CAS: 64849-39-4; (2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(Hydroxymethyl)Tetrahydro-2H-Pyran-2-Yl (9S,11Ar,11Bs)-4,11B-Dimethyl-8-Methylene-9-(((2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(Hydroxymethyl)Tetrahydro-2H-Pyran-2-yl)Oxy)Tetradecahydro-6A,9-Methanocyclohepta[a]Naphthalene-4-Carboxylate

上下游产品

CAS号492-61-5 β-D-葡萄糖 | CAS号471-80-7 甜菊醇 | CAS号60129-60-4 Steviolmonoside | CAS号572-09-8 2,3,4,6-四乙酰氧基-a...

📜甜菊糖置于immobilized β-Galactosidase From Escherichia Coli Bl21 (De3) Plyss体系中,化学反应生成 甜叶悬钩子苷
参考文献:Anti-Cariogenic Characteristics Of Rubusoside
标题:Anti-Cariogenic Characteristics Of Rubusoside
摘要:变形链球菌通过变形蔗糖酶活性从蔗糖合成粘性不溶性葡聚糖,从而在人类龋齿的发展中发挥重要作用.为了探讨蔷薇科悬钩子中天然甜味剂成分甜叶悬钩子苷 (Ru) 的抗龋齿特性,我们研究了 Ru 对变异蔗糖酶活性和变异链球菌生长的抑制作用. Ru (50 Mm) 对含有 500 Mm 蔗糖的 0.1 U/ml 变形链球菌变异蔗糖酶显示出 97% 的抑制活性.它表现出竞争性抑制,Ki 值为 1.1 +/-0.2 Mm,Ic50 为 2.3 Mm.根据分子对接分析,其抑制活性归因于疏水性和氢键相互作用. Ru 作为抑菌剂抑制变形链球菌的生长,Mic 和 Mbc 值分别为 6 Mm 和 8 Mm.此外,Ru与姜黄素结合时表现出协同抗菌活性.因此,Ru是一种天然的抗龋齿剂,具有抗变异蔗糖酶活性和对变异链球菌的抗菌活性.
DOI:10.1007/s12257-018-0408-0

专利信息

专利号:US-10533205-B1
优先权日:2013-10-09
标 题:Kaurenoic acid glycoside precursors and methods of synthesis
发明人：ZIPP BRANDON
权利人:VITALITY BIOPHARMA INC
摘要:Ent-kaurenoic acid glycoside precursor compositions and synthesis methods are provided. The KA-19-monoside, KA-19-bioside and KA-19-trioside precursors can be used as starting materials for a variety of kaurenoic acid based reactions. The precursors provide alternative synthesis pathways for steviol glycosides to the natural pathway based on Steviol biosynthesis. The alternative synthesis pathways using the precursors also circumvent the rate limiting step of the natural Steviol biosynthesis pathway. The precursors can be used individually or in combination to produce a mixture or individual steviol glycosides such as Rebaudioside A, Rebaudioside D or Rebaudioside M. Control over the precursor quantities and composition allows control over the composition of the resulting steviol glycosides that are finally produced.

专利号:US-12071646-B2
优先权日:2014-09-11
标 题 :Cells comprising mogroside pathway enzymes and uses thereof
发明人：ITKIN MAXIM; DAVIDOVICH-RIKANATI RACHEL; COHEN SHAHAR; PORTNOY VITALY; DORON-FAIGENBOIM ADI; PETREIKOV MARINA; SHEN SHMUEL; TADMOR YAAKOV; BURGER YOSEF; LEWINSOHN EFRAIM; KATZIR NURIT; SCHAFFER ARTHUR A; OREN ELAD
权利人:THE STATE OF ISRAEL MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT AGRICULTURAL RES ORGANIZATION ARO VO
摘要:Isolated mogroside and mogrol biosynthetic pathway enzyme polypeptides useful in mogroside biosynthesis are provided. Mogroside biosynthetic pathway enzymes of the invention include squalene epoxidase (SE), epoxy hydratase (EH), cytochrome p450 (Cyp), cucurbitadienol synthase (CDS) and udp-glucosyl-transferase (UGT), Also provided are methods of producing a mogroside using the isolated mogroside and mogrol biosynthetic enzyme polypeptides, the methods comprising contacting a mogrol and/or a glycosylated mogrol (mogroside) with at least one UDP glucose glucosyl transferase (UGT) enzyme polypeptide of the invention catalyzing glucosylation of the mogrol and/or the glucosylated mogrol to produce a mogroside with an additional glucosyl moietie(s), thereby producing the mogroside. Alternatively or additionally provided is a method of synthesizing a mogrol, the method comprising contacting a mogrol precursor substrate with one or more mogrol biosynthetic pathway enzyme polypeptides as described herein catalyzing mogrol synthesis from the mogrol precursor substrate, thereby synthesizing the mogrol.

专利号:BR-112017006139-B1
优先权日:2014-10-03
标题 :Method for the synthesis of rebaudioside m or rebaudioside m and rebaudioside m

专利号:CN-114507649-A
优先权日:2022-02-16
标 题 :Thermophilic enzymes and a one-pot method for the efficient synthesis of UDP-glucose and UDP-glucuronic acid

专利号:KR-102050863-B1
优先权日:2017-06-29
标 题 :Synthesis method of rubusoside-fructoside using levansucrase