CAS: 17696-11-6; 8-Bromooctanoic Acid

相似化合物

29823-21-0 26825-92-3 77383-17-6

上下游产品

CAS号50816-19-8 8-溴-1-辛醇 | CAS号50816-20-1 1-溴-8-(四氢吡喃氧基)辛烷 | CAS号29823-21-0 8-溴辛酸乙酯 | CAS号629-41-4 1,8-辛二醇 | CAS号18719-24-9 7-辛烯酸 | CAS号6557-85-3 Propanedioic ac... | CAS号54863-44-4 8-bromo°Ctanenitrile | CAS号502-49-8 环辛酮 | CAS号629-03-8 1,6-二溴己烷 | CAS号123-99-9 壬二酸 | CAS号106689-24-1 9-硫代硬脂酸 | CAS号105339-02-4 Ethyl 2-heptynoate | CAS号50816-20-1 1-溴-8-(四氢吡喃氧基)辛烷 | CAS号50816-19-8 8-溴-1-辛醇 | CAS号544-35-4 亚油酸乙酯 | CAS号37688-96-3 1,14-二溴十四烷 | CAS号106-79-6 癸二酸二甲酯 | CAS号26825-89-8 16-溴十六烷酸甲酯 | CAS号1472-93-1 十八烷二酸二甲酯 | CAS号1459-62-7 N-(cyclo°Ctylid...

壬二酸置于水,对甲苯磺酸,Silver Nitrate,Potassium Hydroxide,Sodium Hydroxide体系中,用 乙醇,水,甲苯 用作溶剂,化学反应 12.83H,反应生成8-溴辛酸
参考文献:Synthesis,Antiproliferation,And Docking Studies Of N-Phenyl-Lipoamide And 8-Mercapto-N-Phenyloctanamide Derivatives: Effects Of C6 Position Thiol Moiety
标题:Synthesis,Antiproliferation,And Docking Studies Of N-Phenyl-Lipoamide And 8-Mercapto-N-Phenyloctanamide Derivatives: Effects Of C6 Position Thiol Moiety
摘要:Some N-Phenyl Lipoamide And 8-Mercapto-N-Phenyloctanamide Derivatives Were Synthesized And Their In Vitro Antiproliferative Activity Was Evaluated. The Experimental Results Indicated That 8-Mercapto-N-Phenyloctanamides Might Be Good Histone Deacetylase Inhibitors Rather Than N-Phenyl Lipoamides,Who Had Thiol Moiety At C6 Position. To Verify The Antiproliferation Data On Structural Basis,In Silico Docking Studies Of The Representative Compounds Into The Crystal Structure Of Histone Deacetylase-Like Protein Using Autodock 4.0 Program Were Performed. Furthermore,Sulfur Acetylated 8-Mercapto-N-Phenyloctanamide Improved Its In Vitro Antiproliferative Activity,Probably Due To The Increasing Of Its Cell Membrane Permeability. While The Identification Of Enzymatic Target Of N-Phenyl Lipoamides With Dithiolane Is Still Ongoing.
Doi:10.1007/s00044-011-9879-7

专利信息

专利号:US-9765027-B2
优先权日:2014-08-22
标题 :Substituted 1-arylethyl-4-acylaminopiperidine derivatives as opioid/alpha-adrenoreceptor modulators and method of their preparation
发明人：VARDANYAN RUBEN S; HRUBY VICTOR J
权利人:THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIV OF ARIZAONA; UNIV ARIZONA
摘要:The invention provides compounds that bind with high affinities to the μ-, δ- and κ-opioid receptors and α 2 -adrenoreceptor. In addition to providing these compounds with novel pharmacological binding properties, the invention also describes detailed novel methods for the preparation of representative compounds and a scheme for the synthesis of related compounds that bind to the opioid receptors and/or α 2 -adrenoreceptor.

专利号:US-12441760-B2
优先权日:2013-08-29
标 题 :Amino diacids containing peptide modifiers
发明人：BARLOS KLEOMENIS; GATOS DIMITRIOS; BARLOS KOSTAS K; VASILEIOU ZOI
权利人:CHEMICAL & BIOPHARMACEUTICAL LABORATORIES OF PATRAS S A
摘要:The present invention relates to peptide modifier compounds of Formula (1), or a salt thereof, wherein: a is an integer from 1 to 10, more preferably from 1 to 3; b is an integer from 0 to 7; Z is a terminal group and Y is a bivalent group. Further aspects of the invention relate to intermediates in the preparation of compounds of Formula (1), and the use of compounds of Formula (1) in the synthesis of peptide derivatives.

专利号:US-7038072-B2
优先权日:2002-07-24
标 题 :Process for monoalkylation of C-H acidic methylene groups
发明人：BODMANN KERSTIN; MEYER OLIVER; KAUFHOLD MANFRED; FIEKER JUERGEN; PAULCZYNSKI RENATE
权利人:DEGUSSA
摘要:The present invention is directed to a process for the synthesis of monoalkylated C—H acidic methylene group-containing compounds, such as malonic esters, and malonic ester nitriles.

专利号:SA-02230453-B1
优先权日:2001-09-07
标 题 :Methods for the synthesis of conjugate products of an insulin polypeptide with an oligomer, and conjugate products of a proinsulin polypeptide with an oligomer (and methods for their synthesis)

专利号:EP-1430082-A4
优先权日:2001-09-07
标 题 :SYNTHESIS OF POLYPEPTIDE-OLIGOMERIC CONJUGATES OF INSULIN, AND POLYPEPTIDE-OLIGOMERIC CONJUGATES OF PROINSULIN, AND METHODS OF THEIR SYNTHESIS

专利号:US-4539410-A
优先权日:1982-09-30
标题:N-Substituted-2-(1-imidazolyl)indoles
发明人：RENFROE HARRIS B
权利人:CIBA GEIGY CORP
摘要:Various 1-carboxylic acid substituted-2-(1-imidazolyl)indoles and functional derivatives thereof are highly specific thromboxane synthetase inhibitors. Synthesis of, pharmaceutical compositions thereof, methods of treatment utilizing such compounds and intermediates for their synthesis are included.