📜色胺,(R)-(+)-对甲苯亚磺酸d-甲酯置于正丁基锂,三甲基氯硅烷体系中,用 四氢呋喃,正己烷 用作溶剂,化学反应 2.25H,以68%的收率获得(S)-N-(-)-对甲苯基亚磺酰基色胺
参考文献:Enantiopure Tetrahydro-β-Carbolines Via Pictet−spengler Reactions With N-Sulfinyl Tryptamines
标题:Enantiopure Tetrahydro-β-Carbolines Via Pictet−spengler Reactions With N-Sulfinyl Tryptamines
摘要:The Influence Of N-Sulfinyl Chiral Auxiliaries On The Stereochemistry Of The Pictet-Spengler Reaction Has Been Investigated. From Enantiopure (R)-N-Beta-Toluenesulfinyltryptamine A New And Efficient Route To Enantiopure Tetrahydro-Beta-Carbolines Has Been Established.
Doi:10.1021/ol006034T