAMID CO
摘要:This invention describes carrier-drug conjugates prepared from disulfide analogs of the calicheamicin family of potent antitumor antibiotics and their derivatives, as well as similar analogs from related antitumor antibiotics such as the esperamicins. The carrier can be an antibody, growth factor, or steroid which targets an undesired population of cells, such as those of a tumor. Whole protein carriers as well as their antigen-recognizing fragments and their chemically or genetically manipulated counterparts are useful for the targeting portion of the conjugates. This invention includes compounds required for the synthesis of these conjugates, appropriate pharmaceutical compositions of the carrier-drug conjugates, and their method of use.

专利号:US-9919064-B2
优先权日:2012-08-10
标 题 :Compositions, methods, and systems for the synthesis and use of imaging agents
发明人：CESATI RICHARD R; RADEKE HEIKE S; PANDEY SURESH K; PUROHIT AJAY; ROBINSON SIMON P
权利人:LANTHEUS MEDICAL IMAGING INC
摘要:The present invention provides compounds with imaging moieties for imaging a subject. The present invention also relates to systems, compositions, and methods for the synthesis and use of imaging agents, or precursors thereof. An imaging agent precursor may be converted to an imaging agent using the methods described herein. In some cases, a composition or plurality of imaging agents is enriched in 18 F. In some cases, an imaging agent may be used to image an area of interest in a subject, including, but not limited to, the heart, cardiovascular system, cardiac vessels, brain, and other organs.

专利号:US-11976052-B2
优先权日:2019-01-11
标题:Leukotriene synthesis inhibitors
发明人：BURGOYNE DAVID L; DEBRUIN ERIN; FONAREV JULIA; YEE JAMES GEE KEN; LANGLANDS JOHN MICHAEL
权利人:NAEGIS PHARMACEUTICALS INC
摘要:Provided are specific leukotriene synthesis inhibitor compounds and pharmaceutical compositions comprising the compounds and methods of using the compounds and the pharmaceutical compositions in treating, for example, inflammatory diseases or conditions.

专利号:US-5739116-A
优先权日:1994-06-03
标题:Enediyne derivatives useful for the synthesis of conjugates of methyltrithio antitumor agents

专利号:US-2008281105-A1
优先权日:2005-01-18
标题:Novel Quinolinium Salts and Derivatives
发明人：MACDONALD JAMES E; HYSELL MICHELLE K; YU DEHUA; LI HENRY; WONG-STAAL FLOSSIE
权利人:IMMUSOL INC
摘要:The present invention relates generally to the synthesis of novel quinolinium salts and derivative compounds. Such salts and compounds are useful for inhibiting the growth of cancer cells.

专利号:IL-132974-A
优先权日:1994-06-03
标 题:Compounds useful in the synthesis of conjugates of methyltrithio anti-tumour agents