CAS: 3289-50-7; 4-Amino-2,6-Dimethoxypyrimidine

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186435-66-5 873-83-6 696-45-7

上下游产品

CAS号6320-15-6 2,4-二甲氧基-6-氯嘧啶 | CAS号122-11-2 磺胺二甲氧嗪 | CAS号73978-74-2 4-Pyrimidinamin... | CAS号90057-09-3 2,4-二甲氧基-7h-吡咯并... | CAS号555-25-9 磺胺二甲氧嘧啶D4 N4-乙酸

6-氯-2,4-甲氧基嘧啶置于bis(1,5-Cyclooctadiene)Nickel (0),(R,Sp)-Cypf-Cy,氨,Lithium Tert-Butoxide体系中,用 1,4-二氧六环,甲苯 作为反应溶剂,化学反应 16.0H,以70%的收率获得产物4-氨基-2,6-二甲氧基嘧啶
参考文献:镍催化氨的单芳基化
标题:镍催化氨的单芳基化
摘要:结构多样的(杂)芳基氯,溴化物和甲苯磺酸盐亲电子体被用于ni催化的氨单芳基化反应,包括化学选择性转化.所采用的josiphos / [ni(cod)2]催化剂体系使得能够使用市售的氨气储备溶液,或在这些反应中使用氨气,从而证明了所报道方案的多功能性和潜在的可扩展性.原理验证实验证明,空气稳定的[(josiphos)nicl 2]预催化剂可成功用于此类转化.
DOI:10.1002/anie.201410875

专利信息

专利号:US-9751851-B2
优先权日:2013-09-20
标 题:Molecules and compositions that inhibit gram negative bacteria and their uses
发明人：BASSLER BONNIE L; SEMMELHACK MARTIN F; DRESCHER KNUT; SIRYAPORN ALBERT; CONRAD-MILLER LAURA C; O'LOUGHLIN COLLEEN T
权利人:UNIV PRINCETON; BASSLER BONNIE L; SEMMELHACK MARTIN F; DRESCHER KNUT; SIRYAPORN ALBERT; MILLER LAURA C; O'LOUGHLIN COLLEEN T
摘要:Antivirulence strategies to combat Pseudomonas aeruginosa , are described. One strategy encompasses synthesis of a series of compounds that inhibit the production of pyocyanin, a redox-active virulence factor produced by this pathogen. A related strategy encompasses synthesis of compounds that inhibit the two P. aeruginosa quorum-sensing receptors, LasR and RhlR, inhibit production of pyocyanin, and inhibit biofilm formation.

专利号:JP-2000281611-A
优先权日:1999-03-30
标 题 :Synthesis of phenolic compound having protected hydroxy group, and radioactive ray-sensitive composition by using the same

专利号:CN-109293582-A
优先权日:2018-10-29
标 题:A kind of preparation method of synthesis 4- amino -2,6- dimethoxypyridin