CAS: 1072944-20-7; (6-(4-Fluorophenyl)Pyridin-3-yl)Boronic Acid
该化合物是松木-宫浦交叉反应中广泛使用的多用途激酸衍生物,该化合物的特点是六点方位以四氟联苯组替代的环和三点方位的boron酸功能,使其成为制药和材料化学中有价值的建筑块.其用电排出氟化物的替代成分会增强催化联动反应的再活性,而会为金属催化剂提供更多的协调点.该化合物在标准处理条件下表现出了良好的稳定性,并表现出与各种卤化亚麻剂的高度兼容性,使得两亚利物结构能够高效合成.该产品通常作为白色供应给高纯度(> 95%)的高纯度的非白结晶粉,适合要求合成应用.
- 英文名称(6-(4-Fluorophenyl)Pyridin-3-yl)Boronic Acid
- 中文名称(6-(4-氟苯基)吡啶-3-基)硼酸
- IUPAC名称(6-(4-fluorophenyl)pyridin-3-yl)boronic acid
- 其它别名6-(4-氟苯基)吡啶-3-硼酸; 6-(4-Fluorophenyl)Pyridine-3-Boronic Acid
- CAS编号1072944-20-7
- MFCD编号:MFCD09037487
- 分子式:C11H9BFNO2分子量:217.01
- 产品CID: 111052
- 产品分类有机原料→分子砌块→芳杂环类化合物→吡啶类化合物
相似化合物
1073354-81-0 155079-10-0 1029654-19-0物理性质
MSDS等安全信息
合成工艺路线路线简述
专利信息
专利号:US-11225655-B2
优先权日:2010-04-16
标题:Bi-functional complexes and methods for making and using such complexes
发明人：GOULIAEV ALEX HAAHR; FRANCH THOMAS; GODSKESEN MICHAEL ANDERS; JENSEN KIM BIRKEBAEK
权利人:GOULIAEV ALEX HAAHR; FRANCH THOMAS; GODSKESEN MICHAEL ANDERS; JENSEN KIM BIRKEBAEK; NUEVOLUTION AS
摘要:The present invention is directed to a method for the synthesis of a bi-functional complex comprising a molecule part and an identifier oligonucleotide part identifying the molecule part. A part of the synthesis method according to the present invention is preferably conducted in one or more organic solvents when a nascent bi-functional complex comprising an optionally protected tag or oligonucleotide identifier is linked to a solid support, and another part of the synthesis method is preferably conducted under conditions suitable for enzymatic addition of an oligonucleotide tag to a nascent bi-functional complex in solution.
