CAS: 13205-46-4; 4-Isopropoxybenzoic Acid

相似化合物

18962-05-5 91949-95-0 35826-59-6

上下游产品

CAS号122488-52-2 ethyl 4-isoprop... | CAS号99-76-3 尼泊金甲酯 | CAS号75-26-3 2-溴丙烷 | CAS号120-47-8 尼泊金乙酯 | CAS号67-63-0 异丙醇 | CAS号35826-59-6 4-异丙氧基苯甲酸甲酯 | CAS号56-23-5 四氯化碳 | CAS号4191-73-5 尼泊金异丙酯 | CAS号7637-07-2 三氟化硼 | CAS号35826-59-6 4-异丙氧基苯甲酸甲酯 | CAS号36823-82-2 4-异丙氧基苯甲酰氯 | CAS号99-96-7 4-羟基苯甲酸 | CAS号156629-52-6 3-nitro-4-propa... | CAS号213598-07-3 3-氯-4-异丙氧基苯甲酸 | CAS号1088965-37-0 GSK-923295 | CAS号1240137-87-4 N-((s)-1-氨基-3-(... | CAS号66849-11-4 2-异丙氧基苯甲酰氯 | CAS号67032-12-6 3-(2-methylpipe...

4-异丙氧基苯甲酸甲酯置于碘,氢化铝体系中,用 乙腈 用作溶剂,化学反应 18.0H,以90%的收率获得4-异丙氧苯甲酸
参考文献:铝和碘对羧酸酯的裂解
标题:铝和碘对羧酸酯的裂解
摘要:描述了一种在非水解条件下使羧酸酯脱保护的一锅法方法.在无水乙腈中,铝粉和碘的作用下,典型的羧酸烷基酯很容易解封为羧酸.切割内酯得到相应的ω-碘代烷基羧酸.乙酸芳基酯在相邻基团的参与下进行脱乙酰化.该方法能够在芳基酯存在下选择性裂解烷基羧酸酯.
Doi:10.1021/acs.Joc.1C00034

专利信息

专利号:US-9388147-B2
优先权日:2009-11-13
标题 :Selective sphingosine 1 phosphate receptor modulators and methods of chiral synthesis
发明人：MARTINBOROUGH ESTHER; BOEHM MARCUS F; YEAGER ADAM RICHARD; TAMIYA JUNKO; HUANG LIMING; BRAHMACHARY ENUGURTHI; MOORJANI MANISHA; TIMONY GREGG ALAN; BROOKS JENNIFER L; PEACH ROBERT; SCOTT FIONA LORRAINE; HANSON MICHAEL ALLEN
权利人:RECEPTOS INC; CELGENE INTERNAT II SÃ RL
摘要:Compounds that selectively modulate the sphingosine 1 phosphate receptor are provided including compounds which modulate subtype 1 of the S1P receptor. Methods of chiral synthesis of such compounds are provided. Uses, methods of treatment or prevention and methods of preparing inventive compositions including inventive compounds are provided in connection with the treatment or prevention of diseases, malconditions, and disorders for which modulation of the sphingosine 1 phosphate receptor is medically indicated.

专利号:EP-3515880-B1
优先权日:2017-03-17
标题:Methods and compositions for synthesis of encoded libraries
发明人：LI JIN; MORGAN BARRY A; Wan jinqiao; DOU DENGFENG; LIU GUANSAI; CHANG YONG; CHEN QIUXIA; WANG XING; XU YANSHAN; HU DONGYAN; LIU JIAN; CHENG XUEMIN
权利人:HITGEN INC

专利号:US-2020149034-A1
优先权日:2017-03-17
标题:Methods and Compositions for Synthesis of Encoded Libraries

专利号:BR-122018077504-B1
优先权日:2009-11-13
标题 :METHODS FOR SYNTHESIS OF SELECTIVE SPHINGOSINE 1 PHOSPHATE RECEPTOR MODULATORS

专利号:US-9217012-B2
优先权日:2009-04-08
标题 :Inhibitors of protein tyrosine phosphatases
发明人：ZHANG ZHONG-YIN; ZHANG SHENG
权利人:ZHANG ZHONG-YIN; ZHANG SHENG; UNIV INDIANA RES & TECH CORP
摘要:Disclosed herein are compounds that selectively inhibit members of the PTP family of enzymes. Synthesized compounds demonstrated selective inhibition of TC-PTP. Also provided are methods of using the compounds and formulations containing the compounds. Also described is a fluorescence-tagged combinatorial library synthesis and screening method. And methods of using these compounds to effect enzyme activity both in cells and in vitro as well as method of using these compounds to treat diseases in human and animals.

专利号:EP-3406142-B1
优先权日:2009-11-13
标题:Selective sphingosine 1 phosphate receptor modulators and methods of chiral synthesis