CAS: 114-91-0; 2-(2-Methoxyethyl)Pyridine

相似化合物

103-74-2 28672-54-0 70715-19-4

📜2-((E)-2-Methoxy-Vinyl)-Pyridine置于5%-Palladium/activated Carbon,氢气体系中,用 四氢呋喃 用作溶剂,化学反应 12.0H,反应生成2-(2-甲氧基乙基)吡啶
参考文献:磷腈基t-Bu-P4催化β-(杂)芳基乙基醚的催化胺化反应.
标题:磷腈基t-Bu-P4催化β-(杂)芳基乙基醚的催化胺化反应.
摘要:我们描述了使用有机超碱t-Bu-P4的胺与β-(杂)芳基乙胺的催化胺化反应,以获得β-(杂)芳基乙胺.该反应具有广泛的底物范围,并允许缺电子和电子中性的β-(杂)芳基乙基醚与各种胺(包括吡咯,N-烷基苯胺,二苯胺,苯胺,吲哚和二氢吲哚衍生物)转化.机理研究表明,甲醇从底物上消除的两个反应途径是形成(杂)芳基烯烃,然后进行烯烃的加氢胺化.
Doi:10.1021/acs.Orglett.9B02309

专利信息

专利号:US-11548898-B2
优先权日:2017-07-06
标题 :Synthesis of halichondrins
发明人：KISHI YOSHITO; AI YANRAN; YE NING; WANG QIAOYI; YAHATA KENZO; ISO Kentaro; NAINI SANTHOSH REDDY; YAMASHITA SHUJI; LEE JIHOON; OHASHI ISAO; FUKUYAMA TAKASHI
权利人:HARVARD COLLEGE; EISAI R&D MAN CO LTD
摘要:The present invention provides methods for the synthesis of ketones involving a Ni/Zr-mediated coupling reaction. The Ni/Zr-mediated ketolization reactions can be used in the synthesis of halichondrins (e.g., halichondrin A, B, C; homohalichondrin A, B, C; norhalichondrin A, B, C), and analogs thereof. Therefore, the present invention also provides synthetic methods useful for the synthesis of halichondrins, and analogs thereof. Also provided herein are compounds (i.e., intermediates) useful in the synthesis of halichondrins, and analogs thereof. In particular, the present invention provides methods and compounds useful in the synthesis of compound of Formula (H3-A).

专利号:US-2023128195-A1
优先权日:2017-07-06
标 题:Synthesis of halichondrins

专利号:CN-118515685-A
优先权日:2017-07-06
标题 :Synthesis of halichondrin

专利号:CN-111433211-B
优先权日:2017-07-06
标题 :Synthesis of Halichondrin

专利号:EP-3649135-B1
优先权日:2017-07-06
标 题 :Synthesis of halichondrins

专利号:EP-4169924-A2
优先权日:2017-07-06
标题 :Synthesis of halichondrins