[(2E)-Cyclooct-2-En-1-Yl] 3-Oxo-2,4-Diphenylbutanoate置于二甲基-1,2,4,5-四嗪体系中,用 氯仿 用作溶剂,化学反应 1.0H,反应生成二苄基甲酮 参考文献: Activatable Liposomes[fr] Liposome Pouvant être Actif 标题: Activatable Liposomes[fr] Liposome Pouvant être Actif 摘要:揭示了一种反应性脂质体,包括一个脂质双层包裹的腔隙,其中该双层包括与一个含有八个成员的非芳香环烯基基团连接的连接,最好是环辛烯基团,更好是反式环辛烯基团.这些脂质体用于一种工具包,该工具包包括直接或间接地与一个触发器连接的脂质体,以及用于触发器的活化剂,其中触发器包括一个含有八个成员的非芳香环烯基基团,而活化剂包括一个二烯.
专利信息
专利号:US-11161827-B2 优先权日:2019-04-05 标 题 :Catalytic systems for stereoselective synthesis of chiral amines by enantiodivergent radical C—H amination 发明人:Zhang xiao-xiang; Lang kai 权利人:TRUSTEES BOSTON COLLEGE; THE TRUSTEES OF BOSTON COLLEGE 摘要:In one aspect, the disclosure relates to a mode of asymmetric induction in radical processes based on sequential combination of enantiodifferentiative H-atom abstraction and stereoretentive radical substitution. Also disclosed is an asymmetric system for stereoselective synthesis of strained 5-membered cyclic sulfamides via radical 1,5-C—H amination of sulfamoyl azides. The disclosed metalloradical system can control the degree and sense of asymmetric induction in the catalytic radical C—H amination in a systematic manner. The disclosed system is applicable to a broad scope of substrates with different types of C(sp 3 )—H bonds and exhibits reactivity and selectivity, providing access to both enantiomers of useful 5-membered cyclic sulfamides in a highly enantioenriched form. Also disclosed are catalysts useful in these processes. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure.
专利号:US-4936966-A 优先权日:1987-12-18 标题:Process for the electrochemical synthesis of alpha-saturated ketones 发明人:GARNIER LAURENCE; ROLLIN YOLANDE; PERICHON JACQUES 权利人:POUDRES & EXPLOSIFS STE NALE 摘要:The present invention relates to a process for the electrochemical synthesis of alpha-saturated ketones by electrochemical reduction, in an organic solvent medium, of alpha-saturated organic halides in the presence of CO2 and of a catalyst based on nickel complexed with a bidentate organic ligand containing two nitrogen atoms, such as 2,2'-bipyridine and, optionally, with an ethylenic coligand. The anode, made of a metal chosen from the group consisting of the reducing metals and their alloys, is consumed during the electrochemical reaction whose site it is. It is preferably made of magnesium. This process is simple to use and allows a single-compartment cell to be employed. Alpha-saturated ketones are compounds commonly employed in the chemical industry, particularly as solvents or synthesis intermediates.
专利号:US-2006211858-A1 优先权日:2001-02-28 标 题 :Novel substituted calix (4) pyrroles and process for the synthesis of calix (4) pyrroles over molecular sieve catalysts 发明人:RAGHAVAN KONDAPURAM V; KULKARNI SHIVANAND J; KISHAN MOTKURI R; SRINIVAS NAGABANDI 权利人:RAGHAVAN KONDAPURAM V; KULKARNI SHIVANAND J; KISHAN MOTKURI R; SRINIVAS NAGABANDI 摘要:The present invention relates to novel calix pyrroles and a process for synthesis of calix (4) pyrroles by reacting pyrrole with cyclic or acyclic ketones in dichloro methane (DCM) solvent over molecular sieve catalysts which provides an eco-friendly, more economical and selective heterogeneous method.
专利号:US-10487099-B2 优先权日:2017-06-30 标 题:Synthesis of hypervalent iodine reagents with dioxygen 发明人:POWERS DAVID CHARLES; MAITY ASIM; HYUN SUNG-MIN 权利人:TEXAS A & M UNIV SYS 摘要:Methods of synthesis of hypervalent iodine reagents and methods for oxidation of organic compounds are disclosed.
专利号:US-6605194-B2 优先权日:2001-02-26 标 题:Substituted calix (4) pyrroles and process for the synthesis of calix (4) pyrroles over molecular sieve catalysts 发明人:RAGHAVAN KONDAPURAM VIJAYA; KULKARNI SHIVANAND JANARDAN; KISHAN MOTKURI RADHA; SRINIVAS NAGABANDI 权利人:COUNCIL SCIENT IND RES 摘要:The present invention relates to novel calix pyrroles and a process for synthesis of calix (4) pyrroles by reacting pyrrole with cyclic or acyclic ketones in dichloro methane (DCM) solvent over molecular sieve catalysts which provides an eco-friendly, more economical and selective heterogeneous method.
专利号:US-4502994-A 优先权日:1982-12-09 标题 :Enantiomeric synthesis of 3-amino-4-carbamoyloxymethyl-2-azetidonone-1-sulfate 发明人:WEI CHUNG-CHEN; WEIGELE MANFRED 权利人:HOFFMANN LA ROCHE 摘要:A novel enantiomeric synthesis from ascorbic acid of (3S,4S)-3-amino-4-carbamoyloxymethyl-2-azetidinone-1-sulfate, an intermediate for an antibiotic compound.
[参考文献]: Eun Jin Lim, Et Al. Tunicamycin Promotes Apoptosis In Leukemia Cells Through Ros Generation And Downregulation Of Survivin Expression. Apoptosis. 2015 Aug;20(8):1087-98.
合成参考文献
参考文献:10.1107/s1600536811017284 摘要:Ali AJ, Athimoolam S, Bahadur SA, Raja VP. 2,6-Bis(2-chloro-phen-yl)-4-oxo-3,5-diphenyl-heptane-1,1,7,7-tetra-carbo-nitrile. Acta Crystallogr Sect E Struct Rep Online. 2011 Jun 01;67(Pt 6):o1407–8.