CAS: 123-62-6; Propionic Anhydride

上下游产品

monoperoxyphthalic acid diethyl ether 3,4-hexanedione prop-1-en-1-one1-thiophen-2-yl-propan-1-one 2-(2-propionyloxy-benzyl)-benzofuran-3-carboxylic acid α-naphthyl propionate estradiol dipropionate

📜丙酸置于chloro(1,5-Cyclooctadiene)Rhodium(I) Dimer,N-(2-Methylbenzoyl)-8-Aminoquinoline,Sodium Carbonate,N,N'-二环己基碳二亚胺体系中,用 甲苯 用作溶剂,化学反应 0.25H,以58%的收率获得丙酸酐
参考文献:Rh催化脱羰基邻c-H烷基化(杂)芳烃与烷基羧酸的简便方法
标题:Rh催化脱羰基邻c-H烷基化(杂)芳烃与烷基羧酸的简便方法
摘要:已经开发了一种简便有效的方法,用于用市售羧酸对(杂)芳烃中的 C-H 键进行直接邻位烷基化反应.该策略是通过将羧酸原位转化为酸酐来启动的,酸酐无需分离,就经历了 Rh 催化的含有 8-氨基喹啉的芳基甲酰胺的直接脱羰基交叉偶联.该反应以高区域选择性进行,并表现出广泛的底物范围以及官能团耐受性.
Doi:10.1039/d1Ra03992J

专利信息

专利号:US-2015284338-A1
优先权日:2012-11-21
标 题:Industrial process for the synthesis of pyrimidinyl-piperazine derivatives
发明人：SZAVICSKÓ KRISZTINA; Domány György; Czibula László; Bartáné Szalai Gizella; Dobay László; WERKNÉ PAP ÉVA
权利人:RICHTER GEDEON NYRT
摘要:Our invention relates to trans-(4-{4-[2-(4-amino-cyclohexyl)-ethyl]-piperazin-1-yl}-5,6-dichloro-pyrimidin-2-yl)-methylamine dihydrochloride monohydrate, the process for the synthesis of this compound, the new (4,5-dichloro-6-piperazin-1-yl-pyirimidin-2-yl)-methylamine monohydrochlorid used as starting material in this synthesis, as well as the industrial process for the synthesis of trans-N-(4- {2-[4-(5,6-dichloro-2-methyl-amino-pyirimidin-4-yl-)piperazin-1-yl]-ethly}cyclohexyl-propionamide starting from trans-(4-{4-[2-(4-amino-cyclohexyl)-ethyl]-piperazin-1-yl}-5,6-dichloro-pyrimidin-2-yl)-methylamine dihydrochloride monohydrate.

专利号:WO-2024084491-A1
优先权日:2022-10-21
标题:Process for synthesis of res metirom and its intermediates thereof
发明人：MEHTA NILESH VIPINCHANDRA
权利人:MEHTA NILESH VIPINCHANDRA
摘要:The present invention discloses a process for synthesis of Res metirom and its intermediates thereof. More particularly, the invention discloses process for synthesis of a key intermediate, 6-(4-amino, 2,6-dichlorophenoxy)4- isopropylpyridazin-3(2H)-one, of Res metirom via novel intermediate compounds of formula A. Wherein, R is selected from methyl, ethyl and propyl.

专利号:US-7692019-B2
优先权日:2000-12-04
标 题:Methods for the stereoselective synthesis of substituted piperidines
发明人：AQUILA BRIAN M; BANNISTER THOMAS D; CUNY GREGORY D; HAUSKE JAMES R; HEFFERNAN MICHELE L R; HOEMANN MICHAEL Z; KESSLER DONALD W; SHAO LIMING; WU XINHE; XIE ROGER L
权利人:SEPRACOR INC
摘要:One aspect of the present invention relates to methods of synthesizing substituted piperidines. A second aspect of the present invention relates to stereoselective methods of synthesizing substituted piperidines. The methods of the present invention will find use in the synthesis of compounds useful for treatment of numerous ailments, conditions and diseases that afflict mammals, including but not limited to addiction and pain. An additional aspect of the present invention relates to the synthesis of combinatorial libraries of the substituted piperidines using the methods of the present invention. An additional aspect of the present invention relates to enantiomerically substituted pyrrolidines, piperidines, and azepines.

专利号:US-3906004-A
优先权日:1968-12-09
标题 :Stereoselective synthesis of intermediate for preparation of meso-nordihydroguaiaretic acid
发明人：PERRY CLARK WILLIAM
权利人:HOFFMANN LA ROCHE
摘要:This invention is directed to the stereoselective synthesis of the food additive meso-nordihydroguaiaretic acid from a protected ortho dihydroxy benzene and intermediates in this synthesis.

专利号:US-9029547-B1
优先权日:2013-12-07
标 题 :Synthesis of 4-aryl 4-acyl piperidine, its salts and analogs using indium metal
发明人：MAJEED MUHAMMED; RAMANUJAM RAJENDRAN; NAGABHUSHANAM KALYANAM
权利人:MAJEED MUHAMMED; RAMANUJAM RAJENDRAN; NAGABHUSHANAM KALYANAM
摘要:A novel process for the synthesis of 4-aryl 4-acyl piperidine derivatives using indium metal is described. Specifically, a novel process for the synthesis of 4-acetyl 4-phenyl piperidine and its salts using indium metal is described. This divisional application is specifically drawn to compounds 4-aryl 1,4-diacyl piperidine and 1,4 diacetyl 4-phenyl piperidine.

专利号:US-9056868-B1
优先权日:2012-09-13
标题 :Three-step synthesis of CL-20
发明人：WRIGHT MICHAEL E
权利人:US NAVY
摘要:Embodiments of the invention relate to the synthesis of CL-20 using only a three step synthesis and because of increased catalyst activity and lifetimes, a continuous flow process can be used with a tremendous reduction in total cost of producing CL-20.