1,3-二氨基胍盐酸盐,4-Chlorobenzaldoxime置于盐酸体系中,用 水,异丙醇 用作溶剂,化学反应 1.0H,以95%的收率获得罗贝胍 参考文献:Method For The Preparation Of 1,3-Bis(P-Chlorobenzylideneamino)Guanidine 标题:Method For The Preparation Of 1,3-Bis(P-Chlorobenzylideneamino)Guanidine 摘要: Doi:10.1007/bf00773100
专利号:US-11753656-B2 优先权日:2013-08-15 标 题:Methods for the improvement of product yield and production in a microorganism through glycerol recycling 发明人:ARGYROS AARON; KENEALY WILLIAM R; STONEHOUSE EMILY 权利人:LALLEMAND HUNGARY LIQUIDITY MAN LLC 摘要:The present invention provides for novel metabolic pathways to reduce or modulate glycerol production and increase product formation. More specifically, the invention provides for a recombinant microorganism comprising one or more native and/or heterologous proteins that function to import glycerol and one or more native and/or heterologous enzymes that function in one or more engineered metabolic pathways to convert a carbohydrate source, such as lignocellulose, to a product, such as ethanol, wherein the one or more native and/or heterologous proteins or enzymes is activated, upregulated, or downregulated. The invention also provides for a recombinant microorganism comprising one or more native or heterologous proteins that function to regulate glycerol synthesis and one or more native and/or heterologous enzymes that function in one or more engineered metabolic pathways to convert a carbohydrate source to ethanol, wherein said one or more native and/or heterologous proteins or enzymes is activated, upregulated or downregulated. Also provided are methods for increasing cellular glycerol uptake and increasing recombinant production of fuels and other chemicals using the recombinant microorganisms of the invention.
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合成参考文献
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