专利号:US-4451565-A 优先权日:1981-03-10 标 题:Enzyme-mediated synthesis of esters and lactones 发明人:GATFIELD IAN; SAND THEODOR 权利人:HAARMANN & REIMER GMBH 摘要:In the enzyme-mediated synthesis of an ester or lactone from at least one carboxylic acid of the formula R-CH2-CH2-COOH wherein R is a hydrogen atom, or a hydrocarbon radical which has 1 to 21 carbon atoms and which can be optionally substituted by hydroxyl groups or alkoxy groups with 1 to 10 carbon atoms, with at least one primary or secondary alcohol having 1 to 15 carbon atoms, the improvement which comprises employing as the enzyme the esterase from Mucor miehei and effecting the synthesis in the absence of water. Advantageously, the synthesis is effected at about room temperature, the mol ratio of carboxylic acid to alcohol is from about 1:1 to 1:1.1, and the enzyme is used in a quantity of about 3 to 20% by weight of the carboxylic acid. The absence of water facilitates recovery, as by distillation.
专利号:WO-2009003796-A1 优先权日:2007-06-29 标 题:Method for the synthesis of neral by the isomerization of isocitrals 发明人:SCHMIDT-LEITHOFF JOACHIM; JAEKEL CHRISTOPH; PACIELLO ROCCO; HEYDRICH GUNNAR; HEIDEMANN THOMAS 权利人:BASF SE; SCHMIDT-LEITHOFF JOACHIM; JAEKEL CHRISTOPH; PACIELLO ROCCO; HEYDRICH GUNNAR; HEIDEMANN THOMAS 摘要:The present invention relates to a method for the synthesis of neral and/or geranial by the isomerization of one or more isocitrals. In particular, the invention relates to a method for the synthesis of neral in pure or enriched form, starting out from a mixture of materials containing neral and geranial and one or more isocitrals.
专利号:EP-1373548-B1 优先权日:2002-04-08 标 题 :Chemo-enzymatic synthesis of optically enriched rose-oxides 发明人:TANEJA SHUBASH CHANDRA; SETHI VIJAY KUMAR; KOUL SURRINDER; ANDOTRA SAMAR SINGH; QAZI GHULAM NABI 权利人:COUNCIL SCIENT IND RES 摘要:The present invention relates to a process for the synthesis of optically enriched dextro- and leavo-rotatory isomers of rose oxide from racemic citronellol.
专利号:US-2024309142-A1 优先权日:2023-03-17 标题 :Capped block copolymers, their synthesis, manufacture, and methods of use 发明人:MAN VICTOR FUK-PONG; LI XIAOJIN HARRY; CHEN YIQING; PU GANG; HUNT JR CLINTON 权利人:ECOLAB USA INC 摘要:This disclosure relates to capped block copolymers, preferably reverse block copolymers capped with a hydrophobic group. Preferred hydrophobic groups include benzyl groups and silyl groups. In a preferred embodiment, the reverse block copolymer has at least two arms, wherein each arm is capped with a hydrophobic group. The disclosure also provides for the synthesis of the capped block copolymers as well as methods of using the capped block copolymers for defoaming and antifoaming applications.
专利号:WO-2007013156-A1 优先权日:2005-07-27 标题 :Method for producing citral hydride 发明人:IKUSHIMA YUTAKA; MAYA CHATTERJEE 权利人:NAT INST OF ADVANCED IND SCIEN; IKUSHIMA YUTAKA; MAYA CHATTERJEE 摘要:Provided is a method for producing a citral hydride, which comprises hydrogenating citral in the presence of hydrogen and a supported-type noble metal catalyst by the use of carbon dioxide in a subcritical or supercritical state as a reaction medium. The method is a novel technique for producing a citral hydride, which allows the synthesis of a citral hydride, in particular, a citral hydride having a high content of geraniol which has a trans isomer purity higher than 98% from citral (which is a cis/trans mixture) with high conversion and high selectivity.
专利号:US-6703213-B2 优先权日:1998-02-02 标 题:Substrate analogs for MurG, methods of making same and assays using same 发明人:KAHNE SUZANNE WALKER; MEN HONGBIN; PARK PETER; GE MIN 权利人:UNIV PRINCETON 摘要:General methods for monitoring the activity of MurG, a GlcNAc transferase involved in bacterial cell wall biosynthesis, is disclosed. More particularly, the synthesis of simplified substrate analogs of Lipid I (the natural substrate for MurG), which function as acceptors for UDP-GlcNAc in an enzymatic reaction catalyzed by MurG, is described. Assays using the substrate analogs of the invention are further disclosed, which are useful for identifying a variety of other substrates, including inhibitors of MurG activity, for facilitating mechanistic and/or structural studies of the enzyme and for other uses. High throughput assays are also described.