CAS: 5048-19-1; 5-Hexenenitrile

相似化合物

1577-22-6 1572-52-7 592-51-8

上下游产品

cyclohexanone-oxime 5-hexynonitrile carbon dioxide 1-methyl-adiponitrile hex-5-en-1-amine 1-cyclohexylhex-5-en-1-one benzyl 4-pentenyl ketone

📜环己酮肟置于磷酸,氮,Silica Gel体系中,化学反应生成 5-己烯腈
参考文献:De1015426
标题:De1015426

专利信息

专利号:US-3944619-A
优先权日:1976-02-20
标 题 :Synthesis of d-2-amino-1-butanol
发明人：SINGH BALWANT
权利人:AMERICAN CYANAMID CO
摘要:D-2-Amino-1-butanol, for the synthesis of ethambutol hydrochloride, d,d'-2,2'-(ethylenediimino)di-1-butanol dihydrochloride, is produced in high purity and good yields by the reaction of butene-1, a nitrile, preferably an excess of acetonitrile, and chlorine to form N-[1-(chloromethyl)propyl]acetimidoyl chloride which is hydrolyzed to dl-2-amino-1-butanol, which can be isolated as the hydrochloride, or free base, or a mixture, resolved with L(+)- tartaric acid and the d-2-amino-1-butanol reacted with ethylene dichloride and then hydrochloric acid to form ethambutol hydrochloride. A minimum of by-products which are conveniently split out permits the economical synthesis of a pharmaceutical grade product.

专利号:US-4927924-A
优先权日:1989-04-14
标 题:Synthesis of caprolactam
发明人：BELL WELDON K; HAAG WERNER O
权利人:MOBIL OIL CORP
摘要:A process is provided for catalytically converting cyclohexanone oxime to epsilon caprolactam. The conversion is characterized by exceptionally high selectivity and reduced rate of catalyst aging, even at single pass conversion above 90 percent. The conversion catalyst is a medium pore size crystalline zeolite exemplified by ZSM-5 which has low acid activity. Recycling unconverted oxime provides excellent ultimate yield of caprolactam.

专利号:US-5292880-A
优先权日:1992-05-11
标题:Synthesis of caprolactam using catalysts
发明人：APELIAN MINAS R; BELL WELDON K; FUNG ANTHONY S; HAAG WERNER O; VENKAT CHAYA
权利人:MOBIL OIL CORP
摘要:A process for catalytically converting cyclohexanone oxime to epsilon caprolactam. The conversion catalyst is a crystalline aluminosilicate zeolite having a Constraint Index greater than 1 and a reduced surface acidity. The surface acidity is reduced by selective surface dealumination of the crystalline aluminosilicate zeolite by contacting the zeolite with dicarboxylic acid, such as oxalic acid.

专利号:US-8216999-B2
优先权日:2005-07-20
标题 :HCV NS3 protease inhibitors
发明人：HOLLOWAY M KATHARINE; LIVERTON NIGEL J; LUDMERER STEVEN W; MCCAULEY JOHN A; OLSEN DAVID B; RUDD MICHAEL T; VACCA JOSEPH P; MCINTYRE CHARLES J
权利人:HOLLOWAY M KATHARINE; LIVERTON NIGEL J; LUDMERER STEVEN W; MCCAULEY JOHN A; OLSEN DAVID B; RUDD MICHAEL T; VACCA JOSEPH P; MCINTYRE CHARLES J; MERCK SHARP & DOHME
摘要:The present invention relates to macrocyclic compounds of formula (I) that are useful as inhibitors of the hepatitis C virus (HCV) NS3 protease, their synthesis, and their use for treating or preventing HCV infections.