CAS: 141745-71-3; N-((2'-Cyano-[1,1'-Biphenyl]-4-yl)Methyl)-1-Pentanamidocyclopentanecarboxamide

英文名称N-((2'-Cyano-[1,1'-Biphenyl]-4-yl)Methyl)-1-Pentanamidocyclopentanecarboxamide
中文名称N-[(2'-氰基[1,1'-联苯]-4-基)甲基]-1-[(1-氧代戊基)氨基]环戊烷甲酰胺
IUPAC名称N-((2'-cyano-[1,1'-biphenyl]-4-yl)methyl)-1-pentanamidocyclopentane-1-carboxamide
其它别名N-[(2'-Cyano[1,1'-Biphenyl]-4-yl)Methyl]-1-[(1-Oxopentyl)Amino]Cyclopentanecarboxamide; Irbesartan Impurity 3/n-((2’-Cyanobiphenyl-4-yl)Methyl)-1-Pentanamido Cyclopentane Carboxamide; N-((2''-Cyano-[1,1''-Biphenyl]-4-yl)Methyl)-1-Pentanamidocyclopentanecarboxamide; Cyclopentanecarboxamide, N-[(2'-Cyano[1,1'-Biphenyl]-4-yl)Methyl]-1-[(1-Oxopentyl)Amino]-; N-((2'-Cyano-[1,1'-Biphenyl]-4-yl)Methyl)-1-Pentanamidocyclopentanecarboxamide; 1-[(2'-Cyano[1,1'-Biphenyl]-4-yl)Methylamino]-N-Pentanoylcyclopentanecarboxamide
CAS编号141745-71-3
MFCD编号:MFCD30186930
FDA UNII编号:687VKP5PUD
分子式:C25H29N3O2分子量:403.53
产品CID: 639060
产品分类分析化学 → 标准品 → 药典标准品和杂质标准品

相似结构搜索
InChIKey: YRCWDKATYITJDZ-UHFFFAOYSA-N
InChI=1S/C25H29N3O2/c1-2-3-10-23(29)28-25(15-6-7-16-25)24(30)27-18-19-11-13-20(14-12-19)22-9-5-4-8-21(22)17-26/h4-5,8-9,11-14H,2-3,6-7,10,15-16,18H2,1H3,(H,27,30)(H,28,29
计算化学: 氢键受体数3.0氢键供体数2.0可旋转键数8.0

MSDS等安全信息

GHS符号GHS07
警示词Warning
危险描述H315-H319
防范说明P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313

上下游产品

N-pentanoylamin°Cyclopentane-1-carboxylic acid [(2'-cyanobiphenyl-4-yl)methyl]amine 1-cyano-1-n-pentanoylamin°Cyclopentane n-valeryl chloride 2-butyl-3-{4-[2-(1H-tetrazol-5-yl)phenyl]benzyl}-1,3-diazaspiro[4.4]non-1-en-4-one 2-n-butyl-4-spir°Cyclopentane-1-[((2'-tetrazol-5-yl)biphenyl-4-yl)methyl]-2-imidazolin-5-one hydr°Chloride 4'-[(2-butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]-[1,1'-biphenyl]-2-carbonitrile

合成工艺路线路线简述

📜环亮氨酸置于sodium Hydroxide,1-羟基苯并三唑,N,N'-二环己基碳二亚胺体系中,用二氯甲烷,水,甲苯用作溶剂,化学反应 2.0H,反应生成N-[(2'-氰基[1,1'-联苯]-4-基)甲基]-1-[(1-氧代戊基)氨基]环戊烷甲酰胺
参考文献:A New Entry To Antihypertensive Active Pharmaceutical Ingredient,Irbesartan And Its Analogues
标题:A New Entry To Antihypertensive Active Pharmaceutical Ingredient,Irbesartan And Its Analogues
摘要:
Doi:10.1515/hc.2006.12.5.323