CAS: 17176-77-1; Dibenzyl Phosphonate

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CAS号100-51-6 苯甲醇 | CAS号3724-14-9 2-羟基苯磺酰胺 | CAS号108-95-2 苯酚 | CAS号3240-34-4 碘苯二乙酸 | CAS号108549-23-1 二苄基 N,N-二异丙基亚磷酰胺 | CAS号108-68-9 3,5-二甲基苯酚 | CAS号18108-16-2 phosphorosooxym... | CAS号91-66-7 N,N-二乙基苯胺 | CAS号15205-57-9 三苄基 亚磷酸酯 | CAS号538-37-4 二苄基磷酰基氯 | CAS号78-38-6 乙基膦酸二乙酯 | CAS号756-79-6 甲基膦酸二甲酯 | CAS号990-91-0 焦磷酸四苄酯 | CAS号342808-49-5 dibenzyl [4-(hy... | CAS号1623-08-1 磷酸二苄酯 | CAS号7494-75-9 N-bis(phenylmet... | CAS号82180-48-1 [benzyl(phenylm... | CAS号82180-50-5 3-bis(phenylmet... | CAS号82181-56-4 N-bis(phenylmet...

二氮杂甲苯置于亚磷酸,乙醚体系中,化学反应生成亚磷酸二苄酯
参考文献:220.磷酸化研究.第四部分 关于氯膦酸二苄酯的使用的进一步研究以及某些替代磷酸化方法的检验
标题:220.磷酸化研究.第四部分 关于氯膦酸二苄酯的使用的进一步研究以及某些替代磷酸化方法的检验
摘要:
Doi:10.1039/jr9480001106

专利信息

专利号:WO-2024105686-A1
优先权日:2022-11-14
标 题 :A process for the synthesis of stilbene and intermediates thereof
发明人：KANUMURU RAHUL RAJU; KOCHUMALAYIL SHAJI GEORGE; SURANENI RAVIKUMAR; VANA MURALI MOHANARAO
权利人:FERTIS INDIA PVT LTD
摘要:The present invention discloses a process for the preparation of Stilbene such as Pterostilbene and Resveratrol. More particularly, the present invention discloses synthesis of Stilbene employing a novel intermediate, 5-(4-(1-ethoxyethoxy) styryl)-benzene 1,3 diol and 1-(4-(1-ethoxyethoxy) styryl)-3,5-dimethoxy- benzene.

专利号:WO-02085848-A8
优先权日:2001-04-18
标 题 :Synthesis of pancratistatin prodrugs
发明人：PETIT GEORGE R; ORR BRIAN; DUCKI SYLVIE
权利人:UNIV ARIZONA STATE; PETIT GEORGE R; ORR BRIAN; DUCKI SYLVIE
摘要:A new and efficient synthesis of the (+)-pancratistatin phosphate prodrug 2a has been accomplished. Selective protection (tetraacetate 4) of (+)-pancratistatin (1a) was followed by phosphorylation (to 5) with dibenzyl chlorophosphite (prepared in situ from dibenzyl phosphite). Cleavage of the acetate (with sodium methoxide) and benzyl (by hydrogenolysis) protecting groups followed by concomitant reaction with two equivalents of sodium methoxide afforded good yield of disodium (+)-pancratistatin phosphate (2a). Further increases in yields of the prodrug (2a) were realized by avoiding heat in the final purification steps. Fourteen (2b-o) additional metal and ammonium derived phosphate prodrugs were also synthesized.

专利号:EP-0150883-B1
优先权日:1984-02-02
标题 :Process for preparing n-(dibenzyloxyphosphoryl)-cyanamide and processes using said compounds as intermediate for the synthesis of phosphagen substances
摘要:The invention relates to a process for preparing compounds of general formula: wherein R = Hydrogen, halogen, alkyl, nitro-group; said compounds, which are indicated hereinunder with the general term <> are useful as intermediates in the synthesis of phosphagen compounds such as phosphocreatine, phosphocreatinine and similar compounds. Such process is characterized in that dibenzyloxyphosphoryl chloride is reacted with cyanamide, N-(dibenzyloxyphosphoryl)-cyanamide being produced; this latter can react with substances provided with a primary or secondary amine function, to give the corresponding guanidinoderivatives; e.g., with a sarcosine derivative to give N-(dibenzyloxyphosphoryl)-creatine or N-(dibenzyloxyphosphoryl)-creatinine.

专利号:US-8785629-B2
优先权日:2009-06-18
标题 :Phosphonates synthons for the synthesis of phosphonates derivatives showing better bioavailability
发明人：AGROFOGLIO LUIGI A; ROY VINCENT; PRADERE UGO
权利人:AGROFOGLIO LUIGI A; ROY VINCENT; PRADERE UGO; CENTRE NAT RECH SCIENT; UNIV ORLEANS
摘要:Synthons for the synthesis of phosphonates prodrugs POM and POC, especially for direct Cross Metathesis.

专利号:US-10815194-B2
优先权日:2016-11-14
标题 :Process for the preparation of mono-protected α,ω-diamino alkanes
发明人：MENGE WIRO MICHAEL PETRUS BERNARDUS
权利人:BYONDIS BV
摘要:The present invention relates to a process for the synthesis of mono-protected α,ω-diamino alkanes, the use of said process in a process for the synthesis of a linker drug comprising an α,ω-diamino alkane moiety and the use of the process of the present invention in a process for preparing an antibody-drug conjugate comprising an α,ω-diamino alkane moiety.

专利号:US-11873315-B2
优先权日:2017-06-16
标 题 :Chiral n-heterocyclic phosphorodiamidic acids (NHPAS) and derivatives as novel Brønsted acid catalysts
发明人：KANG JUN YONG; HUANG HAI
权利人:The Board of Regents of the Nevada System of Higher Education on Behalf of the Univ of Nevada; THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIV OF NEVADA LAS VE
摘要:Provided herein are diaryl and arylalkyl phosphonates, useful as intermediates in, for example, the synthesis of leukocyte elastase inhibitors, potassium channel modulators, chemiluminescence materials, and flame retardants, and methods for making same. Also provided are N-heterocyclic phosphorodiamidic acids (NHPAs) useful in reactions such as, for example, in the preparation of diaryl and arylalkyl phosphonates. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.