专利号:WO-2005021521-A1 优先权日:2003-08-28 标题:Preparation of 1-[4-(2-methoxy-phenyl)-piperazin-1-yl]-3-(2,6-dioxopiperidin-1-yl) propane hydrochloride 发明人:ANAND NITYA; SINHA NEELIMA; JAIN SANJAY; MEHTA ANITA 权利人:RANBAXY LAB LTD; ANAND NITYA; SINHA NEELIMA; JAIN SANJAY; MEHTA ANITA 摘要:The present invention relates to processes for the synthesis of 1-[4-(2Âmethoxyphenyl)piperazin-1-yl]-3-(2,6-dioxopiperidin-1-yl) propane hydrochloride having protracted uro-selective (α1-adrenoceptor antagonistic activity. The compound holds promise for treating benign prostatic hyperplasia (BPH).
专利号:US-4670560-A 优先权日:1986-04-28 标 题:Thienopyrimidine-2,4-dione derivatives and intermediates thereof 发明人:PRESS JEFFERY B; RUSSELL RONALD K 权利人:ORTHO PHARMA CORP 摘要:The synthesis of thienopyrimidine-2,4-dione derivatives and their urea intermediates is described. The novel urea intermediates and thienopyrimidine-2,4-dione derivatives are generally vasodilating agents and anti-hypertensive agents. The compounds are useful as cardiovascular agents.
专利号:US-4707550-A 优先权日:1986-04-28 标题 :N-(substituted thienyl)-N'-(substituted piperazinyl)-ureas 发明人:PRESS JEFFERY B; RUSSELL RONALD K 权利人:ORTHO PHARMA CORP 摘要:The synthesis of thienopyrimidine-2,4-dione derivatives and their urea intermediates is described. The novel urea intermediates and thienopyrimidine-2,4-dione derivatives are general vasodilating agents and anti-hypertensive agents. The compounds are useful as cardiovascular agents.
专利号:US-4939137-A 优先权日:1989-06-28 标 题:Ring-fused thienopyrimidinedione derivatives 发明人:RUSSELL RONALD K; RAMPULLA RICHARD A 权利人:ORTHO PHARMA CORP 摘要:The synthesis of ring-fused thienopyrimidinedione derivatives is described. The novel ring-fused thienopyrimidinedione derivatives are generally vasodilating agents and antihypertensive agents and as such are useful as cardiovascular agents.
专利号:WO-2008144764-A1 优先权日:2007-05-21 标 题 :Compositions, synthesis, and methods of using quinolinone based atypical antipsychotic agents
专利号:AU-2008254585-B2 优先权日:2007-05-21 标 题:Compositions, synthesis, and methods of using quinolinone based atypical antipsychotic agents