CAS: 4423-94-3; 2-Ethylcyclohexan-1-One

该化合物是具有分子式C8H14O的圆锥酮,在环环状环的2位置上有一个乙基替代体,该化合物通常用作有机合成的中间体,特别是在香料,药品和特殊化学品的生产中,其结构特性,包括反应性碳基组和烷基侧链的存在,使它成为进一步功能化的多功能构件.该化合物在普通有机溶剂中表现出中等的波动性和溶解性,便于在各种反应条件下使用,在标准处理条件下保持稳定,并具有良好的再活动特征,有助于其在工业和研究应用中的效用.

结构式图片

相似化合物

583-60-8 22617-19-2 3760-20-1

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上下游产品

o-Hydroxyethylbenzene 2-ethylidenecyclohexan-1-one diethyl ether c-chloro-cyclohexan-r-ol(+/-)-1-ethyl-2c-chloro-cyclohexan-r-ol 2-ethyl-6-dimethylaminomethyl-cyclohexanone 2,2-diethylcyclohexanone 2-ethyl-2-butyl-cyclohexanone (+)-(1S,2R)-2-ethylcyclohexanol

合成工艺路线路线简述

  • 合成目标产物 2-Ethylcyclohexanone 主要起始原料 Cyclooctanone
  • (文献来源)合成步骤主要原料 Cyclooctanone
📜2-乙酰基环己酮置于alkaline Solution,Potassium Ethoxide体系中,化学反应生成 2-乙基环己酮
参考文献:Leser,Comptes Rendus Hebdomadaires Des Seances De L'Academie Des Sciences,1905,Vol. 141,P. 1033
标题:Leser,Comptes Rendus Hebdomadaires Des Seances De L'Academie Des Sciences,1905,Vol. 141,P. 1033

海关参考信息

专利信息


专利号:US-4256639-A
优先权日:1978-06-23
标题:Process for the synthesis of isatin derivatives
发明人:BAIOCCHI LEANDRO
权利人:ACRAF
摘要:Process for the preparation of the 2-(2,6-dichloroanilino)-phenylacetic acid which comprises, as a basic step, the heating of a mixture containing a pyridic base, an organic or inorganic acid and 4,5,6,7-tetrahydro-N-(2,6-dichlorophenyl)-isatin or its O-acyl or O-alkyl derivatives.

专利号:US-6720439-B1
优先权日:2001-09-28
标题:Synthesis of ruthenium-hydride complexes and preparation procedures of chiral alcohols and ketones
发明人:OHKUMA TAKESHI; KOIZUMI MASATOSHI; MUNIZ KILIAN; NOYORI RYOJI
权利人:INST NAGOYA IND SCIENCE RES
摘要:trans-RuH(eta<1>-BH4)[(S)-xylbinap][(S,S)-dpen] (0.00125 mmol), acetophenone (5.0 mmol), and 2-propanol (2.5 mL) were placed in an autoclave, and the resulting solution was repeatedly subject 5 times to a procedure of performing pressure reduction and argon introduction while stirring the solution for deaeration. A hydrogen tank was then connected to the autoclave, and after replacing the air inside an introduction tube with hydrogen, the pressure inside the autoclave was adjusted to 5 atmospheres and then hydrogen was released until the pressure dropped to 1 atmosphere. After repeating this procedure 10 times, the hydrogen pressure was adjusted to 8 atmospheres and stirring at 25° C. was performed for 12 hours. By concentrating the solution obtained by depressurization and subjecting the crude product to simple distillation, (R)-1-phenylethanol (yield: 95%) in the form of a colorless oily substance was obtained at an ee of 99%.

专利号:EP-1354875-A1
优先权日:2003-05-19
标题:Method for synthesis of (2S,3aS,7aS)-perhydroindole-2-carboxylic acid and esters thereof; and use in the synthesis of perindopril

专利号:US-8450235-B2
优先权日:2007-10-26
标题 :Supported composite particle material, production process of same and process for producing compounds using supported composite particle material as catalyst for chemical synthesis
发明人:SUZUKI KEN; YAMAGUCHI TATSUO
权利人:SUZUKI KEN; YAMAGUCHI TATSUO; ASAHI KASEI CHEMICALS CORP
摘要:A supported composite particle material comprises: a composite particle formed of an oxidized nickel and X (wherein X represents at least one of elements selected from the group consisting of nickel, palladium, platinum, ruthenium, gold, silver and copper); and a support on which the composite particle is supported, the supported composite particle material having a supported layer in which the composite particle is localized.

专利号:CN-108927219-A
优先权日:2017-05-25
标题:Green and efficient synthesis of metalloporphyrin conjugated polymers and catalytic oxidation of cyclic ketones to prepare lactones

专利号:CN-116837043-A
优先权日:2023-07-13
标题 :Application of a reductive aminase in asymmetric synthesis of chiral amines

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合成参考文献


摘要:Santana, V. C. S.; Munaretto, L. S.; de Lucca, E. C., Jr., Science of Synthesis Knowledge Updates, (2022) 1, 214.
摘要:Levinger, S., Science of Synthesis: Stereoselective Synthesis, (2011) 3, 754.
摘要:Faber, K.; Hall, M., Science of Synthesis: Biocatalysis in Organic Synthesis, (2015) 2, 217.
摘要:de Gonzalo, G.; van Berkel, W. J. H.; Fraaije, M. W., Science of Synthesis: Biocatalysis in Organic Synthesis, (2015) 3, 214.
摘要:Wu, X.; Liu, Y.; Jin, Z., Science of Synthesis, (2022) , 68.
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