CAS: 6443-69-2; 1,2,3-Trimethoxy-5-Methylbenzene

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CAS号86-81-7 3,4,5-三甲氧基苯甲醛 | CAS号3840-31-1 3,4,5-三甲氧基苯甲醇 | CAS号67-56-1 甲醇 | CAS号109-73-9 正丁胺 | CAS号4003-98-9 1-(2-hexyl)-2,5... | CAS号104-15-4 对甲苯磺酸 | CAS号13061-96-6 甲基硼酸 | CAS号51699-89-9 2,6-二溴-4-甲基苯甲醚 | CAS号108853-15-2 1,2,3-trimethox... | CAS号3066-90-8 2,3-二甲氧基-5-甲基-1... | CAS号605-94-7 2,3-二甲氧基-5-甲基-1,4-苯醌 | CAS号39068-88-7 2,3,4-三甲氧基-6-甲基苯酚 | CAS号35896-58-3 2,3,4,5-四甲氧基甲苯 | CAS号4179-19-5 3,5-二甲氧基甲苯 | CAS号22383-86-4 2-羟基-3,4-二甲氧基-6... | CAS号220899-03-6 苯菌酮 | CAS号72092-48-9 acetic acid 3,4... | CAS号86-81-7 3,4,5-三甲氧基苯甲醛

1-Methyl-3,4,4,5-Tetramethoxy-2,5-Cyclohexadien-1-Ol置于dimethyl Sulfide Borane体系中,用 二氯甲烷-D2 作为反应溶剂,化学反应 0.1H,以82%的收率获得产物3,4,5-三甲氧基甲苯
参考文献:Reductive And Nonreductive Aromatization Of Quinol Ketal Glycals. Models For The Preparation Of C-Aryl Glycoside Natural Products
标题:Reductive And Nonreductive Aromatization Of Quinol Ketal Glycals. Models For The Preparation Of C-Aryl Glycoside Natural Products
摘要:
DOI:10.1021/jo00114A057

专利信息

专利号:US-2007260076-A1
优先权日:2003-12-05
标 题:Practical, Cost-Effective Synthesis of Ubiquinones
发明人：LIPSHUTZ BRUCE H; BERL VOLKER; SHEIN KARIN; WETTERICH FRANK
权利人:LIPSHUTZ BRUCE H; BERL VOLKER; SHEIN KARIN; WETTERICH FRANK
摘要:The present invention provides a convergent method for the synthesis of ubiquinones and ubiquinone analogues. Also provided are precursors of ubiquinones and their analogues that are useful in the methods of the invention. The invention further provides an improved method for the carboalumination of alkyne substrates.

专利号:US-2008039642-A1
优先权日:2004-09-23
标题 :Practical, Cost-Effective Synthesis of Chloromethylated 1, 4-Benzoquinones
发明人：BERL VOLKER; WETTERICH FRANK; ERNST HANSGEORG; SCHEIN KARIN
权利人:BERL VOLKER; WETTERICH FRANK; ERNST HANSGEORG; SCHEIN KARIN
摘要:The present invention relates to a practical and cost-effective method for the synthesis of 5-chloromethylated 2,3-dialkoxy-6-alkyl-1,4-benzoquinones by direct chloromethylation of the corresponding 2,3-dialkoxy-6-alkyl-1,4-benzoquinones. The invention further relates to a method for the preparation of 5-chloromethylated 2,3-dialkoxy-6-alkyl-1,4-benzoquinones starting from a 3,4,5-trialkoxy-1-alkyl-benzene. The invention also relates to a method for the production of Coenzymes Q n , especially coenzyme Q 10 .

专利号:US-7528271-B2
优先权日:2007-05-16
标 题:Intermediates, process for their preparation and synthesis of 1,4-benzoquiones
发明人：BJOERSVIK HANS-RENE
权利人:BERGEN TEKNOLOGIOVERFORING AS
摘要:The present invention discloses a new process for the preparation of 1,4-benzoquiones of formula (II) n nwherein R 1 , R 2 , R 3 and R 4 are independently selected from the group consisting of branched or unbranched C 1 -C 6 alkyl, phenyl and benzyl, wherein phenyl and benzyl is optionally substituted by one or more substituent independently selected from the group consisting of C 1 -C 6 alkyl and halogen, and wherein C 1 -C 6 alkyl is optionally substituted with one or more halogen susbstituents, and wherein R 2 and R 3 together can form a C 1 -C 6 -alkylene radical, optionally substituted by one or more susbstituents independently selected from the group comprising C 1 -C 6 , benzyl, phenyl and halogen. One preferred compound is 2,3-dimethoxy-5-methyl-[1,4]benzoquinone, also known as coenzyme Q 0 (CoQ 0 ). Also disclosed are novel compounds and intermediates, and a method for the preparation of coenzyme Q n , preferable the coenzyme Q 10 . Also disclosed is a method for continuous synthesis of 1,4-benzoquiones in a continuous flow reactor.

专利号:US-5932726-A
优先权日:1996-12-16
标 题 :Asymmetric synthesis of benzoxazinones
发明人：PIERCE MICHAEL ERNEST; CHOUDHURY ANUSUYA; PARSONS JR RODNEY LAWRENCE; RADESCA LILIAN ALICIA
权利人:DU PONT PHARM CO
摘要:The present invention provides novel methods for the asymmetric synthesis of (S)-6-chloro-4-cyclopropylethynyl-4-trifluoromethyl-1,4-dihydro-2H-3,1-benzoxazin-2-one of formula (VI-i) ##STR1## which is useful as a human immunodeficiency virus (HIV) reverse transcriptase inhibitor.

专利号:US-6040480-A
优先权日:1997-04-07
标题 :Asymmetric synthesis of benzoxazinones
发明人：PIERCE MICHAEL E; CHEN CHENG Y; CHOUDHURY ANUSUYA; RADESCA LILIAN A; TAN LUSHI; ZHAO DALIAN
权利人:DU PONT PHARM CO
摘要:The present invention provides novel methods for the asymmetric synthesis of (S)-6-chloro-4-cyclopropylethynyl-4-trifluoromethyl-1,4-dihydro-2H-3,1-benzoxazin-2-one of formula (VI-i) which is useful as a human immunodeficiency virus (HIV) reverse transcriptase inhibitor.

专利号:US-6140434-A
优先权日:1999-01-08
标 题 :Synthesis of high vinyl rubber
发明人：HALASA ADEL FARHAN; HSU WEN-LIANG
权利人:GOODYEAR TIRE & RUBBER
摘要:Metal salts of saturated aliphatic alcohols can be used as modifiers in lithium initiated solution polymerizations of diene monomers into rubbery polymers. Sodium t-amylate is a preferred modifiers because of its exceptional solubility in non-polar aliphatic hydrocarbon solvents that are employed as the medium for such solution polymerizations. However, using sodium t-amylate as the polymerization modifier in commercial operations where recycle is required can lead to certain problems. These problems arise due to the fact that sodium t-amylate reacts with water to form t-amyl alcohol during steam stripping in the polymer finishing step. Since t-amyl alcohol forms an azeotrope with hexane, it co-distills with hexane and thus contaminates the feed stream. The present invention solves the problem of recycle stream contamination. This invention is based upon the discovery of highly effective modifiers that do not co-distill with hexane or-form-compounds during steam stripping which co-distill with hexane. The modifiers of this invention are metal salts of cyclic alcohols. Since the boiling points of these metal salts of cyclic alcohols are very high, they do not co-distill with hexane and contaminate recycle streams. Additionally, metal salts of cyclic alcohols are considered to be environmentally safe. The, subject invention more specifically discloses an initiator system which is comprised of (a) a lithium initiator, (b) a metal salt of a cyclic alcohol, and (c) a polar modifier.