CAS: 1193-65-3; 3-Quinuclidinone Hydrochloride

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CAS号3684-26-2 1-azabicyclo[2.... | CAS号1619-34-7 奎宁环-3-醇 | CAS号110056-51-4 3-hydroxyimino-... | CAS号95566-71-5 4-(甲氧基羰基)-1-哌啶乙酸乙酯 | CAS号108-88-3 甲苯 | CAS号107220-26-8 3-(疏基甲基)-1-阿杂环[... | CAS号3731-38-2 3-奎宁环酮 | CAS号33601-77-3 3-氯奎宁环 盐酸盐 | CAS号35423-17-7 3-奎宁环酮肟 | CAS号827-61-2 乙酰克里定 | CAS号283-38-5 1,4-二氮杂双环[3.2.2]壬烷 | CAS号53619-11-7 1,4-二氮杂双环[3.2.2... | CAS号64168-68-9 螺[1-氮杂双环[2.2.2]... | CAS号128200-13-5 1-Azabicyclo(2,... | CAS号1619-34-7 奎宁环-3-醇

奎宁环-3-醇置于n-甲基咪唑,四(乙腈)三氟甲磺酸铜(I),4,4'-二甲氧基-2,2'-联吡啶,Abno,氧气,盐酸体系中,用 乙腈,乙醚 用作溶剂,化学反应 2.0H,以82%的收率获得3-奎宁环酮盐酸盐
参考文献:Copper(I)/abno-Catalyzed Aerobic Alcohol Oxidation: Alleviating Steric And Electronic Constraints Of Cu/tempo Catalyst Systems
标题:Copper(I)/abno-Catalyzed Aerobic Alcohol Oxidation: Alleviating Steric And Electronic Constraints Of Cu/tempo Catalyst Systems
摘要:Cu/tempo Catalyst Systems Promote Efficient Aerobic Oxidation Of Sterically Unhindered Primary Alcohols And Electronically Activated Substrates,But They Show Reduced Reactivity With Aliphatic And Secondary Alcohols. Here,We Report A Catalyst System,Consisting Of ((Meo)Bpy)Cu-I(Otf) And Abno ((Meo)Bpy = 4,4'-Dimethoxy-2,2'-Bipyridine; Abno = 9-Azabicyclo[3.3.1]Nonane N-Oxyl),That Mediates Aerobic Oxidation Of All Classes Of Alcohols,Including Primary And Secondary Allylic,Benzylic,And Aliphatic Alcohols With Nearly Equal Efficiency. The Catalyst Exhibits Broad Functional Group Compatibility,And Most Reactions Are Complete Within 1 H At Room Temperature Using Ambient Air As The Source Of Oxidant.
Doi:10.1021/ja409241H

专利信息

专利号:FR-2777278-A1
优先权日:1998-04-09
标 题:NOVEL PROCESS FOR THE PREPARATION OF 3-HYDROXYMETHYL QUINUCLIDINE INTERMEDIATE SYNTHESIS OF MEQUITAZINE

专利号:CN-107089979-B
优先权日:2017-06-29
标 题 :A kind of synthesis technology of palonosetron Hcl hydrochloride

专利号:CN-107290453-B
优先权日:2017-06-29
标题:The HPLC analysis method of palonosetron Hcl synthesis intermediate product

专利号:CN-108822101-A
优先权日:2018-08-29
标题 :A kind of method of Michael addition synthesis benzhydryl quinuclidone

专利号:RU-2056418-C1
优先权日:1991-03-27
标题:Derivatives of substituted imidazolidine-2-one, method of their synthesis and pharmaceutical composition