CAS: 3676-85-5; 5-Aminoisoindoline-1,3-Dione

该化合物是一种有机化合物,其结构特征是其结构,包括一个带有氨基聚氨基芯,与芳香环的4个位置相连;该化合物一般是黄色至橙色晶状固体,以相对高的熔点闻名;可溶于二甲基硫氧化物和二甲基二甲基二亚硫酰胺(DMF)等有机溶性,但水溶性有限. 4-亚丁二酰胺因其在各个领域的应用而引人注目,包括有机合成,在其中它充当染料和荧光材料的前体;此外,它具有有趣的光物理特性,有助于传感器和成像剂的开发;氨基组的存在增强了它的再活性,允许进一步的功能化和改变;安全因素,与许多有机化合物一样,应予考虑,包括适当的处理和处置程序,以减轻任何潜在危害.

结构式图片

欧盟法规

ECHA物质C&L通报REACH预注册

上下游产品

CAS号89-40-7 4-硝基邻苯二甲酰亚胺 | CAS号610-27-5 4-硝基邻苯二甲酸 | CAS号152294-81-0 5-氨基-2-[2-(二甲基氨... | CAS号3682-14-2 异鲁米诺 | CAS号2021-26-3 5-Phenyl-1H-iso... | CAS号64169-34-2 5-溴苯酞 | CAS号6941-75-9 4-溴邻苯二甲酰亚胺 | CAS号65399-05-5 5-氨基苯酞 | CAS号7147-90-2 4-氯酞酰亚胺 | CAS号34613-09-7 5-氰基邻苯二甲酰亚胺 | CAS号178308-61-7 1,4-二氯二氮杂萘-6-甲腈 | CAS号68930-97-2 4-氨基-N-丁基苯并吡咯酮

合成工艺路线路线简述

    4-硝基邻苯二甲酸置于盐酸,碳酸氢铵,Tin(Ll) Chloride体系中,用 水 作为反应溶剂,化学反应 1.0H,反应生成 4-氨基邻苯二甲酰亚胺
    参考文献:Sinha,Girish Kumar; Mehra; Kumar,Sharad,Oriental Journal Of Chemistry,2011,Vol. 27,# 3,P. 1261-1264
    标题:Sinha,Girish Kumar; Mehra; Kumar,Sharad,Oriental Journal Of Chemistry,2011,Vol. 27,# 3,P. 1261-1264

    海关参考信息

    专利信息


    专利号:US-2024024489-A1
    优先权日:2020-11-20
    标 题:Protected disaccharides, their process of preparation and their use in the synthesis of zwitterionic oligosaccharides, and conjugates thereof
    发明人:MULARD LAURENCE; DHARA DEBASHIS; PFISTER HELENE; PAOLETTI JULIE; PHALIPON ARMELLE; GUERREIRO-INVERNO CATHERINE
    权利人:PASTEUR INSTITUT
    摘要:The present invention provides zwitterionic oligosaccharides, in particular fragments of the surface polysaccharides from Shigella sonnei and Shigella sonnei conjugates comprising them. The present invention also provides protected disaccharides, their process of preparation and their use in the synthesis of zwitterionic oligosaccharides, and conjugates thereof, the disaccharide repeating unit of Shigella sonnei being: (I)

    专利号:US-10919904-B2
    优先权日:2016-08-17
    标 题 :Northern-southern route to synthesis of bacteriochlorins
    发明人:LIU YIZHOU; LINDSEY JONATHAN S; ALLU SRINIVASA RAO; FUJITA HIKARU
    权利人:UNIV NORTH CAROLINA STATE
    摘要:Described herein are chlorins, bacteriochlorins, methods and intermediates for the synthesis of bacteriochlorins, and methods of using such bacteriochlorins for, among other things, diagnostic and therapeutic purposes such as luminescent compounds in flow cytometry, and as active agents in photodynamic therapy (PDT).

    专利号:US-12108759-B2
    优先权日:2018-11-04
    标 题:Synthesis of antimicrobial carbon dots and uses thereof
    发明人:JELINEK RAZ; BHATTACHARYA SAGARIKA; OTIS GIL
    权利人:B G NEGEV TECHNOLOGIES & APPLICATIONS LTD AT BEN GURION UNIV
    摘要:The present invention relates to antibacterial carbon dots, having aminoguanidine functionality on their outermost surface. The invention further relates to the synthesis of said antibacterial carbon dots, and to the uses of these carbon dots for inhibiting a biofilm formation in the presence of said carbon dots and as fluorescent labeling markers for specific bacteria.

    专利号:US-10882813-B2
    优先权日:2014-12-17
    标 题:Method for the synthesis of ferric oraganic compounds
    发明人:PULLAGURLA MANIK REDDY; NANDA KUMAR MECHERIL VALSAN; RANGISETTY JAGADEESH BABU; BHUDETI RAJESH; NAGARAPU RADHA
    权利人:BIOPHORE INDIA PHARMACEUTICALS PVT LTD
    摘要:The present invention relates to an improved method for the synthesis of Ferric Citrate and also to provide an amorphous form of Ferric Citrate having an active surface area less than 14 sq.m/g.

    专利号:US-8088602-B1
    优先权日:2001-12-05
    标题 :Manipulation of RNA stability and protein synthesis using thio-phosphate
    发明人:FRAYNE ELIZABETH GAY
    权利人:FRAYNE ELIZABETH GAY
    摘要:The present invention describes the use of thio-phosphate as a novel metabolite for chemically modifying mRNA in cells. Thio-phosphate is taken up by both prokaryotic and eukaryotic cells, incorporated into rNTP pools and ultimately mRNA. This enables the in vivo modification of mRNA with nuclease resistant phosphorothioate internucleotide linkages. Significant incorporation of thio-phosphate occurs such that RNA is significantly stabilized from degradation both in vivo and in vitro upon subsequent isolation. Thio-phosphate can be used as the sole source of phosphate in the culture medium for several generations resulting in a significant increase in the amount of mRNA per cell. The method should facilitate the detection and analysis of mRNA for research and diagnostic purposes. To enhance protein production it is necessary to use a mixture of thio-phosphate and phosphate in the culture medium. Generally a specific ratio of thio-phosphate to phosphate results in the optimal synthesis of many proteins for a given organism. Significant increases in both native and recombinant proteins are possible with the use of thio-phosphate in the culture media. The method represents a significant advance for cell culture with the potential to not only enhance a variety of fermentation reactions but to also potentially stimulate cellular differentiation for a variety of therapeutic purposes.

    专利号:US-6362009-B1
    优先权日:1997-11-21
    标 题 :Solid phase synthesis of heterocycles
    发明人:MUNOZ BENITO; CHEN CHIXU
    权利人:MERCK & CO INC
    摘要:Methods for solid phase and combinatorial synthesis using a resin activation/capture approach are provided. In particular, methods for the production of dihydropyridones, N-acyidihydropyridones, tetrahydropyridones, pyridines, aminopyridines, N-acyltetrahydropyridines and tetrahydropyridines compounds and libraries containing such compounds are provided. Methods for screening the libraries and compounds and pharmaceutical compositions containing compounds prepared by the methods are provided.
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    合成参考文献


    参考文献:10.1063/1.2199829
    摘要:Milischuk AA, Matyushov DV. Quadrupolar solvatochromism: 4-amino-phthalimide in toluene. J Chem Phys. 2006 May 28;124(20):204502. doi: 10.1063/1.2199829.
    参考文献:10.1016/b978-0-12-386932-6.00002-8
    摘要:Klymchenko AS, Mely Y. Fluorescent environment-sensitive dyes as reporters of biomolecular interactions. Prog Mol Biol Transl Sci. 2013;113():35–58. doi: 10.1016/b978-0-12-386932-6.00002-8.
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