专利号:US-5420237-A 优先权日:1991-08-29 标 题:Enzymatic synthesis of polyaniline 发明人:ZEMEL HAYA; QUINN JOHN F 权利人:ALLIED SIGNAL INC 摘要:This invention relates to a process for the enzymatic synthesis of electrically conductive substituted and unsubstituted polyanilines. Aniline monomer(s), an oxidizing agent, which comprises an enzyme and an electron acceptor, and an acidifying agent are reacted together to form polyanilines.
专利号:US-10022366-B2 优先权日:2013-04-23 标 题:Extending and maintaining micropore viability of microneedle treated skin with lipid biosynthesis inhibitors for sustained drug delivery 发明人:STINCHCOMB AUDRA L; GHOSH PRIYANKA 权利人:STINCHCOMB AUDRA L; GHOSH PRIYANKA; UNIV MARYLAND; UNIV KENTUCKY RES FOUND 摘要:Microneedles and their use as a physical skin permeation enhancement technique facilitate drug delivery across the skin in therapeutically relevant concentrations. Micropores created in the skin by MNs reseal because of normal healing processes of the skin, thus limiting the duration of the drug delivery window. Pore lifetime enhancement strategies can increase effectiveness of MNs as a drug delivery mechanism by prolonging the delivery window. Fluvastatin (FLU) was used to enhance pore lifetime by inhibiting the synthesis of cholesterol, a major component of the stratum corneum lipids. The skin recovered within a 30-45-min time period following the removal of occlusion, and there was no significant irritation observed due to the treatment compared to the control sites. Thus, it can be concluded that localized skin treatment with FLU can be used to extend micropore lifetime and deliver drugs for up to 7 days across MN-treated skin.
专利号:US-4889948-A 优先权日:1987-08-18 标题:Acrylate ester ether derivatives 发明人:MATHIAS LON J; KUSEFOGLU SELIM H 权利人:UNIV SOUTHERN MISSISSIPPI 摘要:A process for synthesizing ethers of alkyl alpha(hydroxymethyl)-acrylate by reacting alkyl acrylate and formaldehyde in the presence of a DABCO catalyst. The ethers may be used as cross-linking agents for thermoplastic polymers. Further, these ethers in turn enable synthesis of cyclopolymers that may show promising biological activity.
专利号:KR-20090102733-A 优先权日:2006-12-27 标 题 :Method for synthesis of hyperbranched polymer, hyperbranched polymer, resist composition, semiconductor integrated circuit, and method for production of semiconductor integrated circuit
专利号:KR-20090103860-A 优先权日:2006-12-28 标题:Process for synthesis of hyperbranched polymer, hyperbranched polymer, resist compositions, semiconductor integrated circuits, and process for production of semiconductor integrated circuits
专利号:US-4999410-A 优先权日:1987-08-18 标 题 :Acrylate ester ether derivatives 发明人:MATHIAS LON J; KUSEFOGLU SELIM H 权利人:UNIV SOUTHERN MISSISSIPPI 摘要:A process for synthesizing ethers of alkyl alpha-(hydroxymethyl)-acrylate by reacting alkyl acrylate and formaldehyde in the presence of a DABCO catalyst. The ethers may be used as cross-linking agents for thermoplastic polymers. Further, these ethers in turn enable synthesis of cyclopolymers that may show promising biological activity.
参考文献:10.1007/s11655-022-3572-1 摘要:Ren Y, Cui G, He L, Yao H, Zi C, Gao Y. Traditional Uses, Phytochemistry, Pharmacology and Toxicology of Rhizoma phragmitis: A Narrative Review. Chinese Journal of Integrative Medicine. 2022 Mar 23;28(12):1127–36. doi: 10.1007/s11655-022-3572-1.